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A1B0V8 (A1B0V8_PARDP) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 38. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable L-aspartate dehydrogenase HAMAP MF_01265
EC=1.4.1.21 HAMAP MF_01265
Gene names
Name:nadX HAMAP MF_01265
Ordered Locus Names:Pden_1041
OrganismParacoccus denitrificans (strain Pd 1222) [Complete proteome] [HAMAP] EMBL ABL69152.1
Taxonomic identifier318586 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhodobacterales › Rhodobacteraceae › Paracoccus

Protein attributes

Sequence length265 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Function

Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate By similarity. HAMAP MF_01265

Catalytic activity

L-aspartate + H2O + NAD(P)+ = oxaloacetate + NH3 + NAD(P)H. HAMAP MF_01265

Pathway

Cofactor biosynthesis; NAD(+) biosynthesis; iminoaspartate from L-aspartate (dehydrogenase route): step 1/1. HAMAP MF_01265

Miscellaneous

The iminoaspartate product is unstable in aqueous solution and can decompose to oxaloacetate and ammonia By similarity. HAMAP MF_01265

Sequence similarities

Belongs to the L-aspartate dehydrogenase family. HAMAP MF_01265

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2020 Potential EMBL ABL69152.1
Chain21 – 265245 Potential EMBL ABL69152.1
PRO_5000182506

Sites

Active site2181 By similarity HAMAP MF_01265
Binding site1221NAD; via amide nitrogen By similarity HAMAP MF_01265
Binding site1881NAD By similarity HAMAP MF_01265

Sequences

Sequence LengthMass (Da)Tools
A1B0V8 [UniParc].

Last modified January 23, 2007. Version 1.
Checksum: C06D9AB275BFD8C5

FASTA26527,555
        10         20         30         40         50         60 
MTSPLIVSIG FGAMARSLAA SLEKGGSGLR LGGFLLPEHL PTDAPAGMRR WNSVDDLIAA 

        70         80         90        100        110        120 
RPDLVIECAT HAAVRETVPQ LLEAGIDVVI VSIGALGDAG TVARIEAAAK TGRARAIAVS 

       130        140        150        160        170        180 
GAIGGLDVLR SAKLAGLDSV AYIGRKPPTA WKGTPAERLL DLPNLKEATV FYEGDAVEAA 

       190        200        210        220        230        240 
RDYPKNTNVT AAVALAGLGF KGTRVRLIAD PAASGNTHEL EAKGAFGSFH ILLNNKPLPE 

       250        260 
NPKTSWLAAL SVEQAVLRHF SSLEV

« Hide

References

[1]"Complete sequence of chromosome 1 of Paracoccus denitrificans PD1222."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Munk A.C., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J. expand/collapse author list , Larimer F., Land M., Hauser L., Kyrpides N., Lykidis A., Spiro S., Richardson D.J., Moir J.W.B., Ferguson S.J., van Spanning R.J.M., Richardson P.
Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000489 Genomic DNA. Translation: ABL69152.1.
RefSeqYP_914848.1. NC_008686.1.

3D structure databases

ProteinModelPortalA1B0V8.
ModBaseSearch...

Protein-protein interaction databases

STRINGA1B0V8.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4579596.
GenomeReviewsGene locus Pden_1041 in contig CP000489_GR.
KEGGpde:Pden_1041.
PATRIC22853241. VBIParDen97112_1015.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1712.
HOGENOMHBG649642.
OMAECAGHSA.

Family and domain databases

HAMAPMF_01265. NadX.
[Tree]
InterProIPR005106. Asp/hSer_DH_NAD-bd.
IPR002811. Asp_DH.
IPR011182. Asp_DH_NAD_syn.
IPR020626. Asp_DH_NAD_syn_prok.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
Gene3DG3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KOK06989.
PfamPF01958. DUF108. 1 hit.
PF03447. NAD_binding_3. 1 hit.
[Graphical view]
PIRSFPIRSF005227. Asp_dh_NAD_syn. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA1B0V8_PARDP
AccessionPrimary (citable) accession number: A1B0V8
Entry history
Integrated into UniProtKB/TrEMBL: January 23, 2007
Last sequence update: January 23, 2007
Last modified: December 14, 2011
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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