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Protein

Pseudouridine synthase

Gene

Pden_0790

Organism
Paracoccus denitrificans (strain Pd 1222)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Responsible for synthesis of pseudouridine from uracil.UniRule annotation

Catalytic activityi

RNA uridine = RNA pseudouridine.UniRule annotation

GO - Molecular functioni

  1. pseudouridine synthase activity Source: InterPro
  2. RNA binding Source: InterPro

GO - Biological processi

  1. pseudouridine synthesis Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationImported

Enzyme and pathway databases

BioCyciPDEN318586:GCVQ-802-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Pseudouridine synthaseUniRule annotation (EC:5.4.99.-UniRule annotation)
Gene namesi
Ordered Locus Names:Pden_0790Imported
OrganismiParacoccus denitrificans (strain Pd 1222)Imported
Taxonomic identifieri318586 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodobacteralesRhodobacteraceaeParacoccus
ProteomesiUP000000361 Componenti: Chromosome 1

Interactioni

Protein-protein interaction databases

STRINGi318586.Pden_0790.

Structurei

3D structure databases

ProteinModelPortaliA1B058.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the pseudouridine synthase RluA family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0564.
HOGENOMiHOG000275914.
KOiK06179.
OMAiRAKANTR.
OrthoDBiEOG6P070X.

Family and domain databases

Gene3Di3.10.290.10. 1 hit.
InterProiIPR020103. PsdUridine_synth_cat_dom.
IPR006225. PsdUridine_synth_RluC/D.
IPR006224. PsdUridine_synth_RluC/D_CS.
IPR006145. PsdUridine_synth_RsuA/RluD.
IPR002942. S4_RNA-bd.
[Graphical view]
PfamiPF00849. PseudoU_synth_2. 1 hit.
PF01479. S4. 1 hit.
[Graphical view]
SMARTiSM00363. S4. 1 hit.
[Graphical view]
SUPFAMiSSF55120. SSF55120. 1 hit.
TIGRFAMsiTIGR00005. rluA_subfam. 1 hit.
PROSITEiPS01129. PSI_RLU. 1 hit.
PS50889. S4. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A1B058-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSGVQTIRVG EDEGEQRIDR WLKKRFPQLT QGAVEKMCRT GQLRVDGGRV
60 70 80 90 100
KANTRIEPGQ EVRVPPLPEG APPPAAPKAS VKQSDAEMIQ SCVLWRDEHI
110 120 130 140 150
IALNKPPGLP SQGGSGQGDR HVDGLTTALM FGYKDRPKLV HRLDKDTSGV
160 170 180 190 200
LLLARTDRIA RALSEAFRHR LTRKIYWAAV AGVPHPRMGS IKYGLVKAPG
210 220 230 240 250
RGRGGEGEKM MAVHPSAVAA TEGAKRAHTD YAVLDALGGR VSWVAMVPVT
260 270 280 290 300
GRTHQLRAHM AEIGHPIVGD GKYGGSGQEN LGDGWGAQLG GEISRKLHLH
310 320 330 340
ARMIRFEHPI TKKLITVTAP LPEHMSRTWK TLGWSENDVP EDPFAETA
Length:348
Mass (Da):37,956
Last modified:January 23, 2007 - v1
Checksum:iC983BEBDC9AF8C34
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000489 Genomic DNA. Translation: ABL68902.1.
RefSeqiWP_011747130.1. NC_008686.1.
YP_914598.1. NC_008686.1.

Genome annotation databases

EnsemblBacteriaiABL68902; ABL68902; Pden_0790.
KEGGipde:Pden_0790.
PATRICi22852734. VBIParDen97112_0766.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000489 Genomic DNA. Translation: ABL68902.1.
RefSeqiWP_011747130.1. NC_008686.1.
YP_914598.1. NC_008686.1.

3D structure databases

ProteinModelPortaliA1B058.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi318586.Pden_0790.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABL68902; ABL68902; Pden_0790.
KEGGipde:Pden_0790.
PATRICi22852734. VBIParDen97112_0766.

Phylogenomic databases

eggNOGiCOG0564.
HOGENOMiHOG000275914.
KOiK06179.
OMAiRAKANTR.
OrthoDBiEOG6P070X.

Enzyme and pathway databases

BioCyciPDEN318586:GCVQ-802-MONOMER.

Family and domain databases

Gene3Di3.10.290.10. 1 hit.
InterProiIPR020103. PsdUridine_synth_cat_dom.
IPR006225. PsdUridine_synth_RluC/D.
IPR006224. PsdUridine_synth_RluC/D_CS.
IPR006145. PsdUridine_synth_RsuA/RluD.
IPR002942. S4_RNA-bd.
[Graphical view]
PfamiPF00849. PseudoU_synth_2. 1 hit.
PF01479. S4. 1 hit.
[Graphical view]
SMARTiSM00363. S4. 1 hit.
[Graphical view]
SUPFAMiSSF55120. SSF55120. 1 hit.
TIGRFAMsiTIGR00005. rluA_subfam. 1 hit.
PROSITEiPS01129. PSI_RLU. 1 hit.
PS50889. S4. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Pd 1222Imported.

Entry informationi

Entry nameiA1B058_PARDP
AccessioniPrimary (citable) accession number: A1B058
Entry historyi
Integrated into UniProtKB/TrEMBL: January 23, 2007
Last sequence update: January 23, 2007
Last modified: April 1, 2015
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.