SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

A1AZB7

- ASSY_PARDP

UniProt

A1AZB7 - ASSY_PARDP

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Argininosuccinate synthase

Gene
argG, Pden_0499
Organism
Paracoccus denitrificans (strain Pd 1222)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-citrulline + L-aspartate = AMP + diphosphate + N(omega)-(L-arginino)succinate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei38 – 381ATP; via amide nitrogen and carbonyl oxygen By similarity
Binding sitei91 – 911Citrulline By similarity
Binding sitei96 – 961Citrulline By similarity
Binding sitei121 – 1211ATP; via amide nitrogen By similarity
Binding sitei123 – 1231Aspartate By similarity
Binding sitei127 – 1271Aspartate By similarity
Binding sitei127 – 1271Citrulline By similarity
Binding sitei128 – 1281Aspartate By similarity
Binding sitei131 – 1311Citrulline By similarity
Binding sitei182 – 1821Citrulline By similarity
Binding sitei191 – 1911Citrulline By similarity
Binding sitei267 – 2671Citrulline By similarity
Binding sitei279 – 2791Citrulline By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi11 – 199ATP By similarity

GO - Molecular functioni

  1. argininosuccinate synthase activity Source: UniProtKB-HAMAP
  2. ATP binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. arginine biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Ligase

Keywords - Biological processi

Amino-acid biosynthesis, Arginine biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciPDEN318586:GCVQ-509-MONOMER.
UniPathwayiUPA00068; UER00113.

Names & Taxonomyi

Protein namesi
Recommended name:
Argininosuccinate synthase (EC:6.3.4.5)
Alternative name(s):
Citrulline--aspartate ligase
Gene namesi
Name:argG
Ordered Locus Names:Pden_0499
OrganismiParacoccus denitrificans (strain Pd 1222)
Taxonomic identifieri318586 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodobacteralesRhodobacteraceaeParacoccus
ProteomesiUP000000361: Chromosome 1

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 408408Argininosuccinate synthaseUniRule annotationPRO_0000321315Add
BLAST

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi318586.Pden_0499.

Structurei

3D structure databases

ProteinModelPortaliA1AZB7.
SMRiA1AZB7. Positions 7-401.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0137.
HOGENOMiHOG000230093.
KOiK01940.
OMAiVEEYIWR.
OrthoDBiEOG6K9QCV.

Family and domain databases

Gene3Di3.40.50.620. 1 hit.
3.90.1260.10. 1 hit.
HAMAPiMF_00005. Arg_succ_synth_type1.
InterProiIPR001518. Arginosuc_synth.
IPR018223. Arginosuc_synth_CS.
IPR023434. Arginosuc_synth_type_1_subfam.
IPR024074. AS_cat/multimer_dom_body.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PfamiPF00764. Arginosuc_synth. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00032. argG. 1 hit.
PROSITEiPS00564. ARGININOSUCCIN_SYN_1. 1 hit.
PS00565. ARGININOSUCCIN_SYN_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A1AZB7-1 [UniParc]FASTAAdd to Basket

« Hide

MSDAPKKVVL AYSGGLDTSI ILKWLQTEYG CEVITFTADL GQGEELEPAR    50
QKAELLGIKP ENIHIVDVRE EFVRDFVFPM FRANAVYEGL YLLGTSIARP 100
LISKHLVEIA HQHGADAVAH GATGKGNDQV RFELSAYALD PSIKVIAPWR 150
EWDLTSRTKL IEFAEQNQIP IAKDKRGEAP FSVDANLLHT SSEGKALENP 200
ADEAPDYVYQ RTVSPEDAPD QPEYIEVSFE RGDAVAINGE ALSPATILTA 250
LNEYGRKHGI GRLDFVENRF VGMKSRGIYE TPGGTILLEA HRGIEQITLD 300
SGAGHLKDSI MPRYAELIYN GFWYSPEREM LQALIDKSQE HVTGTVRLKL 350
YKGGVHTVGR WSEHSLYSEK HVTFEDDAGA YDQKDAAGFI RLNALRLKLV 400
ANRNARFK 408
Length:408
Mass (Da):45,468
Last modified:January 23, 2007 - v1
Checksum:i3334B5E8EE303F82
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000489 Genomic DNA. Translation: ABL68611.1.
RefSeqiWP_011746844.1. NC_008686.1.
YP_914307.1. NC_008686.1.

Genome annotation databases

EnsemblBacteriaiABL68611; ABL68611; Pden_0499.
GeneIDi4581041.
KEGGipde:Pden_0499.
PATRICi22852130. VBIParDen97112_0466.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000489 Genomic DNA. Translation: ABL68611.1 .
RefSeqi WP_011746844.1. NC_008686.1.
YP_914307.1. NC_008686.1.

3D structure databases

ProteinModelPortali A1AZB7.
SMRi A1AZB7. Positions 7-401.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 318586.Pden_0499.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABL68611 ; ABL68611 ; Pden_0499 .
GeneIDi 4581041.
KEGGi pde:Pden_0499.
PATRICi 22852130. VBIParDen97112_0466.

Phylogenomic databases

eggNOGi COG0137.
HOGENOMi HOG000230093.
KOi K01940.
OMAi VEEYIWR.
OrthoDBi EOG6K9QCV.

Enzyme and pathway databases

UniPathwayi UPA00068 ; UER00113 .
BioCyci PDEN318586:GCVQ-509-MONOMER.

Family and domain databases

Gene3Di 3.40.50.620. 1 hit.
3.90.1260.10. 1 hit.
HAMAPi MF_00005. Arg_succ_synth_type1.
InterProi IPR001518. Arginosuc_synth.
IPR018223. Arginosuc_synth_CS.
IPR023434. Arginosuc_synth_type_1_subfam.
IPR024074. AS_cat/multimer_dom_body.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view ]
Pfami PF00764. Arginosuc_synth. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00032. argG. 1 hit.
PROSITEi PS00564. ARGININOSUCCIN_SYN_1. 1 hit.
PS00565. ARGININOSUCCIN_SYN_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Pd 1222.

Entry informationi

Entry nameiASSY_PARDP
AccessioniPrimary (citable) accession number: A1AZB7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: January 23, 2007
Last modified: September 3, 2014
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi