Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

A1AVX5

- GCH4_RUTMC

UniProt

A1AVX5 - GCH4_RUTMC

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

GTP cyclohydrolase FolE2

Gene

folE2

Organism
Ruthia magnifica subsp. Calyptogena magnifica
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Converts GTP to 7,8-dihydroneopterin triphosphate.UniRule annotation

Catalytic activityi

GTP + H2O = formate + 2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)-dihydropteridine triphosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sitei150 – 1501May be catalytically importantUniRule annotation

GO - Molecular functioni

  1. GTP cyclohydrolase I activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. 7,8-dihydroneopterin 3'-triphosphate biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Enzyme and pathway databases

BioCyciCRUT413404:GHM7-314-MONOMER.
UniPathwayiUPA00848; UER00151.

Names & Taxonomyi

Protein namesi
Recommended name:
GTP cyclohydrolase FolE2UniRule annotation (EC:3.5.4.16UniRule annotation)
Gene namesi
Name:folE2UniRule annotation
Ordered Locus Names:Rmag_0304
OrganismiRuthia magnifica subsp. Calyptogena magnifica
Taxonomic identifieri413404 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriasulfur-oxidizing symbiontsCandidatus Ruthia
ProteomesiUP000002587: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 264264GTP cyclohydrolase FolE2PRO_0000289520Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi413404.Rmag_0304.

Structurei

3D structure databases

ProteinModelPortaliA1AVX5.
SMRiA1AVX5. Positions 17-263.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GTP cyclohydrolase IV family.UniRule annotation

Phylogenomic databases

eggNOGiCOG1469.
HOGENOMiHOG000280679.
KOiK09007.
OMAiLIWFEDL.
OrthoDBiEOG6X6RBH.

Family and domain databases

HAMAPiMF_01527_B. GTP_cyclohydrol_B.
InterProiIPR022838. GTP_cyclohydrolase_FolE2.
IPR003801. GTP_cyclohydrolase_FolE2/MptA.
[Graphical view]
PfamiPF02649. GCHY-1. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00294. TIGR00294. 1 hit.

Sequencei

Sequence statusi: Complete.

A1AVX5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSAIHLPDTQ NSADTRQIII DKVGIKDITH PITYIDCDGN KIPTIGIFTM
60 70 80 90 100
TVSLSERVKG THMSRFIEIL NEGPCEFSAH NFDKIIDKVR KRLESDIAHI
110 120 130 140 150
TLNFTFFRRK KAPSSGVESM MDYQVTLYGT LNKDEVQVMM KVVVPVTSLC
160 170 180 190 200
PCSKSISKYG AHNQRSHITI KAKAAKDKTL HIEDLIDLAE RKASCELYAI
210 220 230 240 250
LKRDDEKVVT ERAYDNPAFV EDLVRDIAVD LNADDKISYY RLESENFESI
260
HNHSAYALIE NQKC
Length:264
Mass (Da):29,971
Last modified:January 23, 2007 - v1
Checksum:iB6245A9B22438F98
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000488 Genomic DNA. Translation: ABL02082.1.
RefSeqiWP_011737707.1. NC_008610.1.
YP_903553.1. NC_008610.1.

Genome annotation databases

EnsemblBacteriaiABL02082; ABL02082; Rmag_0304.
GeneIDi4555419.
KEGGirma:Rmag_0304.
PATRICi32000239. VBICanRut45856_0347.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000488 Genomic DNA. Translation: ABL02082.1 .
RefSeqi WP_011737707.1. NC_008610.1.
YP_903553.1. NC_008610.1.

3D structure databases

ProteinModelPortali A1AVX5.
SMRi A1AVX5. Positions 17-263.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 413404.Rmag_0304.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABL02082 ; ABL02082 ; Rmag_0304 .
GeneIDi 4555419.
KEGGi rma:Rmag_0304.
PATRICi 32000239. VBICanRut45856_0347.

Phylogenomic databases

eggNOGi COG1469.
HOGENOMi HOG000280679.
KOi K09007.
OMAi LIWFEDL.
OrthoDBi EOG6X6RBH.

Enzyme and pathway databases

UniPathwayi UPA00848 ; UER00151 .
BioCyci CRUT413404:GHM7-314-MONOMER.

Family and domain databases

HAMAPi MF_01527_B. GTP_cyclohydrol_B.
InterProi IPR022838. GTP_cyclohydrolase_FolE2.
IPR003801. GTP_cyclohydrolase_FolE2/MptA.
[Graphical view ]
Pfami PF02649. GCHY-1. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00294. TIGR00294. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Entry informationi

Entry nameiGCH4_RUTMC
AccessioniPrimary (citable) accession number: A1AVX5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 29, 2007
Last sequence update: January 23, 2007
Last modified: October 29, 2014
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3