A1AVH5 (GLMM_RUTMC) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Phosphoglucosamine mutase
EC=5.4.2.10

Gene names

Name:	glmM
Ordered Locus Names:	Rmag_0138

Organism

Ruthia magnifica subsp. Calyptogena magnifica [Complete proteome] [HAMAP]

Taxonomic identifier

413404 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › sulfur-oxidizing symbionts

Protein attributes

Sequence length	441 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate By similarity. HAMAP MF_01554_B
Catalytic activity	Alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate. HAMAP MF_01554_B
Cofactor	Binds 1 magnesium ion per subunit By similarity. HAMAP MF_01554_B
Post-translational modification	Activated by phosphorylation By similarity. HAMAP MF_01554_B
Sequence similarities	Belongs to the phosphohexose mutase family.

Ontologies

Keywords
Ligand	Magnesium Metal-binding
Molecular function	Isomerase
PTM	Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	magnesium ion binding Inferred from electronic annotation. Source: InterPro phosphoglucosamine mutase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 441	441	Phosphoglucosamine mutase HAMAP MF_01554_B		PRO_0000305669
Sites
	Active site	100	1	Phosphoserine intermediate By similarity
	Metal binding	100	1	Magnesium; via phosphate group By similarity
	Metal binding	239	1	Magnesium By similarity
	Metal binding	241	1	Magnesium By similarity
	Metal binding	243	1	Magnesium By similarity
Amino acid modifications
	Modified residue	100	1	Phosphoserine By similarity

Sequences

	Sequence		Length	Mass (Da)
	A1AVH5 [UniParc]. Last modified January 23, 2007. Version 1. Checksum: B962AF1CF3CE59B3	FASTA	441	47,935
	10 20 30 40 50 60 MDNYFGTDGM RGKVGVEPIT ADFFLKLGWA VGSVLAKRAK ASVIIGKDTR VSGYLFESAL 70 80 90 100 110 120 EAGFLSAGVD VGLLGPMPTP AVAYLTQTYN ASAGVVISAS HNNFQDNGVK FFSAKGLKLS 130 140 150 160 170 180 SQYQSEIEKK LAETMISVGA DKIGKAYRYE QPLGRYIEFC KSTFDRTQSL LGLNIVIDCA 190 200 210 220 230 240 NGATYHIAQS VFSELGANIN IINNTPDGFN INEHCGATDT KYLQQVVLES KADLGIAFDG 250 260 270 280 290 300 DGDRLIMIDE NGELVDGDEL VFIIAKAWQS QGRLVNNTVV GTKMSNLGMH HALRDLDIKF 310 320 330 340 350 360 IEADVGDRFV MEKMQKSGSI LGGEGSGHII CLNKTTSGDG IISALQVLEV LVKSQSSLAK 370 380 390 400 410 420 LKQSMEKYPQ ILINVKTQAR INLKNYTKLQ RTQLAVEQTL GDESRVLIRV SGTEPLIRVM 430 440 VEAKDKIIAQ QGAEKLSNIF K

References

[1]

"The Calyptogena magnifica chemoautotrophic symbiont genome." Newton I.L.G., Woyke T., Auchtung T.A., Dilly G.F., Dutton R.J., Fisher M.C., Fontanez K.M., Lau E., Stewart F.J., Richardson P.M., Barry K.W., Saunders E., Detter J.C., Wu D., Eisen J.A., Cavanaugh C.M. Science 315:998-1000(2007) [PubMed: 17303757] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000488 Genomic DNA. Translation: ABL01932.1.
RefSeq	YP_903403.1. NC_008610.1.
3D structure databases
ProteinModelPortal	A1AVH5.
ModBase	Search...
Protein-protein interaction databases
STRING	A1AVH5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4555386.
GenomeReviews	Gene locus Rmag_0138 in contig CP000488_GR.
KEGG	rma:Rmag_0138.
PATRIC	31999861. VBICanRut45856_0162.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1109.
HOGENOM	HBG644964.
OMA	ESTDNIM.
PhylomeDB	A1AVH5.
ProtClustDB	PRK10887.
Enzyme and pathway databases
BioCyc	CRUT413404:RMAG_0138-MONOMER.
Family and domain databases
HAMAP	MF_01554_B. GlmM_B. [Tree]
InterPro	IPR005844. A-D-PHexomutase_a/b/a-I. IPR016055. A-D-PHexomutase_a/b/a-I/II/III. IPR005845. A-D-PHexomutase_a/b/a-II. IPR005846. A-D-PHexomutase_a/b/a-III. IPR005843. A-D-PHexomutase_C. IPR005841. Alpha-D-phosphohexomutase_SF. IPR006352. GlmM. [Graphical view]
Gene3D	G3DSA:3.40.120.10. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
KO	K03431.
Pfam	PF02878. PGM_PMM_I. 1 hit. PF02879. PGM_PMM_II. 1 hit. PF02880. PGM_PMM_III. 1 hit. PF00408. PGM_PMM_IV. 1 hit. [Graphical view]
PRINTS	PR00509. PGMPMM.
SUPFAM	SSF53738. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
TIGRFAMs	TIGR01455. GlmM. 1 hit.
PROSITE	PS00710. PGM_PMM. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLMM_RUTMC

Accession

Primary (citable) accession number: A1AVH5

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 2, 2007
Last sequence update:	January 23, 2007
Last modified:	December 14, 2011
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program