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Protein

Pyruvate kinase

Gene

Rmag_0066

Organism
Ruthia magnifica subsp. Calyptogena magnifica
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + pyruvate = ADP + phosphoenolpyruvate.UniRule annotation

Pathwayi: glycolysis

This protein is involved in step 5 of the subpathway that synthesizes pyruvate from D-glyceraldehyde 3-phosphate.UniRule annotation
Proteins known to be involved in the 5 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Phosphoglycerate kinase (pgk)
  3. 2,3-bisphosphoglycerate-independent phosphoglycerate mutase (gpmI)
  4. Enolase (eno)
  5. Pyruvate kinase (Rmag_0066)
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes pyruvate from D-glyceraldehyde 3-phosphate, the pathway glycolysis and in Carbohydrate degradation.

GO - Molecular functioni

Keywordsi

Molecular functionKinaseUniRule annotationImported, Transferase
Biological processGlycolysisUniRule annotation
LigandMagnesiumUniRule annotation, PyruvateImported

Enzyme and pathway databases

BioCyciCRUT413404:G1G7M-75-MONOMER.
UniPathwayiUPA00109; UER00188.

Names & Taxonomyi

Protein namesi
Recommended name:
Pyruvate kinaseUniRule annotation (EC:2.7.1.40UniRule annotation)
Gene namesi
Ordered Locus Names:Rmag_0066Imported
OrganismiRuthia magnifica subsp. Calyptogena magnificaImported
Taxonomic identifieri413404 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriasulfur-oxidizing symbiontsCandidatus Ruthia
Proteomesi
  • UP000002587 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi413404.Rmag_0066.

Structurei

3D structure databases

ProteinModelPortaliA1AVA9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini3 – 341PKInterPro annotationAdd BLAST339
Domaini360 – 473PK_CInterPro annotationAdd BLAST114

Sequence similaritiesi

Belongs to the pyruvate kinase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CA9. Bacteria.
COG0469. LUCA.
HOGENOMiHOG000021558.
KOiK00873.
OMAiICVEAEK.
OrthoDBiPOG091H02AT.

Family and domain databases

Gene3Di2.40.33.10. 1 hit.
3.40.1380.20. 1 hit.
InterProiView protein in InterPro
IPR001697. Pyr_Knase.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
IPR011037. Pyrv_Knase-like_insert_dom_sf.
IPR018209. Pyrv_Knase_AS.
IPR015793. Pyrv_Knase_brl.
IPR015795. Pyrv_Knase_C.
IPR036918. Pyrv_Knase_C_sf.
IPR015806. Pyrv_Knase_insert_dom_sf.
PANTHERiPTHR11817. PTHR11817. 1 hit.
PfamiView protein in Pfam
PF00224. PK. 1 hit.
PF02887. PK_C. 1 hit.
PRINTSiPR01050. PYRUVTKNASE.
SUPFAMiSSF50800. SSF50800. 1 hit.
SSF51621. SSF51621. 2 hits.
SSF52935. SSF52935. 1 hit.
TIGRFAMsiTIGR01064. pyruv_kin. 1 hit.
PROSITEiView protein in PROSITE
PS00110. PYRUVATE_KINASE. 1 hit.

Sequencei

Sequence statusi: Complete.

A1AVA9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPRRTKILAT LGPATDKEGV LDSILEAGVN VVRINFSHGS KQEHLNRVKA
60 70 80 90 100
VRAWAQVNQT YVGVLMDLQG PKIRITTFKD GMKIQLNNGD IFALDADLDE
110 120 130 140 150
NSGNQYSVGI VYKKLPQEVR VGNVLLLDDG KIVLEVIGIK GNKINTIVTQ
160 170 180 190 200
GGILSDKKGI NLRGGGLSAN ALTEKDKKDI LIAAKAKADY VALSFPISGD
210 220 230 240 250
DVRKTKQLLK QMGCDAGVIS KIERAESLVE SVILDIIKES AGIMVARGDL
260 270 280 290 300
GVEIGDAQLP AQQKRLIKLA RSNNRIVITA TQMLESMITS PIPTRAEVFD
310 320 330 340 350
VANAVLDGTD AVMLSAETAV GNFPENAVKT MHDVCIETEK NPIAKISHHR
360 370 380 390 400
LDETFTYIDE TIAMSAMYAA NHMGTRVIVT LTESGKTAIW MSRISSGIPI
410 420 430 440 450
VAMSDKVSTL QKATLYRGVH PCFLSTKKDW IEINKAVIKR LQVGNFVYDG
460 470 480
DSVILTKGMY KNKSGGTNLM KILTVGDSEY
Length:480
Mass (Da):52,195
Last modified:January 23, 2007 - v1
Checksum:i65F8A4CFD8BD8A7A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000488 Genomic DNA. Translation: ABL01866.1.
RefSeqiWP_011737492.1. NC_008610.1.

Genome annotation databases

EnsemblBacteriaiABL01866; ABL01866; Rmag_0066.
KEGGirma:Rmag_0066.

Similar proteinsi

Entry informationi

Entry nameiA1AVA9_RUTMC
AccessioniPrimary (citable) accession number: A1AVA9
Entry historyiIntegrated into UniProtKB/TrEMBL: January 23, 2007
Last sequence update: January 23, 2007
Last modified: March 28, 2018
This is version 83 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported