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A1AQL6 (AROC_PELPD) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 32. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Chorismate synthase
EC=4.2.3.5
Alternative name(s):
5-enolpyruvylshikimate-3-phosphate phospholyase
Gene names
Name:aroC
Ordered Locus Names:Ppro_2028
OrganismPelobacter propionicus (strain DSM 2379) [Complete proteome] [HAMAP]
Taxonomic identifier338966 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Deltaproteobacteria › Desulfuromonadales › Pelobacteraceae › Pelobacter

Protein attributes

Sequence length393 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate. HAMAP MF_00300

Cofactor

Reduced flavin By similarity. HAMAP MF_00300

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 7/7. HAMAP MF_00300

Subunit structure

Homotetramer By similarity. HAMAP MF_00300

Sequence similarities

Belongs to the chorismate synthase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionchorismate synthase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 393393Chorismate synthase HAMAP MF_00300
PRO_1000071973

Sequences

Sequence LengthMass (Da)Tools
A1AQL6 [UniParc].

Last modified January 23, 2007. Version 1.
Checksum: 3E37847A4B73C196

FASTA39342,380
        10         20         30         40         50         60 
MLRYLTAGES HGPQLTAIIE GMPAGVPLLA EDINRELARR QQGYGRGDRM KIEKDQVEIL 

        70         80         90        100        110        120 
SGVRWGETLA SPLTLVVKNR DWENWSTKMS SLPEFRDESQ AVTRPRPGHA DLGGALKYGH 

       130        140        150        160        170        180 
RDLRNILERS SARETAVRVA VGAAAKALLR LFGIRVGGVV REVGGVVATD PAASFEYIWA 

       190        200        210        220        230        240 
SAGQSPLFCC DGAAEQEMKR LIDDAKGSGD TLGGVVEVQV IGVPPGLGSH VQWDRKLDAR 

       250        260        270        280        290        300 
LAMALMSIQA IKGVEVGIGF ETARRPGSQV HDEIFRDAAR TGADSGGAYY RTSNNAGGIE 

       310        320        330        340        350        360 
GGMSNGEAII LRAAMKPIPT LYKPLRSVDM LTHEPFQAAV ERSDTCAVPA ALVVAEAVVA 

       370        380        390 
VEIANAFLEK FGGDSVQEIR RNYQGYCERI RTL

« Hide

References

[1]"Complete sequence of chromosome of Pelobacter propionicus DSM 2379."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Saunders E., Brettin T., Bruce D., Han C., Tapia R., Schmutz J., Larimer F. expand/collapse author list , Land M., Hauser L., Kyrpides N., Kim E., Lovley D., Richardson P.
Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 2379.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000482 Genomic DNA. Translation: ABK99636.1.
RefSeqYP_901694.1. NC_008609.1.

3D structure databases

ProteinModelPortalA1AQL6.
SMRA1AQL6. Positions 2-392.
ModBaseSearch...

Protein-protein interaction databases

STRINGA1AQL6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4574697.
GenomeReviewsGene locus Ppro_2028 in contig CP000482_GR.
KEGGppd:Ppro_2028.
PATRIC22897121. VBIPelPro64470_2168.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0082.
HOGENOMHBG292336.
OMAMLRWLTA.
ProtClustDBPRK05382.

Family and domain databases

HAMAPMF_00300. Chorismate_synth.
[Tree]
InterProIPR000453. Chorismate_synth.
IPR020541. Chorismate_synthase_CS.
[Graphical view]
KOK01736.
PANTHERPTHR21085. Chorismate_synth. 1 hit.
PfamPF01264. Chorismate_synt. 1 hit.
[Graphical view]
PIRSFPIRSF001456. Chorismate_synth. 1 hit.
SUPFAMSSF103263. Chorismate_synth. 1 hit.
TIGRFAMsTIGR00033. AroC. 1 hit.
PROSITEPS00787. CHORISMATE_SYNTHASE_1. 1 hit.
PS00788. CHORISMATE_SYNTHASE_2. False negative.
PS00789. CHORISMATE_SYNTHASE_3. False negative.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameAROC_PELPD
AccessionPrimary (citable) accession number: A1AQL6
Entry history
Integrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: January 23, 2007
Last modified: December 14, 2011
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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