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A1APN7 (PGK_PELPD) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 46. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphoglycerate kinase

EC=2.7.2.3
Gene names
Name:pgk
Ordered Locus Names:Ppro_1694
OrganismPelobacter propionicus (strain DSM 2379) [Complete proteome] [HAMAP]
Taxonomic identifier338966 [NCBI]
Taxonomic lineageBacteriaProteobacteriaDeltaproteobacteriaDesulfuromonadalesPelobacteraceaePelobacter

Protein attributes

Sequence length399 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate. HAMAP-Rule MF_00145

Pathway

Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5. HAMAP-Rule MF_00145

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00145

Subcellular location

Cytoplasm Potential HAMAP-Rule MF_00145.

Sequence similarities

Belongs to the phosphoglycerate kinase family.

Ontologies

Keywords
   Biological processGlycolysis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglycolytic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

phosphoglycerate kinase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 399399Phosphoglycerate kinase HAMAP-Rule MF_00145
PRO_1000009642

Regions

Nucleotide binding352 – 3554ATP By similarity
Region22 – 243Substrate binding By similarity
Region61 – 644Substrate binding By similarity

Sites

Binding site381Substrate By similarity
Binding site1201Substrate By similarity
Binding site1531Substrate By similarity
Binding site2041ATP By similarity
Binding site3261ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
A1APN7 [UniParc].

Last modified January 23, 2007. Version 1.
Checksum: 5C2F66169D439D43

FASTA39943,269
        10         20         30         40         50         60 
MPIRYIDQLA DLKDKKVFIR VDFNVPQDSK GNITEDTRIT GALPTIRYAI EQGARVILAS 

        70         80         90        100        110        120 
HLGRPKGEKN EKYSMVPAAK RLSELLGRKV KQASDCFGEE VTREIDAMKS GEVLMLENVR 

       130        140        150        160        170        180 
FYPGEEKNDP KFAQQLANGC QVYVNDAFAV SHRAHASVEA ITRVIPTVVA GFLMRNEMTF 

       190        200        210        220        230        240 
FDKAMQNPVR PLVAILGGAK VSGKLEVLEK LMNKVDKVVI GGGMAFTFLK SMGYSVGASK 

       250        260        270        280        290        300 
VEDELLPTAK KIMDKARKKG IMFYLPVDCV VANAFEASAT NFITTVQEIP EGWLALDIGP 

       310        320        330        340        350        360 
ASATLFTETL RDAKTVIWNG PMGVFEMDAF ARGTFAVAEA VASAFATTII GGGDTDSAVR 

       370        380        390 
KAGVESKVSY ISTGGGAFLE LLEGKVLPGV KALDIKVKK 

« Hide

References

[1]"Complete sequence of chromosome of Pelobacter propionicus DSM 2379."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Saunders E., Brettin T., Bruce D., Han C., Tapia R., Schmutz J., Larimer F. expand/collapse author list , Land M., Hauser L., Kyrpides N., Kim E., Lovley D., Richardson P.
Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 2379.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000482 Genomic DNA. Translation: ABK99307.1.
RefSeqYP_901365.1. NC_008609.1.

3D structure databases

ProteinModelPortalA1APN7.
SMRA1APN7. Positions 1-396.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING338966.Ppro_1694.

Proteomic databases

PRIDEA1APN7.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABK99307; ABK99307; Ppro_1694.
GeneID4572429.
KEGGppd:Ppro_1694.
PATRIC22896483. VBIPelPro64470_1852.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0126.
HOGENOMHOG000227107.
KOK00927.
OMAAGHPVGK.
OrthoDBEOG64N9Z0.

Enzyme and pathway databases

BioCycPPRO338966:GHL0-1725-MONOMER.
UniPathwayUPA00109; UER00185.

Family and domain databases

Gene3D3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPMF_00145. Phosphoglyc_kinase.
InterProIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERPTHR11406. PTHR11406. 1 hit.
PfamPF00162. PGK. 1 hit.
[Graphical view]
PIRSFPIRSF000724. Pgk. 1 hit.
PRINTSPR00477. PHGLYCKINASE.
SUPFAMSSF53748. SSF53748. 1 hit.
PROSITEPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePGK_PELPD
AccessionPrimary (citable) accession number: A1APN7
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: January 23, 2007
Last modified: June 11, 2014
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways