A1APN7 (PGK_PELPD) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Phosphoglycerate kinase
EC=2.7.2.3

Gene names

Name:	pgk
Ordered Locus Names:	Ppro_1694

Organism

Pelobacter propionicus (strain DSM 2379) [Complete proteome] [HAMAP]

Taxonomic identifier

338966 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Deltaproteobacteria › Desulfuromonadales › Pelobacteraceae › Pelobacter

Protein attributes

Sequence length	399 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate. HAMAP MF_00145
Pathway	Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5. HAMAP MF_00145
Subunit structure	Monomer By similarity. HAMAP MF_00145
Subcellular location	Cytoplasm Potential HAMAP MF_00145.
Sequence similarities	Belongs to the phosphoglycerate kinase family.

Ontologies

Keywords
Biological process	Glycolysis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycolysis Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW phosphoglycerate kinase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 399	399	Phosphoglycerate kinase HAMAP MF_00145		PRO_1000009642
Regions
	Nucleotide binding	352 – 355	4	ATP By similarity
	Region	22 – 24	3	Substrate binding By similarity
	Region	61 – 64	4	Substrate binding By similarity
Sites
	Binding site	38	1	Substrate By similarity
	Binding site	120	1	Substrate By similarity
	Binding site	153	1	Substrate By similarity
	Binding site	204	1	ATP By similarity
	Binding site	326	1	ATP By similarity

Sequences

	Sequence		Length	Mass (Da)
	A1APN7 [UniParc]. Last modified January 23, 2007. Version 1. Checksum: 5C2F66169D439D43	FASTA	399	43,269
	10 20 30 40 50 60 MPIRYIDQLA DLKDKKVFIR VDFNVPQDSK GNITEDTRIT GALPTIRYAI EQGARVILAS 70 80 90 100 110 120 HLGRPKGEKN EKYSMVPAAK RLSELLGRKV KQASDCFGEE VTREIDAMKS GEVLMLENVR 130 140 150 160 170 180 FYPGEEKNDP KFAQQLANGC QVYVNDAFAV SHRAHASVEA ITRVIPTVVA GFLMRNEMTF 190 200 210 220 230 240 FDKAMQNPVR PLVAILGGAK VSGKLEVLEK LMNKVDKVVI GGGMAFTFLK SMGYSVGASK 250 260 270 280 290 300 VEDELLPTAK KIMDKARKKG IMFYLPVDCV VANAFEASAT NFITTVQEIP EGWLALDIGP 310 320 330 340 350 360 ASATLFTETL RDAKTVIWNG PMGVFEMDAF ARGTFAVAEA VASAFATTII GGGDTDSAVR 370 380 390 KAGVESKVSY ISTGGGAFLE LLEGKVLPGV KALDIKVKK

References

[1]

"Complete sequence of chromosome of Pelobacter propionicus DSM 2379." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Saunders E., Brettin T., Bruce D., Han C., Tapia R., Schmutz J., Larimer F. , Land M., Hauser L., Kyrpides N., Kim E., Lovley D., Richardson P. Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 2379.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000482 Genomic DNA. Translation: ABK99307.1.
RefSeq	YP_901365.1. NC_008609.1.
3D structure databases
ProteinModelPortal	A1APN7.
SMR	A1APN7. Positions 1-396.
ModBase	Search...
Protein-protein interaction databases
STRING	A1APN7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4572429.
GenomeReviews	Gene locus Ppro_1694 in contig CP000482_GR.
KEGG	ppd:Ppro_1694.
PATRIC	22896483. VBIPelPro64470_1852.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0126.
HOGENOM	HBG453500.
OMA	AKPMAAI.
PhylomeDB	A1APN7.
ProtClustDB	PRK00073.
Family and domain databases
HAMAP	MF_00145. Phosphoglyc_kinase. [Tree]
InterPro	IPR001576. Phosphoglycerate_kinase. IPR015901. Phosphoglycerate_kinase_C. IPR015911. Phosphoglycerate_kinase_CS. IPR015824. Phosphoglycerate_kinase_N. [Graphical view]
Gene3D	G3DSA:3.40.50.1270. Phosphoglycerate_kinase_C. 1 hit. G3DSA:3.40.50.1260. Phosphoglycerate_kinase_N. 1 hit.
KO	K00927.
PANTHER	PTHR11406. PGK. 1 hit.
Pfam	PF00162. PGK. 1 hit. [Graphical view]
PIRSF	PIRSF000724. Pgk. 1 hit.
PRINTS	PR00477. PHGLYCKINASE.
SUPFAM	SSF53748. PGK. 1 hit.
PROSITE	PS00111. PGLYCERATE_KINASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PGK_PELPD

Accession

Primary (citable) accession number: A1APN7

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	January 23, 2007
Last modified:	December 14, 2011
This is version 30 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program