A1AJX5 (A1AJX5_PELPD) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
DNA gyrase subunit B RuleBase RU003363 HAMAP MF_01898
EC=5.99.1.3 RuleBase RU003363 HAMAP MF_01898

Gene names

Name:	gyrB HAMAP MF_01898
Ordered Locus Names:	Ppro_0004

Organism

Pelobacter propionicus (strain DSM 2379) [Complete proteome] [HAMAP]

Taxonomic identifier

338966 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Deltaproteobacteria › Desulfuromonadales › Pelobacteraceae › Pelobacter

Protein attributes

Sequence length	802 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	DNA gyrase negatively supercoils closed circular double-stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings By similarity. RuleBase RU003363 HAMAP MF_01898
Catalytic activity	ATP-dependent breakage, passage and rejoining of double-stranded DNA. RuleBase RU003363 SAAS SAAS002288 HAMAP MF_01898
Subunit structure	Made up of two chains. The A chain is responsible for DNA breakage and rejoining; the B chain catalyzes ATP hydrolysis. The enzyme forms an A2B2 tetramer By similarity. HAMAP MF_01898
Subcellular location	Cytoplasm By similarity HAMAP MF_01898.
Sequence similarities	Belongs to the type II topoisomerase family. HAMAP MF_01898 RuleBase RU000380

Ontologies

Keywords
Cellular component	Cytoplasm HAMAP MF_01898
Ligand	ATP-binding SAAS SAAS002288 HAMAP MF_01898 RuleBase RU000380 Nucleotide-binding
Molecular function	Isomerase Topoisomerase SAAS SAAS002288 HAMAP MF_01898 RuleBase RU000380
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA topological change Inferred from electronic annotation. Source: InterPro DNA-dependent DNA replication Inferred from electronic annotation. Source: HAMAP
Cellular component	chromosome Inferred from electronic annotation. Source: InterPro cytoplasm Inferred from electronic annotation. Source: HAMAP
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP DNA topoisomerase (ATP-hydrolyzing) activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A1AJX5 [UniParc]. Last modified January 23, 2007. Version 1. Checksum: C0DEE9FB3EF7020D	FASTA	802	89,855
	10 20 30 40 50 60 MSEHNNVTQS NVEEYSADNI KVLEGLAAVR KRPAMYIGST SGAGLHHLVY EIVDNSIDEA 70 80 90 100 110 120 LAGHCDNISV TINVDGSVTV IDNGRGIPTD MHPTEGRSAA EVVLTVLHAG GKFDNDSYKV 130 140 150 160 170 180 SGGLHGVGVS VVNALSKWLE LEIKRDGKIF RQSYRRGDPV APLAETGATR KRGTKVTFMP 190 200 210 220 230 240 DEEIFETTEF SFDVLSQRLR ELAFLNAGVR IGISDMRVDN KSHEFYYEGG INSFVEYLNR 250 260 270 280 290 300 NKIAVHPKPI YFRGEKGGVE TEVSMQYNDS FDEKIFSFAN NINTHEGGTH LVGFKAALTR 310 320 330 340 350 360 TMNAYAAANN LLKKEKVSIS GDDLREGLTC VISVKIPQPQ FEGQTKTKLG NSEVKGYVES 370 380 390 400 410 420 MINEKLAQFL EENPQVAKRI LEKSIEAARA REAARRARET VRRKGALDLG GLPGKLADCQ 430 440 450 460 470 480 EKNPEHCELY LVEGDSAGGS AKQGRDRKFQ AILPLKGKIL NVEKSRFDKM ISSQEIRTLI 490 500 510 520 530 540 TALGTGIGKD DFDISKLRYG RIIVMTDADV DGSHILTLLL TFFYRNMNEL IQRGHLYIAQ 550 560 570 580 590 600 PPLYKVKRGK KEMYLRNEAA LQNFLLEEGA EDLVLRLEKG DRKYLGKQII PVIRQFIDNR 610 620 630 640 650 660 AIFDKVVKKG ISQELLSIIV RSNVPAGLEE LSQVEPYLEA MKELAENGEY QVEEERIIFY 670 680 690 700 710 720 IGNIRAIIDH QILGVLASHE YELLVENHRR VVETMADGRA YIEQEAGGKV LLETSNHEEL 730 740 750 760 770 780 LVYFLENAKK GLGIQRYKGL GEMNPDQLWE TTMNPENRVL LQVKIEDAVE SDEIFTILMG 790 800 DQVDPRREFI ETNALNVVNL DI

References

[1]

"Complete sequence of chromosome of Pelobacter propionicus DSM 2379." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Saunders E., Brettin T., Bruce D., Han C., Tapia R., Schmutz J., Larimer F. , Land M., Hauser L., Kyrpides N., Kim E., Lovley D., Richardson P. Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 2379.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000482 Genomic DNA. Translation: ABK97645.1.
RefSeq	YP_899703.1. NC_008609.1.
3D structure databases
ProteinModelPortal	A1AJX5.
SMR	A1AJX5. Positions 20-386.
ModBase	Search...
Protein-protein interaction databases
STRING	A1AJX5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4573876.
GenomeReviews	Gene locus Ppro_0004 in contig CP000482_GR.
KEGG	ppd:Ppro_0004.
PATRIC	22893075. VBIPelPro64470_0179.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0187.
HOGENOM	HBG304889.
OMA	DCSSRDP.
PhylomeDB	A1AJX5.
ProtClustDB	PRK14939.
Family and domain databases
HAMAP	MF_01898. GyrB. [Tree]
InterPro	IPR003594. ATPase-like_ATP-bd. IPR011557. GyrB. IPR020568. Ribosomal_S5_D2-typ_fold. IPR014721. Ribosomal_S5_D2-typ_fold_subgr. IPR001241. Topo_IIA. IPR013759. Topo_IIA_B/N_ab. IPR002288. Topo_IIA_B_C. IPR013506. Topo_IIA_bsu_dom2. IPR013760. Topo_IIA_cen. IPR018522. TopoIIA_CS. [Graphical view]
Gene3D	G3DSA:3.30.565.10. ATP_bd_ATPase. 1 hit. G3DSA:3.30.230.10. Ribosomal_S5_D2-type_fold. 1 hit. G3DSA:3.40.50.670. Topo_IIA_B/N_ab. 2 hits.
KO	K02470.
Pfam	PF00204. DNA_gyraseB. 1 hit. PF00986. DNA_gyraseB_C. 1 hit. PF02518. HATPase_c. 1 hit. [Graphical view]
PRINTS	PR00418. TPI2FAMILY.
SMART	SM00387. HATPase_c. 1 hit. SM00433. TOP2c. 1 hit. [Graphical view]
SUPFAM	SSF55874. ATP_bd_ATPase. 1 hit. SSF54211. Ribosomal_S5_D2-typ_fold. 1 hit. SSF56719. Topo_IIA_cen. 1 hit.
TIGRFAMs	TIGR01059. GyrB. 1 hit.
PROSITE	PS00177. TOPOISOMERASE_II. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A1AJX5_PELPD

Accession

Primary (citable) accession number: A1AJX5

Entry history

Integrated into UniProtKB/TrEMBL:	January 23, 2007
Last sequence update:	January 23, 2007
Last modified:	January 25, 2012
This is version 41 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)