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A1AI82 (RHAS_ECOK1) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 60. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
HTH-type transcriptional activator RhaS
Alternative name(s):
L-rhamnose operon regulatory protein RhaS
Gene names
Name:rhaS
Ordered Locus Names:Ecok1_38780
ORF Names:APECO1_2563
OrganismEscherichia coli O1:K1 / APEC [Complete proteome] [HAMAP]
Taxonomic identifier405955 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia

Protein attributes

Sequence length278 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Activates expression of the rhaBAD and rhaT operons By similarity. HAMAP-Rule MF_01534

Subunit structure

Binds DNA as a dimer By similarity. HAMAP-Rule MF_01534

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_01534.

Sequence similarities

Contains 2 HTH araC/xylS-type DNA-binding domains.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 278278HTH-type transcriptional activator RhaS HAMAP-Rule MF_01534
PRO_1000068702

Regions

DNA binding190 – 20920H-T-H motif By similarity
DNA binding239 – 26224H-T-H motif By similarity

Sites

Site2411Interaction with sigma-70 By similarity
Site2501Interaction with sigma-70 By similarity

Sequences

Sequence LengthMass (Da)Tools
A1AI82 [UniParc].

Last modified January 23, 2007. Version 1.
Checksum: 71E981876A6F21A9

FASTA27832,402
        10         20         30         40         50         60 
MTVLHSVDFF PSGNASVAIE PRLPQADFPE HHHDFHEIVI VEHGTGIHVF NGQPYTITGG 

        70         80         90        100        110        120 
TVCFVRDHDR HLYEHTDNLC LTNVLYRSPD RFQFLAGLNQ LLPQEQDGQY PSHWRVNHSV 

       130        140        150        160        170        180 
LQQVRQLVAQ MEQQEEENDL PSTASREILF MQLLLLLRKS SLQENLENSA SRLNLLLAWL 

       190        200        210        220        230        240 
EDHFADEVNW DAVADQFSLS LRTLHRQLKQ KTGLTPQRYL NRLRLMKARH LLRHSEASVT 

       250        260        270 
DIAYRCGFSD SNHFSTLFRR EFNWSPRDIR QGRDGFLQ 

« Hide

References

[1]"The genome sequence of avian pathogenic Escherichia coli strain O1:K1:H7 shares strong similarities with human extraintestinal pathogenic E. coli genomes."
Johnson T.J., Kariyawasam S., Wannemuehler Y., Mangiamele P., Johnson S.J., Doetkott C., Skyberg J.A., Lynne A.M., Johnson J.R., Nolan L.K.
J. Bacteriol. 189:3228-3236(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000468 Genomic DNA. Translation: ABJ03372.1.
RefSeqYP_859496.1. NC_008563.1.

3D structure databases

ProteinModelPortalA1AI82.
SMRA1AI82. Positions 22-83, 170-274.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING405955.APECO1_2563.

Protein family/group databases

AraC-XylSSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABJ03372; ABJ03372; APECO1_2563.
GeneID4495587.
KEGGecv:APECO1_2563.
PATRIC18220325. VBIEscCol127180_4372.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2207.
HOGENOMHOG000290513.
KOK02855.
OMAYEETAID.
OrthoDBEOG66XBBN.

Family and domain databases

Gene3D1.10.10.60. 2 hits.
2.60.120.10. 1 hit.
HAMAPMF_01534. HTH_type_RhaS.
InterProIPR003313. AraC-bd.
IPR009057. Homeodomain-like.
IPR018060. HTH_AraC.
IPR018062. HTH_AraC-typ_CS.
IPR014710. RmlC-like_jellyroll.
IPR020449. Tscrpt_reg_HTH_AraC-type.
IPR023609. Tscrpt_reg_HTH_RhaS.
[Graphical view]
PfamPF02311. AraC_binding. 1 hit.
PF12833. HTH_18. 1 hit.
[Graphical view]
PRINTSPR00032. HTHARAC.
SMARTSM00342. HTH_ARAC. 1 hit.
[Graphical view]
SUPFAMSSF46689. SSF46689. 2 hits.
SSF51215. SSF51215. 1 hit.
PROSITEPS00041. HTH_ARAC_FAMILY_1. 1 hit.
PS01124. HTH_ARAC_FAMILY_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameRHAS_ECOK1
AccessionPrimary (citable) accession number: A1AI82
Entry history
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: January 23, 2007
Last modified: May 14, 2014
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families