Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

A1AI82

- RHAS_ECOK1

UniProt

A1AI82 - RHAS_ECOK1

Protein

HTH-type transcriptional activator RhaS

Gene

rhaS

Organism
Escherichia coli O1:K1 / APEC
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 61 (01 Oct 2014)
      Sequence version 1 (23 Jan 2007)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Activates expression of the rhaBAD and rhaT operons.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sitei241 – 2411Interaction with sigma-70UniRule annotation
    Sitei250 – 2501Interaction with sigma-70UniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    DNA bindingi190 – 20920H-T-H motifUniRule annotationAdd
    BLAST
    DNA bindingi239 – 26224H-T-H motifUniRule annotationAdd
    BLAST

    GO - Molecular functioni

    1. sequence-specific DNA binding Source: InterPro
    2. sequence-specific DNA binding transcription factor activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. positive regulation of transcription, DNA-templated Source: UniProtKB-HAMAP
    2. rhamnose metabolic process Source: UniProtKB-HAMAP
    3. transcription, DNA-templated Source: UniProtKB-KW

    Keywords - Molecular functioni

    Activator

    Keywords - Biological processi

    Rhamnose metabolism, Transcription, Transcription regulation

    Keywords - Ligandi

    DNA-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    HTH-type transcriptional activator RhaSUniRule annotation
    Alternative name(s):
    L-rhamnose operon regulatory protein RhaSUniRule annotation
    Gene namesi
    Name:rhaSUniRule annotation
    Ordered Locus Names:Ecok1_38780
    ORF Names:APECO1_2563
    OrganismiEscherichia coli O1:K1 / APEC
    Taxonomic identifieri405955 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
    ProteomesiUP000008216: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 278278HTH-type transcriptional activator RhaSPRO_1000068702Add
    BLAST

    Interactioni

    Subunit structurei

    Binds DNA as a dimer.UniRule annotation

    Protein-protein interaction databases

    STRINGi405955.APECO1_2563.

    Structurei

    3D structure databases

    ProteinModelPortaliA1AI82.
    SMRiA1AI82. Positions 22-83, 170-274.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Contains 2 HTH araC/xylS-type DNA-binding domains.UniRule annotation

    Keywords - Domaini

    Repeat

    Phylogenomic databases

    eggNOGiCOG2207.
    HOGENOMiHOG000290513.
    KOiK02855.
    OMAiYEETAID.
    OrthoDBiEOG66XBBN.

    Family and domain databases

    Gene3Di1.10.10.60. 2 hits.
    2.60.120.10. 1 hit.
    HAMAPiMF_01534. HTH_type_RhaS.
    InterProiIPR003313. AraC-bd.
    IPR009057. Homeodomain-like.
    IPR018060. HTH_AraC.
    IPR018062. HTH_AraC-typ_CS.
    IPR014710. RmlC-like_jellyroll.
    IPR020449. Tscrpt_reg_HTH_AraC-type.
    IPR023609. Tscrpt_reg_HTH_RhaS.
    [Graphical view]
    PfamiPF02311. AraC_binding. 1 hit.
    PF12833. HTH_18. 1 hit.
    [Graphical view]
    PRINTSiPR00032. HTHARAC.
    SMARTiSM00342. HTH_ARAC. 1 hit.
    [Graphical view]
    SUPFAMiSSF46689. SSF46689. 2 hits.
    SSF51215. SSF51215. 1 hit.
    PROSITEiPS00041. HTH_ARAC_FAMILY_1. 1 hit.
    PS01124. HTH_ARAC_FAMILY_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A1AI82-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTVLHSVDFF PSGNASVAIE PRLPQADFPE HHHDFHEIVI VEHGTGIHVF    50
    NGQPYTITGG TVCFVRDHDR HLYEHTDNLC LTNVLYRSPD RFQFLAGLNQ 100
    LLPQEQDGQY PSHWRVNHSV LQQVRQLVAQ MEQQEEENDL PSTASREILF 150
    MQLLLLLRKS SLQENLENSA SRLNLLLAWL EDHFADEVNW DAVADQFSLS 200
    LRTLHRQLKQ KTGLTPQRYL NRLRLMKARH LLRHSEASVT DIAYRCGFSD 250
    SNHFSTLFRR EFNWSPRDIR QGRDGFLQ 278
    Length:278
    Mass (Da):32,402
    Last modified:January 23, 2007 - v1
    Checksum:i71E981876A6F21A9
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000468 Genomic DNA. Translation: ABJ03372.1.
    RefSeqiYP_859496.1. NC_008563.1.

    Genome annotation databases

    EnsemblBacteriaiABJ03372; ABJ03372; APECO1_2563.
    GeneIDi4495587.
    KEGGiecv:APECO1_2563.
    PATRICi18220325. VBIEscCol127180_4372.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000468 Genomic DNA. Translation: ABJ03372.1 .
    RefSeqi YP_859496.1. NC_008563.1.

    3D structure databases

    ProteinModelPortali A1AI82.
    SMRi A1AI82. Positions 22-83, 170-274.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 405955.APECO1_2563.

    Protein family/group databases

    AraC-XylS Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABJ03372 ; ABJ03372 ; APECO1_2563 .
    GeneIDi 4495587.
    KEGGi ecv:APECO1_2563.
    PATRICi 18220325. VBIEscCol127180_4372.

    Phylogenomic databases

    eggNOGi COG2207.
    HOGENOMi HOG000290513.
    KOi K02855.
    OMAi YEETAID.
    OrthoDBi EOG66XBBN.

    Family and domain databases

    Gene3Di 1.10.10.60. 2 hits.
    2.60.120.10. 1 hit.
    HAMAPi MF_01534. HTH_type_RhaS.
    InterProi IPR003313. AraC-bd.
    IPR009057. Homeodomain-like.
    IPR018060. HTH_AraC.
    IPR018062. HTH_AraC-typ_CS.
    IPR014710. RmlC-like_jellyroll.
    IPR020449. Tscrpt_reg_HTH_AraC-type.
    IPR023609. Tscrpt_reg_HTH_RhaS.
    [Graphical view ]
    Pfami PF02311. AraC_binding. 1 hit.
    PF12833. HTH_18. 1 hit.
    [Graphical view ]
    PRINTSi PR00032. HTHARAC.
    SMARTi SM00342. HTH_ARAC. 1 hit.
    [Graphical view ]
    SUPFAMi SSF46689. SSF46689. 2 hits.
    SSF51215. SSF51215. 1 hit.
    PROSITEi PS00041. HTH_ARAC_FAMILY_1. 1 hit.
    PS01124. HTH_ARAC_FAMILY_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The genome sequence of avian pathogenic Escherichia coli strain O1:K1:H7 shares strong similarities with human extraintestinal pathogenic E. coli genomes."
      Johnson T.J., Kariyawasam S., Wannemuehler Y., Mangiamele P., Johnson S.J., Doetkott C., Skyberg J.A., Lynne A.M., Johnson J.R., Nolan L.K.
      J. Bacteriol. 189:3228-3236(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

    Entry informationi

    Entry nameiRHAS_ECOK1
    AccessioniPrimary (citable) accession number: A1AI82
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 5, 2008
    Last sequence update: January 23, 2007
    Last modified: October 1, 2014
    This is version 61 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3