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Protein

tRNA pseudouridine synthase B

Gene

truB

Organism
Escherichia coli O1:K1 / APEC
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.UniRule annotation

Catalytic activityi

tRNA uridine(55) = tRNA pseudouridine(55).UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei43SubstrateUniRule annotation1
Active sitei48NucleophileUniRule annotation1
Binding sitei76SubstrateUniRule annotation1
Binding sitei179SubstrateUniRule annotation1
Binding sitei200SubstrateUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processtRNA processing

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA pseudouridine synthase BUniRule annotation (EC:5.4.99.25UniRule annotation)
Alternative name(s):
tRNA pseudouridine(55) synthaseUniRule annotation
Short name:
Psi55 synthaseUniRule annotation
tRNA pseudouridylate synthaseUniRule annotation
tRNA-uridine isomeraseUniRule annotation
Gene namesi
Name:truBUniRule annotation
Ordered Locus Names:Ecok1_31670
ORF Names:APECO1_3264
OrganismiEscherichia coli O1:K1 / APEC
Taxonomic identifieri405955 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000008216 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000845851 – 314tRNA pseudouridine synthase BAdd BLAST314

Structurei

3D structure databases

ProteinModelPortaliA1AG71
SMRiA1AG71
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000231223
KOiK03177
OMAiVDCSKGT

Family and domain databases

Gene3Di2.30.130.10, 1 hit
HAMAPiMF_01080 TruB_bact, 1 hit
InterProiView protein in InterPro
IPR020103 PsdUridine_synth_cat_dom_sf
IPR002501 PsdUridine_synth_N
IPR015947 PUA-like_sf
IPR036974 PUA_sf
IPR014780 tRNA_psdUridine_synth_TruB
IPR015240 tRNA_sdUridine_synth_fam1_C
IPR032819 TruB_C
PANTHERiPTHR13767 PTHR13767, 1 hit
PfamiView protein in Pfam
PF09157 TruB-C_2, 1 hit
PF16198 TruB_C_2, 1 hit
PF01509 TruB_N, 1 hit
SUPFAMiSSF55120 SSF55120, 1 hit
SSF88697 SSF88697, 1 hit
TIGRFAMsiTIGR00431 TruB, 1 hit

Sequencei

Sequence statusi: Complete.

A1AG71-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSRPRRRGRD INGVLLLDKP QGMSSNDALQ KVKRIYNANR AGHTGALDPL
60 70 80 90 100
ATGMLPICLG EATKFSQYLL DSDKRYRVIA RLGQRTDTSD ADGQIVEERP
110 120 130 140 150
VTFSAEQLAA ALDTFRGDIE QIPSMYSALK YQGKKLYEYA RQGIEVPREA
160 170 180 190 200
RPITVYELLF IRHEGNELEL EIHCSKGTYI RTIIDDLGEK LGCGAHVIYL
210 220 230 240 250
RRLAVSKYPV ERMVTLEHLR ELVEQAEQQD IPAAELLDPL LMPMDSPASD
260 270 280 290 300
YPVVNLPLTS SVYFKNGNPV RTSGAPLEGL VRVTEGENGK FIGMGEIDDE
310
GRVAPRRLVV EYPA
Length:314
Mass (Da):35,087
Last modified:January 23, 2007 - v1
Checksum:iFEA46C01E0E8E7A5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000468 Genomic DNA Translation: ABJ02661.1
RefSeqiWP_000089698.1, NC_008563.1

Genome annotation databases

EnsemblBacteriaiABJ02661; ABJ02661; APECO1_3264
KEGGiecv:APECO1_3264

Similar proteinsi

Entry informationi

Entry nameiTRUB_ECOK1
AccessioniPrimary (citable) accession number: A1AG71
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: January 23, 2007
Last modified: March 28, 2018
This is version 74 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

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