A1AG34 (A1AG34_ECOK1) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
2-hydroxy-3-oxopropionate reductase EMBL ABJ02624.1

Gene names

Name:	yhaE EMBL ABJ02624.1
Ordered Locus Names:	Ecok1_31300
ORF Names:	APECO1_3302 EMBL ABJ02624.1

Organism

Escherichia coli O1:K1 / APEC [Complete proteome] [HAMAP]

Taxonomic identifier

405955 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributes

Sequence length	299 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glyoxylate metabolic process Inferred from electronic annotation. Source: InterPro pentose-phosphate shunt Inferred from electronic annotation. Source: InterPro valine metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	2-hydroxy-3-oxopropionate reductase activity Inferred from electronic annotation. Source: InterPro 3-hydroxyisobutyrate dehydrogenase activity Inferred from electronic annotation. Source: InterPro coenzyme binding Inferred from electronic annotation. Source: InterPro nucleotide binding Inferred from electronic annotation. Source: InterPro phosphogluconate dehydrogenase (decarboxylating) activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A1AG34 [UniParc]. Last modified January 23, 2007. Version 1. Checksum: 08E65F7849754566	FASTA	299	31,049
	10 20 30 40 50 60 MIDMTMKVGF IGLGIMGKPM SKNLLKAGYS LVVADRNPEA IADVIAAGAE TASTAKAIAE 70 80 90 100 110 120 QCDVIITMLP NSPHVKEVAL GENGIIEGAK PGTVLIDMSS IAPLASREIS EALKAKGIDM 130 140 150 160 170 180 LDAPVSGGEP KAIDGTLSVM VGGDKAIFDK YYDLMKAMAG SVVHTGEIGA GNVTKLANQV 190 200 210 220 230 240 IVALNIAAMS EALTLATKAG VNPDLVYQAI RGGLAGSTVL DAKAPMVMDR NFKPGFRIDL 250 260 270 280 290 HIKDLANALD TSHGVGAQLP LTAAVMEMMQ ALRADGLGMA DHSALACYYE KLAKVEVTR

References

[1]

"The genome sequence of avian pathogenic Escherichia coli strain O1:K1:H7 shares strong similarities with human extraintestinal pathogenic E. coli genomes." Johnson T.J., Kariyawasam S., Wannemuehler Y., Mangiamele P., Johnson S.J., Doetkott C., Skyberg J.A., Lynne A.M., Johnson J.R., Nolan L.K. J. Bacteriol. 189:3228-3236(2007) [PubMed: 17293413] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000468 Genomic DNA. Translation: ABJ02624.1.
RefSeq	YP_858748.1. NC_008563.1.
3D structure databases
ProteinModelPortal	A1AG34.
SMR	A1AG34. Positions 6-299.
ModBase	Search...
Protein-protein interaction databases
STRING	A1AG34.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBESCT00000038551; EBESCP00000037068; EBESCG00000037601.
GeneID	4491471.
GenomeReviews	Gene locus Ecok1_31300 in contig CP000468_GR.
KEGG	ecv:APECO1_3302.
PATRIC	18218619. VBIEscCol127180_3547.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2084.
GeneTree	EBGT00050000009837.
HOGENOM	HBG729179.
OMA	WSRRRES.
ProtClustDB	PRK11559.
Family and domain databases
InterPro	IPR002204. 3-OH-isobutyrate_DH-rel_CS. IPR015815. 3hydroxyacid_DH/Rdtase. IPR008927. 6-PGluconate_DH_C-like. IPR006115. 6PGDH_NADP-bd. IPR013328. DH_multihelical. IPR016040. NAD(P)-bd_dom. IPR006398. Tartro_sem_red. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit. G3DSA:1.10.1040.10. Opine_DH. 1 hit.
KO	K00042.
PANTHER	PTHR22981. 3hydroxy_acid_DH. 1 hit.
Pfam	PF03446. NAD_binding_2. 1 hit. [Graphical view]
SUPFAM	SSF48179. 6DGDH_C_like. 1 hit.
TIGRFAMs	TIGR01505. Tartro_sem_red. 1 hit.
PROSITE	PS00895. 3_HYDROXYISOBUT_DH. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A1AG34_ECOK1

Accession

Primary (citable) accession number: A1AG34

Entry history

Integrated into UniProtKB/TrEMBL:	January 23, 2007
Last sequence update:	January 23, 2007
Last modified:	December 14, 2011
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)