Reviewed, UniProtKB/Swiss-Prot A1ACA3 (MPGP_ECOK1)

Names and origin

Protein names

Recommended name:
    Putative mannosyl-3-phosphoglycerate phosphatase
      Short name=MPGP
    EC=3.1.3.70

Gene names

Ordered Locus Names:	Ecok1_17990
ORF Names:	APECO1_993

Organism

Escherichia coli O1:K1 / APEC [Complete proteome] [HAMAP]

Taxonomic identifier

405955 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributes

Sequence length	271 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	2(alpha-D-mannosyl)-3-phosphoglycerate + H2O = 2(alpha-D-mannosyl)-D-glycerate + phosphate. HAMAP MF_00617
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the HAD-like hydrolase superfamily. MPGP family.

Ontologies

Keywords
Cellular component	Cytoplasm
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	mannosyl-3-phosphoglycerate phosphatase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 271	271	Putative mannosyl-3-phosphoglycerate phosphatase HAMAP MF_00617		PRO_1000061373

Sequences

	Sequence		Length	Mass (Da)
	A1ACA3-1 [UniParc]. Last modified January 23, 2007. Version 1. Checksum: 3A4CFA7E78FE20EC	FASTA	271	30,396
	10 20 30 40 50 60 MLSIQQPLLV FSDLDGTLLD SHSYDWQPAA PWLSRLREAN VPVILCSSKT SAEMLYLQKT 70 80 90 100 110 120 LGLQGLPLIA ENGAVIQLAE QWQDIDGFPR IISGISHGEI SQVLNTLREK EHFKFTTFDD 130 140 150 160 170 180 VDDATIAEWT GLSRSQAALT QLHEASVTLI WRDSDERMAQ FTARLNELGL QFMQGARFWH 190 200 210 220 230 240 VLDASAGKDQ AANWIIATYQ QSSGKRPTTL GLGDGPNDAP LLEVMDYAVI VKGLNREGVH 250 260 270 LHDEDPTRVW RTQREGPEGW REGLDHFFSA R

References

[1]

"The genome sequence of avian pathogenic Escherichia coli strain O1:K1:H7 shares strong similarities with human extraintestinal pathogenic E. coli genomes." Johnson T.J., Kariyawasam S., Wannemuehler Y., Mangiamele P., Johnson S.J., Doetkott C., Skyberg J.A., Lynne A.M., Johnson J.R., Nolan L.K. J. Bacteriol. 189:3228-3236(2007) [PubMed: 17293413] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000468 Genomic DNA. Translation: ABJ01293.1.
RefSeq	YP_853007.1.
3D structure databases
SMR	A1ACA3. Positions 1-234.
ModBase	Search...
Genome annotation databases
GeneID	4492064.
GenomeReviews	Gene locus Ecok1_17990 in contig CP000468_GR.
KEGG	ecv:APECO1_993.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	A1ACA3. LGDSPND.
Family and domain databases
HAMAP	MF_00617. [Tree]
InterPro	IPR013200. HAD-SF_hydro-like_3. IPR006379. HAD-SF_hydro_IIB. IPR006381. HAD-SF_hydro_IIB_YedP. IPR012815. MPG_phos_rel. [Graphical view]
Pfam	PF08282. Hydrolase_3. 1 hit. [Graphical view]
TIGRFAMs	TIGR01484. HAD-SF-IIB. 1 hit. TIGR01486. HAD-SF-IIB-MPGP. 1 hit. TIGR02463. MPGP_rel. 1 hit.
ProtoNet	Search...

Entry information

Entry name

MPGP_ECOK1

Accession

Primary (citable) accession number: A1ACA3

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 5, 2008
Last sequence update:	January 23, 2007
Last modified:	June 16, 2009
This is version 17 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)