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A1ABD8 (A1ABD8_ECOK1) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 40. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesSubmitted name:
Putative dethiobiotin synthetase EMBL ABJ00978.1
Gene names
Name:ynfK EMBL ABJ00978.1
Ordered Locus Names:Ecok1_14840
ORF Names:APECO1_676 EMBL ABJ00978.1
OrganismEscherichia coli O1:K1 / APEC [Complete proteome] [HAMAP]
Taxonomic identifier405955 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributes

Sequence length235 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring By similarity. SAAS SAAS004472

Catalytic activity

ATP + 7,8-diaminononanoate + CO2 = ADP + phosphate + dethiobiotin. SAAS SAAS004472

Cofactor

Magnesium By similarity. SAAS SAAS004472

Pathway

Cofactor biosynthesis; biotin biosynthesis; biotin from 7,8-diaminononanoate: step 1/2. SAAS SAAS004472

Subcellular location

Cytoplasm By similarity SAAS SAAS004472.

Sequences

Sequence LengthMass (Da)Tools
A1ABD8 [UniParc].

Last modified January 23, 2007. Version 1.
Checksum: 95C46CA35ABEA347

FASTA23525,440
        10         20         30         40         50         60 
MELVMLKRFF ITGTDTSVGK TVVSRALLQA LASQGKTVAG YKPVAKGSKE TPEGLRNKDA 

        70         80         90        100        110        120 
LVLQSVSTIE LPYEAVNPIA LSEEESSVAH SCPINYTLIS NGLANLTDKV DHVVVEGTGG 

       130        140        150        160        170        180 
WRSLMNDLRP LSEWVVQEQL PVLMVVGIQE GCINHALLTA QAIANDGLPL IGWVANRINP 

       190        200        210        220        230 
GLAHYAEIID VLGKKLPAPL IGELPYLPRA EQRELGQYIR LAMLRSVLAV DRVTV

« Hide

References

[1]"The genome sequence of avian pathogenic Escherichia coli strain O1:K1:H7 shares strong similarities with human extraintestinal pathogenic E. coli genomes."
Johnson T.J., Kariyawasam S., Wannemuehler Y., Mangiamele P., Johnson S.J., Doetkott C., Skyberg J.A., Lynne A.M., Johnson J.R., Nolan L.K.
J. Bacteriol. 189:3228-3236(2007) [PubMed: 17293413] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000468 Genomic DNA. Translation: ABJ00978.1.
RefSeqYP_852692.1. NC_008563.1.

3D structure databases

ProteinModelPortalA1ABD8.
SMRA1ABD8. Positions 7-224.
ModBaseSearch...

Protein-protein interaction databases

STRINGA1ABD8.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBESCT00000036144; EBESCP00000034661; EBESCG00000035194.
GeneID4494386.
GenomeReviewsGene locus Ecok1_14840 in contig CP000468_GR.
KEGGecv:APECO1_676.
PATRIC18214794. VBIEscCol127180_1676.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0132.
GeneTreeEBGT00050000010427.
HOGENOMHBG650065.
OMAINPGLSH.
ProtClustDBPRK12374.

Family and domain databases

HAMAPMF_00336. BioD.
[Tree]
InterProIPR002586. CbiA_P_synth.
IPR004472. DTB_synth_BioD.
[Graphical view]
KOK01935.
PfamPF01656. CbiA. 1 hit.
[Graphical view]
PIRSFPIRSF006755. DTB_synth. 1 hit.
TIGRFAMsTIGR00347. BioD. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA1ABD8_ECOK1
AccessionPrimary (citable) accession number: A1ABD8
Entry history
Integrated into UniProtKB/TrEMBL: January 23, 2007
Last sequence update: January 23, 2007
Last modified: December 14, 2011
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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