A1AB32 (OPGD_ECOK1) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Glucans biosynthesis protein D

Gene names

Name:	mdoD
Synonyms:	opgD
Ordered Locus Names:	Ecok1_13780
ORF Names:	APECO1_572

Organism

Escherichia coli O1:K1 / APEC [Complete proteome] [HAMAP]

Taxonomic identifier

405955 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia › Escherichia coli

Protein attributes

Sequence length	551 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Probably involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans (OPGs) By similarity. HAMAP-Rule MF_01068
Pathway	Glycan metabolism; osmoregulated periplasmic glucan (OPG) biosynthesis. HAMAP-Rule MF_01068
Subcellular location	Periplasm By similarity.
Post-translational modification	Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven. HAMAP-Rule MF_01068
Sequence similarities	Belongs to the OpgD/OpgG family.

Ontologies

Keywords
Cellular component	Periplasm
Domain	Signal
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	glucan biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular_component	periplasmic space Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	carbohydrate binding Inferred from electronic annotation. Source: InterPro catalytic activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 32	32	Tat-type signal Potential
	Chain	33 – 551	519	Glucans biosynthesis protein D HAMAP-Rule MF_01068		PRO_1000064545

Sequences

	Sequence		Length	Mass (Da)
	A1AB32 [UniParc]. Last modified January 23, 2007. Version 1. Checksum: E4A6DC9004C4E893	FASTA	551	62,795
	10 20 30 40 50 60 MDRRRFIKGS MAMAAVCGTS GIASLFSQAA FAADSDIADG QTQRFDFSIL QSMAHDLAQT 70 80 90 100 110 120 AWRGAPRPLP DTLATMTPQA YNSIQYDAEK SLWHNVENRQ LDAQFFHMGM GFRRRVRMFS 130 140 150 160 170 180 VDPATHLARE IHFRPELFKY NDAGVDTKQL EGQSDLGFAG FRVFKAPELA RRDVVSFLGA 190 200 210 220 230 240 SYFRAVDDTY QYGLSARGLA IDTYTDSKEE FPDFTAFWFD TVKPGATTFT VYALLDSASI 250 260 270 280 290 300 TGAYKFTIHC EKNQVIMDVE NHLYARKDIK QLGIAPMTSM FSCGTNERRM CDTIHPQIHD 310 320 330 340 350 360 SDRLSMWRGN GEWICRPLNN PQKLQFNAYT DNNPKGFGLL QLDRDFSHYQ DIMGWYNKRP 370 380 390 400 410 420 SLWVEPRNKW GKGTIGLMEI PTTGETLDNI VCFWQPEKAV KAGDEFAFQY RLYWSAQPPV 430 440 450 460 470 480 HCPLARVMAT RTGMGGFPEG WAPGEHYPEK WARRFAVDFV GGDLKAAAPK GIEPVITLSS 490 500 510 520 530 540 GEAKQIEILY IEPIDGYRIQ FDWYPTSDST DPVDMRMYLR CQGDAISETW LYQYFPPAPD 550 KRQYVDDRVM S

References

[1]

"The genome sequence of avian pathogenic Escherichia coli strain O1:K1:H7 shares strong similarities with human extraintestinal pathogenic E. coli genomes." Johnson T.J., Kariyawasam S., Wannemuehler Y., Mangiamele P., Johnson S.J., Doetkott C., Skyberg J.A., Lynne A.M., Johnson J.R., Nolan L.K. J. Bacteriol. 189:3228-3236(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000468 Genomic DNA. Translation: ABJ00872.1.
RefSeq	YP_852586.1. NC_008563.1.
3D structure databases
ProteinModelPortal	A1AB32.
SMR	A1AB32. Positions 44-538.
ModBase	Search...
Protein-protein interaction databases
STRING	405955.APECO1_572.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABJ00872; ABJ00872; APECO1_572.
GeneID	4491664.
KEGG	ecv:APECO1_572.
PATRIC	18214541. VBIEscCol127180_1550.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG3131.
HOGENOM	HOG000288262.
OMA	MYQVGEN.
ProtClustDB	PRK13273.
Enzyme and pathway databases
UniPathway	UPA00637.
Family and domain databases
Gene3D	2.60.40.10. 1 hit. 2.70.98.10. 1 hit.
HAMAP	MF_01068. MdoD_OpgD.
InterPro	IPR011013. Gal_mutarotase_SF_dom. IPR023724. Glucan_biosyn_MdoD. IPR007444. Glucan_biosyn_MdoG_C. IPR014438. Glucan_biosyn_MdoGD. IPR014718. Glyco_hydro-type_carb-bd_sub. IPR013783. Ig-like_fold. IPR014756. Ig_E-set. IPR006311. TAT_signal. IPR019546. TAT_signal_bac_arc. [Graphical view]
Pfam	PF04349. MdoG. 1 hit. [Graphical view]
PIRSF	PIRSF006281. MdoG. 1 hit.
SUPFAM	SSF74650. Gal_mut_like. 1 hit. SSF81296. Ig_E-set. 1 hit.
TIGRFAMs	TIGR01409. TAT_signal_seq. 1 hit.
PROSITE	PS51318. TAT. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

OPGD_ECOK1

Accession

Primary (citable) accession number: A1AB32

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 5, 2008
Last sequence update:	January 23, 2007
Last modified:	May 1, 2013
This is version 42 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program