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A1AB32 (OPGD_ECOK1) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 46. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucans biosynthesis protein D
Gene names
Name:mdoD
Synonyms:opgD
Ordered Locus Names:Ecok1_13780
ORF Names:APECO1_572
OrganismEscherichia coli O1:K1 / APEC [Complete proteome] [HAMAP]
Taxonomic identifier405955 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia

Protein attributes

Sequence length551 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Function

Probably involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans (OPGs) By similarity. HAMAP-Rule MF_01068

Pathway

Glycan metabolism; osmoregulated periplasmic glucan (OPG) biosynthesis. HAMAP-Rule MF_01068

Subcellular location

Periplasm By similarity HAMAP-Rule MF_01068.

Post-translational modification

Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven. HAMAP-Rule MF_01068

Sequence similarities

Belongs to the OpgD/OpgG family.

Ontologies

Keywords
   Cellular componentPeriplasm
   DomainSignal
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglucan biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentperiplasmic space

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functioncarbohydrate binding

Inferred from electronic annotation. Source: InterPro

catalytic activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 3232Tat-type signal Potential
Chain33 – 551519Glucans biosynthesis protein D HAMAP-Rule MF_01068
PRO_1000064545

Sequences

Sequence LengthMass (Da)Tools
A1AB32 [UniParc].

Last modified January 23, 2007. Version 1.
Checksum: E4A6DC9004C4E893

FASTA55162,795
        10         20         30         40         50         60 
MDRRRFIKGS MAMAAVCGTS GIASLFSQAA FAADSDIADG QTQRFDFSIL QSMAHDLAQT 

        70         80         90        100        110        120 
AWRGAPRPLP DTLATMTPQA YNSIQYDAEK SLWHNVENRQ LDAQFFHMGM GFRRRVRMFS 

       130        140        150        160        170        180 
VDPATHLARE IHFRPELFKY NDAGVDTKQL EGQSDLGFAG FRVFKAPELA RRDVVSFLGA 

       190        200        210        220        230        240 
SYFRAVDDTY QYGLSARGLA IDTYTDSKEE FPDFTAFWFD TVKPGATTFT VYALLDSASI 

       250        260        270        280        290        300 
TGAYKFTIHC EKNQVIMDVE NHLYARKDIK QLGIAPMTSM FSCGTNERRM CDTIHPQIHD 

       310        320        330        340        350        360 
SDRLSMWRGN GEWICRPLNN PQKLQFNAYT DNNPKGFGLL QLDRDFSHYQ DIMGWYNKRP 

       370        380        390        400        410        420 
SLWVEPRNKW GKGTIGLMEI PTTGETLDNI VCFWQPEKAV KAGDEFAFQY RLYWSAQPPV 

       430        440        450        460        470        480 
HCPLARVMAT RTGMGGFPEG WAPGEHYPEK WARRFAVDFV GGDLKAAAPK GIEPVITLSS 

       490        500        510        520        530        540 
GEAKQIEILY IEPIDGYRIQ FDWYPTSDST DPVDMRMYLR CQGDAISETW LYQYFPPAPD 

       550 
KRQYVDDRVM S 

« Hide

References

[1]"The genome sequence of avian pathogenic Escherichia coli strain O1:K1:H7 shares strong similarities with human extraintestinal pathogenic E. coli genomes."
Johnson T.J., Kariyawasam S., Wannemuehler Y., Mangiamele P., Johnson S.J., Doetkott C., Skyberg J.A., Lynne A.M., Johnson J.R., Nolan L.K.
J. Bacteriol. 189:3228-3236(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000468 Genomic DNA. Translation: ABJ00872.1.
RefSeqYP_852586.1. NC_008563.1.

3D structure databases

ProteinModelPortalA1AB32.
SMRA1AB32. Positions 44-538.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING405955.APECO1_572.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABJ00872; ABJ00872; APECO1_572.
GeneID4491664.
KEGGecv:APECO1_572.
PATRIC18214541. VBIEscCol127180_1550.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG3131.
HOGENOMHOG000288262.
OMACTSMYQV.
OrthoDBEOG6FZ487.

Enzyme and pathway databases

UniPathwayUPA00637.

Family and domain databases

Gene3D2.60.40.10. 1 hit.
2.70.98.10. 1 hit.
HAMAPMF_01068. MdoD_OpgD.
InterProIPR011013. Gal_mutarotase_SF_dom.
IPR023724. Glucan_biosyn_MdoD.
IPR007444. Glucan_biosyn_MdoG_C.
IPR014438. Glucan_biosyn_MdoGD.
IPR014718. Glyco_hydro-type_carb-bd_sub.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR006311. TAT_signal.
IPR019546. TAT_signal_bac_arc.
[Graphical view]
PfamPF04349. MdoG. 1 hit.
[Graphical view]
PIRSFPIRSF006281. MdoG. 1 hit.
SUPFAMSSF74650. SSF74650. 1 hit.
SSF81296. SSF81296. 1 hit.
TIGRFAMsTIGR01409. TAT_signal_seq. 1 hit.
PROSITEPS51318. TAT. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameOPGD_ECOK1
AccessionPrimary (citable) accession number: A1AB32
Entry history
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: January 23, 2007
Last modified: May 14, 2014
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways