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A1AAQ6 (A1AAQ6_ECOK1) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 57. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Enoyl-[acyl-carrier-protein] reductase [NADH] PIRNR PIRNR000094

EC=1.3.1.9 PIRNR PIRNR000094
Gene names
Name:fabI EMBL ABJ00746.1
ORF Names:APECO1_447 EMBL ABJ00746.1
OrganismEscherichia coli O1:K1 / APEC [Complete proteome] [HAMAP] EMBL ABJ00746.1
Taxonomic identifier405955 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia

Protein attributes

Sequence length262 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

An acyl-[acyl-carrier protein] + NAD+ = a trans-2,3-dehydroacyl-[acyl-carrier protein] + NADH. PIRNR PIRNR000094

Pathway

Lipid metabolism; fatty acid biosynthesis. PIRNR PIRNR000094

Sequence similarities

Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily. PIRNR PIRNR000094

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site1461Proton acceptor By similarity PIRSR PIRSR000094-1
Active site1561Proton acceptor By similarity PIRSR PIRSR000094-1
Binding site951Substrate; via amide nitrogen and carbonyl oxygen By similarity PIRSR PIRSR000094-2
Site2011Involved in acyl-ACP binding By similarity PIRSR PIRSR000094-4
Site2041Involved in acyl-ACP binding By similarity PIRSR PIRSR000094-4
Site2051Involved in acyl-ACP binding By similarity PIRSR PIRSR000094-4

Sequences

Sequence LengthMass (Da)Tools
A1AAQ6 [UniParc].

Last modified January 23, 2007. Version 1.
Checksum: 436A89AF349D1866

FASTA26227,864
        10         20         30         40         50         60 
MGFLSGKRIL VTGVASKLSI AYGIAQAMHR EGAELAFTYQ NDKLKGRVEE FAAQLGSDIV 

        70         80         90        100        110        120 
LQCDVAEDAS IDTMFAELGK VWPKFDGFVH SIGFAPGDQL DGDYVNAVTR EGFKIAHDIS 

       130        140        150        160        170        180 
SYSFVAMAKA CRSMLNPGSA LLTLSYLGAE RAIPNYNVMG LAKASLEANV RYMANAMGPE 

       190        200        210        220        230        240 
GVRVNAISAG PIRTLAASGI KDFRKMLAHC EAVTPIRRTV TIEDVGNSAA FLCSDLSAGI 

       250        260 
SGEVVHVDGG FSIAAMNELE LK 

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References

[1]"The genome sequence of avian pathogenic Escherichia coli strain O1:K1:H7 shares strong similarities with human extraintestinal pathogenic E. coli genomes."
Johnson T.J., Kariyawasam S., Wannemuehler Y., Mangiamele P., Johnson S.J., Doetkott C., Skyberg J.A., Lynne A.M., Johnson J.R., Nolan L.K.
J. Bacteriol. 189:3228-3236(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: APEC O1 EMBL ABJ00746.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000468 Genomic DNA. Translation: ABJ00746.1.
RefSeqYP_852460.1. NC_008563.1.

3D structure databases

ProteinModelPortalA1AAQ6.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING405955.APECO1_447.

Chemistry

BindingDBA1AAQ6.

Proteomic databases

PRIDEA1AAQ6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABJ00746; ABJ00746; APECO1_447.
GeneID4492237.
KEGGecv:APECO1_447.
PATRIC18214239. VBIEscCol127180_1402.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0623.
KOK00208.
OMAAMEISAY.
OrthoDBEOG6HF644.

Enzyme and pathway databases

UniPathwayUPA00094.

Family and domain databases

Gene3D3.40.50.720. 1 hit.
InterProIPR014358. Enoyl-ACP_Rdtase_NADH.
IPR002347. Glc/ribitol_DH.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PIRSFPIRSF000094. Enoyl-ACP_rdct. 1 hit.
PRINTSPR00081. GDHRDH.
ProtoNetSearch...

Entry information

Entry nameA1AAQ6_ECOK1
AccessionPrimary (citable) accession number: A1AAQ6
Entry history
Integrated into UniProtKB/TrEMBL: January 23, 2007
Last sequence update: January 23, 2007
Last modified: June 11, 2014
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)