A1A802 (A1A802_ECOK1) Unreviewed, UniProtKB/TrEMBL
Last modified
December 14, 2011.
Version 45.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize orderNames and origin
| Protein names | Recommended name: Betaine aldehyde dehydrogenase HAMAP MF_00804 Short name=BADH HAMAP MF_00804 EC=1.2.1.8 HAMAP MF_00804 | ||||||
| Gene names |
| ||||||
| Organism | Escherichia coli O1:K1 / APEC [Complete proteome] [HAMAP] | ||||||
| Taxonomic identifier | 405955 [NCBI] | ||||||
| Taxonomic lineage | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia |
Protein attributes
| Sequence length | 491 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Catalytic activity | Betaine aldehyde + NAD+ + H2O = betaine + NADH. HAMAP MF_00804 SAAS SAAS011264 |
| Pathway | Amine and polyamine biosynthesis; betaine biosynthesis via choline pathway; betaine from betaine aldehyde: step 1/1. HAMAP MF_00804 SAAS SAAS011264 |
| Sequence similarities | Belongs to the aldehyde dehydrogenase family. RuleBase RU003345 HAMAP MF_00804 |
Ontologies
| Keywords | |
|---|---|
| Ligand | NAD HAMAP MF_00804 SAAS SAAS011264 |
| Molecular function | Oxidoreductase RuleBase RU003344 HAMAP MF_00804 SAAS SAAS011264 |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | glycine betaine biosynthetic process from choline Inferred from electronic annotation. Source: HAMAP |
| Molecular function | betaine-aldehyde dehydrogenase activity Inferred from electronic annotation. Source: HAMAP |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Regions | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Nucleotide binding | 230 – 235 | 6 | NAD By similarity HAMAP MF_00804 | ||||||
Sites | |||||||||
| Active site | 253 | 1 | By similarity HAMAP MF_00804 | ||||||
| Active site | 287 | 1 | By similarity HAMAP MF_00804 | ||||||
Sequences
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References
| [1] | "The genome sequence of avian pathogenic Escherichia coli strain O1:K1:H7 shares strong similarities with human extraintestinal pathogenic E. coli genomes." Johnson T.J., Kariyawasam S., Wannemuehler Y., Mangiamele P., Johnson S.J., Doetkott C., Skyberg J.A., Lynne A.M., Johnson J.R., Nolan L.K. J. Bacteriol. 189:3228-3236(2007) [PubMed: 17293413] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | CP000468 Genomic DNA. Translation: ABI99791.1. |
| RefSeq | YP_851506.1. NC_008563.1. |
3D structure databases | |
| ProteinModelPortal | A1A802. |
| SMR | A1A802. Positions 8-491. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | A1A802. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| EnsemblBacteria | EBESCT00000035748; EBESCP00000034265; EBESCG00000034798. |
| GeneID | 4495516. |
| GenomeReviews | Gene locus Ecok1_02980 in contig CP000468_GR. |
| KEGG | ecv:APECO1_1678. |
| PATRIC | 18212034. VBIEscCol127180_0322. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| eggNOG | COG1012. |
| GeneTree | EBGT00050000009175. |
| HOGENOM | HBG752218. |
| OMA | GRENGLM. |
| ProtClustDB | PRK13252. |
Family and domain databases | |
| HAMAP | MF_00804. BADH. [Tree] |
| InterPro | IPR016161. Ald_DH/histidinol_DH. IPR016163. Ald_DH_C. IPR016160. Ald_DH_CS. IPR016162. Ald_DH_N. IPR015590. Aldehyde_DH_dom. IPR011264. Betaine_Ald_DH. [Graphical view] |
| Gene3D | G3DSA:3.40.309.10. Aldehyde_dehydrogenase_C. 1 hit. G3DSA:3.40.605.10. Aldehyde_dehydrogenase_N. 1 hit. |
| KO | K00130. |
| Pfam | PF00171. Aldedh. 1 hit. [Graphical view] |
| SUPFAM | SSF53720. Aldehyde_DH/Histidinol_DH. 1 hit. |
| TIGRFAMs | TIGR01804. BADH. 1 hit. |
| PROSITE | PS00070. ALDEHYDE_DEHYDR_CYS. 1 hit. PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | A1A802_ECOK1 | ||||||||
| Accession | Primary (citable) accession number: A1A802 | ||||||||
| Entry history |
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| Entry status | Unreviewed (UniProtKB/TrEMBL) | ||||||||

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