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A1A7L2 (A1A7L2_ECOK1) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 45. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Methionine aminopeptidase RuleBase RU003653
EC=3.4.11.18 RuleBase RU003653
Gene names
Name:map EMBL ABI99651.1
Ordered Locus Names:Ecok1_01580
ORF Names:APECO1_1819 EMBL ABI99651.1
OrganismEscherichia coli O1:K1 / APEC [Complete proteome] [HAMAP]
Taxonomic identifier405955 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia ›

Protein attributes

Sequence length264 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Removes the N-terminal methionine from nascent proteins By similarity. RuleBase RU003653

Catalytic activity

Release of N-terminal amino acids, preferentially methionine, from peptides and arylamides. RuleBase RU003653

Cofactor

Binds 2 cobalt ions per subunit By similarity. RuleBase RU003653

Sequence similarities

Belongs to the peptidase M24A family. RuleBase RU003653

Sequences

Sequence LengthMass (Da)Tools
A1A7L2 [UniParc].

Last modified January 23, 2007. Version 1.
Checksum: F2D0B57715A67851

FASTA26429,331
        10         20         30         40         50         60 
MAISIKTPED IEKMRVAGRL AAEVLEMIEP YVKPGVSTGE LDRICNDYIV NEQHAVSACL 

        70         80         90        100        110        120 
GYHGYPKSVC ISINEVVCHG IPDDAKLLKD GDIVNIDVTV IKDGFHGDTS KMFIVGKPTI 

       130        140        150        160        170        180 
MGERLCRITQ ESLYLALRMV KPGINLREIG AAIQKFVEAE GFSVVREYCG HGIGRGFHEE 

       190        200        210        220        230        240 
PQVLHYDSRE TNVVLKPGMT FTIEPMVNAG KKEIRTMKDG WTVKTKDRSL SAQYEHTIVV 

       250        260 
TDNGCEILTL RKDDTIPAII SHDE

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References

[1]"The genome sequence of avian pathogenic Escherichia coli strain O1:K1:H7 shares strong similarities with human extraintestinal pathogenic E. coli genomes."
Johnson T.J., Kariyawasam S., Wannemuehler Y., Mangiamele P., Johnson S.J., Doetkott C., Skyberg J.A., Lynne A.M., Johnson J.R., Nolan L.K.
J. Bacteriol. 189:3228-3236(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000468 Genomic DNA. Translation: ABI99651.1.
RefSeqYP_851366.1. NC_008563.1.

3D structure databases

ProteinModelPortalA1A7L2.
SMRA1A7L2. Positions 2-264.
ModBaseSearch...

Protein-protein interaction databases

STRING405955.APECO1_1819.
A1A7L2.

Proteomic databases

PRIDEA1A7L2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABI99651; ABI99651; APECO1_1819.
GeneID4493689.
KEGGecv:APECO1_1819.
PATRIC18211731. VBIEscCol127180_0179.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0024.
HOGENOMHOG000030427.
KOK01265.
OMAGEVIQKH.
ProtClustDBPRK05716.

Family and domain databases

Gene3D3.90.230.10. 1 hit.
InterProIPR001714. Pept_M24_MAP.
IPR000994. Pept_M24_structural-domain.
IPR002467. Pept_M24A_MAP1.
[Graphical view]
PfamPF00557. Peptidase_M24. 1 hit.
[Graphical view]
PRINTSPR00599. MAPEPTIDASE.
SUPFAMSSF55920. Peptidase_M24_cat_core. 1 hit.
TIGRFAMsTIGR00500. met_pdase_I. 1 hit.
PROSITEPS00680. MAP_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

BindingDBA1A7L2.

Entry information

Entry nameA1A7L2_ECOK1
AccessionPrimary (citable) accession number: A1A7L2
Entry history
Integrated into UniProtKB/TrEMBL: January 23, 2007
Last sequence update: January 23, 2007
Last modified: May 1, 2013
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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