Unreviewed, UniProtKB/TrEMBL A1A7L2 (A1A7L2_ECOK1)

Names and origin

Protein names

Recommended name:
    Methionine aminopeptidase RuleBase RU003653V0
    EC=3.4.11.18

Gene names

Name:	map EMBL ABI99651.1
Ordered Locus Names:	Ecok1_01580
ORF Names:	APECO1_1819 EMBL ABI99651.1

Organism

Escherichia coli O1:K1 / APEC [Complete proteome] [HAMAP]

Taxonomic identifier

405955 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributes

Sequence length	264 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Removes the amino-terminal methionine from nascent proteins By similarity. RuleBase RU003653V0
Catalytic activity	Release of N-terminal amino acids, preferentially methionine, from peptides and arylamides. RuleBase RU003653V0
Cofactor	Binds 2 cobalt ions per subunit By similarity. RuleBase RU003653V0
Sequence similarities	Belongs to the peptidase M24A family. RuleBase RU003653V0

Ontologies

Keywords
Ligand	Cobalt RuleBase RU003653V0 Metal-binding RuleBase RU003653V0
Molecular function	Aminopeptidase RuleBase RU003653V0 Hydrolase Protease
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	proteolysis Inferred from electronic annotation. Source: InterPro
Molecular function	aminopeptidase activity Inferred from electronic annotation. Source: InterPro metalloexopeptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A1A7L2-1 [UniParc]. Last modified January 23, 2007. Version 1. Checksum: F2D0B57715A67851	FASTA	264	29,331
	10 20 30 40 50 60 MAISIKTPED IEKMRVAGRL AAEVLEMIEP YVKPGVSTGE LDRICNDYIV NEQHAVSACL 70 80 90 100 110 120 GYHGYPKSVC ISINEVVCHG IPDDAKLLKD GDIVNIDVTV IKDGFHGDTS KMFIVGKPTI 130 140 150 160 170 180 MGERLCRITQ ESLYLALRMV KPGINLREIG AAIQKFVEAE GFSVVREYCG HGIGRGFHEE 190 200 210 220 230 240 PQVLHYDSRE TNVVLKPGMT FTIEPMVNAG KKEIRTMKDG WTVKTKDRSL SAQYEHTIVV 250 260 TDNGCEILTL RKDDTIPAII SHDE

References

[1]

"The genome sequence of avian pathogenic Escherichia coli strain O1:K1:H7 shares strong similarities with human extraintestinal pathogenic E. coli genomes." Johnson T.J., Kariyawasam S., Wannemuehler Y., Mangiamele P., Johnson S.J., Doetkott C., Skyberg J.A., Lynne A.M., Johnson J.R., Nolan L.K. J. Bacteriol. 189:3228-3236(2007) [PubMed: 17293413] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000468 Genomic DNA. Translation: ABI99651.1.
RefSeq	YP_851366.1.
3D structure databases
SMR	A1A7L2. Positions 2-264.
ModBase	Search...
Genome annotation databases
GeneID	4493689.
GenomeReviews	Gene locus Ecok1_01580 in contig CP000468_GR.
KEGG	ecv:APECO1_1819.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	A1A7L2. VIQKHAE.
Family and domain databases
InterPro	IPR001714. Pept_M24_MAP. IPR000994. Pept_M24_structural-domain. IPR002467. Pept_M24A_MAP1. [Graphical view]
Gene3D	G3DSA:3.90.230.10. Peptidase_M24_cat_core. 1 hit.
PANTHER	PTHR10804:SF13. Pept_M24A_MAP1. 1 hit. PTHR10804. Peptidase_M24_cat_core. 1 hit.
Pfam	PF00557. Peptidase_M24. 1 hit. [Graphical view]
PRINTS	PR00599. MAPEPTIDASE.
TIGRFAMs	TIGR00500. met_pdase_I. 1 hit.
PROSITE	PS00680. MAP_1. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A1A7L2_ECOK1

Accession

Primary (citable) accession number: A1A7L2

Entry history

Integrated into UniProtKB/TrEMBL:	January 23, 2007
Last sequence update:	January 23, 2007
Last modified:	June 16, 2009
This is version 20 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)