Reviewed, UniProtKB/Swiss-Prot A1A7B0 (ARAB_ECOK1)

Names and origin

Protein names

Recommended name:
    Ribulokinase
    EC=2.7.1.16

Gene names

Name:	araB
Ordered Locus Names:	Ecok1_00560
ORF Names:	APECO1_1921

Organism

Escherichia coli O1:K1 / APEC [Complete proteome] [HAMAP]

Taxonomic identifier

405955 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributes

Sequence length	566 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + L(or D)-ribulose = ADP + L(or D)-ribulose 5-phosphate. HAMAP MF_00520
Pathway	Carbohydrate degradation; L-arabinose degradation via L-ribulose; D-xylulose 5-phosphate from L-arabinose (bacterial route): step 2/3. HAMAP MF_00520
Sequence similarities	Belongs to the ribulokinase family.

Ontologies

Keywords
Biological process	Arabinose catabolism Carbohydrate metabolism
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	L-arabinose catabolic process Inferred from electronic annotation. Source: HAMAP
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ribulokinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 566	566	Ribulokinase HAMAP MF_00520		PRO_1000050910

Sequences

	Sequence		Length	Mass (Da)
	A1A7B0-1 [UniParc]. Last modified January 23, 2007. Version 1. Checksum: D4F27FDB6D60FB77	FASTA	566	61,196
	10 20 30 40 50 60 MAIAIGLDFG SDSVRALAVD CATGEEIATS VEWYPRWQKG QFCDAPNNQF RHHPRDYIES 70 80 90 100 110 120 MEAALKTVLA ELSAEQRAAV VGIGVDTTGS TPAPIDADGN VLALRPEFAE NPNAMFVLWK 130 140 150 160 170 180 DHTAVEEAEE ITRLCHAPGN VDYSRYIGGI YSSEWFWAKI LHVTRQDSAV AQSAASWIEL 190 200 210 220 230 240 CDWVPALLSG TTRPQDIRRG RCSAGHKSLW HESWGGLPPA SFFDELDPIL NRHLPSPLFT 250 260 270 280 290 300 DTWTADIPVG TLCPEWAQRL GLPESVVISG GAFDCHMGAV GAGAQPNALV KVIGTSTCDI 310 320 330 340 350 360 LIADKQSVGE RAVKGICGQV DGSVVPGFIG LEAGQSAFGD IYAWFGRVLS WPLEQLAAQH 370 380 390 400 410 420 PELKEQINAS QKQLLPALTE AWAKNPSLDH LPVVLDWFNG RRTPNANQRL KGVITDLNLA 430 440 450 460 470 480 TDAPLLFGGL IAATAFGARA IMECFTDQGI AVNNVMALGG IARKNQVIMQ ACCDVLNRPL 490 500 510 520 530 540 QIVASDQCCA LGAAIFAAVA AKVHADIPSA QQKMASAVEK TLQPRSEQAQ RFEQLYRRYQ 550 560 QWAMSAEQHY PPTSAPAQAA QAVPTL

References

[1]

"The genome sequence of avian pathogenic Escherichia coli strain O1:K1:H7 shares strong similarities with human extraintestinal pathogenic E. coli genomes." Johnson T.J., Kariyawasam S., Wannemuehler Y., Mangiamele P., Johnson S.J., Doetkott C., Skyberg J.A., Lynne A.M., Johnson J.R., Nolan L.K. J. Bacteriol. 189:3228-3236(2007) [PubMed: 17293413] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000468 Genomic DNA. Translation: ABI99549.1.
RefSeq	YP_851264.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A1A7B0.
Genome annotation databases
GeneID	4493299.
GenomeReviews	Gene locus Ecok1_00560 in contig CP000468_GR.
KEGG	ecv:APECO1_1921.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	NGRRTPD.
Family and domain databases
HAMAP	MF_00520. [Tree]
InterPro	IPR000577. Carb_kinase_FGGY. IPR018485. Carb_kinase_FGGY_C. IPR018484. Carb_kinase_FGGY_N. IPR005929. L_ribulokin. [Graphical view]
PANTHER	PTHR10196. FGGY_kin. 1 hit.
Pfam	PF02782. FGGY_C. 1 hit. PF00370. FGGY_N. 1 hit. [Graphical view]
TIGRFAMs	TIGR01234. L-ribulokinase. 1 hit.
ProtoNet	Search...

Entry information

Entry name

ARAB_ECOK1

Accession

Primary (citable) accession number: A1A7B0

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	January 23, 2007
Last modified:	November 3, 2009
This is version 23 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)