A1A797 (A1A797_ECOK1) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Dihydrofolate reductase EMBL ABI99536.1

Gene names

Name:	folA EMBL ABI99536.1
Ordered Locus Names:	Ecok1_00430
ORF Names:	APECO1_1934 EMBL ABI99536.1

Organism

Escherichia coli O1:K1 / APEC [Complete proteome] [HAMAP]

Taxonomic identifier

405955 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia › Escherichia coli

Protein attributes

Sequence length	204 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the dihydrofolate reductase family. RuleBase RU004474

Ontologies

Keywords
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	glycine biosynthetic process Inferred from electronic annotation. Source: InterPro nucleotide biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular_function	NADP binding Inferred from electronic annotation. Source: InterPro dihydrofolate reductase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A1A797 [UniParc]. Last modified January 23, 2007. Version 1. Checksum: 6385987DDF0954D4	FASTA	204	23,212
	10 20 30 40 50 60 MRRVQGESVD SPAEYKIFLN IILAPVDDGL RFTYSGDNFF YREISMISLI AALAVDRVIG 70 80 90 100 110 120 MENAMPWNLP ADLAWFKRNT LNKPVIMGRH TWESIGRPLP GRKNIILSSQ PGTDDRVTWV 130 140 150 160 170 180 KSVDEAIAAC GDVPEIMVIG GGRVYEQFLP KAQKLYLTHI DAEVEGDTHF PDYEPDDWES 190 200 VFSEFHDADA QNSHSYCFEI LERR

References

[1]

"The genome sequence of avian pathogenic Escherichia coli strain O1:K1:H7 shares strong similarities with human extraintestinal pathogenic E. coli genomes." Johnson T.J., Kariyawasam S., Wannemuehler Y., Mangiamele P., Johnson S.J., Doetkott C., Skyberg J.A., Lynne A.M., Johnson J.R., Nolan L.K. J. Bacteriol. 189:3228-3236(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000468 Genomic DNA. Translation: ABI99536.1.
RefSeq	YP_851251.1. NC_008563.1.
3D structure databases
ProteinModelPortal	A1A797.
SMR	A1A797. Positions 46-204.
ModBase	Search...
Protein-protein interaction databases
STRING	405955.APECO1_1934.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABI99536; ABI99536; APECO1_1934.
GeneID	4493286.
KEGG	ecv:APECO1_1934.
PATRIC	18211479. VBIEscCol127180_0053.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0262.
HOGENOM	HOG000040233.
KO	K00287.
OMA	PTRFVVY.
ProtClustDB	PRK10769.
Family and domain databases
Gene3D	3.40.430.10. 1 hit.
InterPro	IPR012259. DHFR. IPR024072. DHFR-like_dom. IPR017925. DHFR_CS. IPR001796. DHFR_dom. [Graphical view]
Pfam	PF00186. DHFR_1. 1 hit. [Graphical view]
PIRSF	PIRSF000194. DHFR. 1 hit.
PRINTS	PR00070. DHFR.
SUPFAM	SSF53597. SSF53597. 1 hit.
PROSITE	PS00075. DHFR_1. 1 hit. PS51330. DHFR_2. 1 hit. [Graphical view]
ProtoNet	Search...
Other
BindingDB	A1A797.

Entry information

Entry name

A1A797_ECOK1

Accession

Primary (citable) accession number: A1A797

Entry history

Integrated into UniProtKB/TrEMBL:	January 23, 2007
Last sequence update:	January 23, 2007
Last modified:	May 1, 2013
This is version 43 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)