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Protein
Submitted name:

Coagulation factor II (Thrombin) receptor-like 1

Gene

f2rl1.1

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase, ProteaseImported, ReceptorImported

Enzyme and pathway databases

ReactomeiR-DRE-375276 Peptide ligand-binding receptors
R-DRE-416476 G alpha (q) signalling events

Names & Taxonomyi

Protein namesi
Submitted name:
Coagulation factor II (Thrombin) receptor-like 1Imported
Submitted name:
Coagulation factor II (thrombin) receptor-like 1, tandem duplicate 1Imported
Submitted name:
Putative protease-activated receptor 2aImported
Gene namesi
Name:f2rl1.1Imported
Synonyms:f2rl1Imported, PAR2aImported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 21

Organism-specific databases

ZFINiZDB-GENE-061215-140 f2rl1.1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei59 – 84HelicalSequence analysisAdd BLAST26
Transmembranei96 – 113HelicalSequence analysisAdd BLAST18
Transmembranei133 – 152HelicalSequence analysisAdd BLAST20
Transmembranei173 – 195HelicalSequence analysisAdd BLAST23
Transmembranei223 – 246HelicalSequence analysisAdd BLAST24
Transmembranei267 – 295HelicalSequence analysisAdd BLAST29
Transmembranei307 – 329HelicalSequence analysisAdd BLAST23

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Sequence analysisAdd BLAST20
ChainiPRO_501408330221 – 380Sequence analysisAdd BLAST360

Expressioni

Gene expression databases

BgeeiENSDARG00000068856

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000090506

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini75 – 326G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST252

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IGEM Eukaryota
ENOG4111CWR LUCA
GeneTreeiENSGT00910000143980
HOGENOMiHOG000116291
HOVERGENiHBG105658
KOiK04234
OMAiMAFIACI
OrthoDBiEOG091G0C2F
TreeFamiTF330775

Family and domain databases

InterProiView protein in InterPro
IPR000276 GPCR_Rhodpsn
IPR017452 GPCR_Rhodpsn_7TM
IPR002281 Pro_rcpt_2
IPR003912 Protea_act_rcpt
PfamiView protein in Pfam
PF00001 7tm_1, 1 hit
PRINTSiPR00237 GPCRRHODOPSN
PR01428 PROTEASEAR
PR01152 PROTEASEAR2
PROSITEiView protein in PROSITE
PS50262 G_PROTEIN_RECEP_F1_2, 1 hit

Sequencei

Sequence statusi: Complete.

A1A5V5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAHGLIWISA LLLFIAVNLS SQTSINPNWD RGFTGEETKE GVSVTSTALG
60 70 80 90 100
VLNSKLTQIF FPVLYIIVFS VGLPTNAMAI WVFLFRTKKK HPSSIFMANL
110 120 130 140 150
ALADLLFVIW IPLKIAYHFN GNHWIFGEAL CKVLVGFFYG NMYCSTAFIA
160 170 180 190 200
CISVQRYWAI VHPLSQQKRN NRLAVCVSVC VWLVVWALTV PLYLYDQTVK
210 220 230 240 250
VTNMDIVTCH DVTRPSQSLY PCIYFLTMGV VGFVVPCLVC IVSNVQMLRA
260 270 280 290 300
LKSSMNDPSI VQKRKKAIIL IVTVLVMFLV CFTPSNIMVM VHYALLFNGV
310 320 330 340 350
KNSGYGFYIT TLCLASLNSC VDPFVYYFIS DEFREHVRNT FLCRSERTAQ
360 370 380
RMRVSFSALK YSKKSSTYTS DSGNTQSSSY
Length:380
Mass (Da):42,889
Last modified:January 23, 2007 - v1
Checksum:iAE08A1ECE9987C7D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX323555 Genomic DNA No translation available.
BC128828 mRNA Translation: AAI28829.1
BC171395 mRNA Translation: AAI71395.1
BC171397 mRNA Translation: AAI71397.1
GQ325254 mRNA Translation: ACT98414.1
RefSeqiNP_001073273.1, NM_001079805.1
UniGeneiDr.44293

Genome annotation databases

EnsembliENSDART00000099733; ENSDARP00000090506; ENSDARG00000068856
GeneIDi794649
KEGGidre:794649

Similar proteinsi

Entry informationi

Entry nameiA1A5V5_DANRE
AccessioniPrimary (citable) accession number: A1A5V5
Entry historyiIntegrated into UniProtKB/TrEMBL: January 23, 2007
Last sequence update: January 23, 2007
Last modified: March 28, 2018
This is version 101 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health