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Protein
Submitted name:

Coagulation factor II (Thrombin) receptor-like 1

Gene

f2rl1.1

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, ProteaseImported, ReceptorImported

Enzyme and pathway databases

ReactomeiR-DRE-375276. Peptide ligand-binding receptors.
R-DRE-416476. G alpha (q) signalling events.

Names & Taxonomyi

Protein namesi
Submitted name:
Coagulation factor II (Thrombin) receptor-like 1Imported
Submitted name:
Putative protease-activated receptor 2aImported
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:f2rl1.1Imported
Synonyms:f2rl1Imported, PAR2aImported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 21

Organism-specific databases

ZFINiZDB-GENE-061215-140. f2rl1.1.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei59 – 84HelicalSequence analysisAdd BLAST26
Transmembranei96 – 113HelicalSequence analysisAdd BLAST18
Transmembranei133 – 152HelicalSequence analysisAdd BLAST20
Transmembranei173 – 195HelicalSequence analysisAdd BLAST23
Transmembranei223 – 246HelicalSequence analysisAdd BLAST24
Transmembranei267 – 295HelicalSequence analysisAdd BLAST29
Transmembranei307 – 329HelicalSequence analysisAdd BLAST23

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Sequence analysisAdd BLAST20
ChainiPRO_500875404021 – 380Sequence analysisAdd BLAST360

Expressioni

Gene expression databases

BgeeiENSDARG00000068856.

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000090506.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini75 – 326G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST252

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IGEM. Eukaryota.
ENOG4111CWR. LUCA.
GeneTreeiENSGT00760000119001.
HOGENOMiHOG000116291.
HOVERGENiHBG105658.
KOiK04234.
OMAiMAFIACI.
OrthoDBiEOG091G0C2F.
TreeFamiTF330775.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR002281. Pro_rcpt_2.
IPR003912. Protea_act_rcpt.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR01428. PROTEASEAR.
PR01152. PROTEASEAR2.
PROSITEiPS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A1A5V5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAHGLIWISA LLLFIAVNLS SQTSINPNWD RGFTGEETKE GVSVTSTALG
60 70 80 90 100
VLNSKLTQIF FPVLYIIVFS VGLPTNAMAI WVFLFRTKKK HPSSIFMANL
110 120 130 140 150
ALADLLFVIW IPLKIAYHFN GNHWIFGEAL CKVLVGFFYG NMYCSTAFIA
160 170 180 190 200
CISVQRYWAI VHPLSQQKRN NRLAVCVSVC VWLVVWALTV PLYLYDQTVK
210 220 230 240 250
VTNMDIVTCH DVTRPSQSLY PCIYFLTMGV VGFVVPCLVC IVSNVQMLRA
260 270 280 290 300
LKSSMNDPSI VQKRKKAIIL IVTVLVMFLV CFTPSNIMVM VHYALLFNGV
310 320 330 340 350
KNSGYGFYIT TLCLASLNSC VDPFVYYFIS DEFREHVRNT FLCRSERTAQ
360 370 380
RMRVSFSALK YSKKSSTYTS DSGNTQSSSY
Length:380
Mass (Da):42,889
Last modified:January 23, 2007 - v1
Checksum:iAE08A1ECE9987C7D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX323555 Genomic DNA. No translation available.
BC128828 mRNA. Translation: AAI28829.1.
BC171395 mRNA. Translation: AAI71395.1.
BC171397 mRNA. Translation: AAI71397.1.
GQ325254 mRNA. Translation: ACT98414.1.
RefSeqiNP_001073273.1. NM_001079805.1.
UniGeneiDr.44293.

Genome annotation databases

EnsembliENSDART00000099733; ENSDARP00000090506; ENSDARG00000068856.
GeneIDi794649.
KEGGidre:794649.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX323555 Genomic DNA. No translation available.
BC128828 mRNA. Translation: AAI28829.1.
BC171395 mRNA. Translation: AAI71395.1.
BC171397 mRNA. Translation: AAI71397.1.
GQ325254 mRNA. Translation: ACT98414.1.
RefSeqiNP_001073273.1. NM_001079805.1.
UniGeneiDr.44293.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000090506.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSDART00000099733; ENSDARP00000090506; ENSDARG00000068856.
GeneIDi794649.
KEGGidre:794649.

Organism-specific databases

CTDi794649.
ZFINiZDB-GENE-061215-140. f2rl1.1.

Phylogenomic databases

eggNOGiENOG410IGEM. Eukaryota.
ENOG4111CWR. LUCA.
GeneTreeiENSGT00760000119001.
HOGENOMiHOG000116291.
HOVERGENiHBG105658.
KOiK04234.
OMAiMAFIACI.
OrthoDBiEOG091G0C2F.
TreeFamiTF330775.

Enzyme and pathway databases

ReactomeiR-DRE-375276. Peptide ligand-binding receptors.
R-DRE-416476. G alpha (q) signalling events.

Gene expression databases

BgeeiENSDARG00000068856.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR002281. Pro_rcpt_2.
IPR003912. Protea_act_rcpt.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR01428. PROTEASEAR.
PR01152. PROTEASEAR2.
PROSITEiPS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiA1A5V5_DANRE
AccessioniPrimary (citable) accession number: A1A5V5
Entry historyi
Integrated into UniProtKB/TrEMBL: January 23, 2007
Last sequence update: January 23, 2007
Last modified: November 30, 2016
This is version 86 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.