SNX26

Functionⁱ

GO - Molecular functionⁱ

GTPase activator activity Source: InterPro
phosphatidylinositol binding Source: InterPro

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

protein transport Source: InterPro
signal transduction Source: InterPro

View the complete GO annotation on QuickGO ...

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: SNX26 proteinImported
Gene namesⁱ	Name:SNX26Imported
Organismⁱ	Homo sapiens (Human)Imported
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Pathology & Biotechⁱ

Organism-specific databases

PharmGKBⁱ	PA165393003

PharmGKBⁱ

PA165393003

PTM / Processingⁱ

Proteomic databases

PeptideAtlas More...PeptideAtlasⁱ	A1A5D2

PeptideAtlasⁱ

A1A5D2

Expressionⁱ

Gene expression databases

Genevisibleⁱ	A1A5D2 HS

Genevisibleⁱ

A1A5D2 HS

Interactionⁱ

Protein-protein interaction databases

IntActⁱ	A1A5D2, 1 interactor

IntActⁱ

A1A5D2, 1 interactor

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	A1A5D2
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	186 – 248	SH3InterPro annotationAdd BLAST		63
Domainⁱ	315 – 510	Rho-GAPInterPro annotationAdd BLAST		196

Keywords - Domainⁱ

SH3 domainPROSITE-ProRule annotation

Phylogenomic databases

eggNOGⁱ	KOG1449 Eukaryota ENOG41112VR LUCA
HOVERGENⁱ	HBG079688
KEGG Orthology (KO) More...KOⁱ	K17933

Family and domain databases

Gene3Dⁱ	1.10.555.10, 1 hit 3.30.1520.10, 1 hit
InterProⁱ	View protein in InterPro IPR035510 ARHGAP33 IPR036871 PX_dom_sf IPR008936 Rho_GTPase_activation_prot IPR000198 RhoGAP_dom IPR036028 SH3-like_dom_sf IPR001452 SH3_domain
PANTHERⁱ	PTHR15729:SF11 PTHR15729:SF11, 2 hits
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00620 RhoGAP, 1 hit PF14604 SH3_9, 1 hit
SMARTⁱ	View protein in SMART SM00324 RhoGAP, 1 hit SM00326 SH3, 1 hit
SUPFAMⁱ	SSF48350 SSF48350, 1 hit SSF50044 SSF50044, 1 hit SSF64268 SSF64268, 1 hit
PROSITEⁱ	View protein in PROSITE PS50238 RHOGAP, 1 hit PS50002 SH3, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

A1A5D2-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MVARSTDSLD GPGEGSVQPL PTAGGPSVKG KPGKRLSAPR GPFPRLADCA 
        60         70         80         90        100
HFHYENVDFG HIQLLLSPDR EGPSLSGENE LVFGVQVTCQ GRSWPVLRSY 
       110        120        130        140        150
DDFRSLDAHL HRCIFDRRFS CLPELPPPPE GARAAQMLVP LLLQYLETLS 
       160        170        180        190        200
GLVDSNLNCG PVLTWMELDN HGRRLLLSEE ASLNIPAVAA AHVIKRYTAQ 
       210        220        230        240        250
APDELSFEVG DIVSVIDMPP TEDRSWWRGK RGFQVGFFPS ECVELFTERP 
       260        270        280        290        300
GPGLKADADG PPCGIPAPQG ISSLTSAVPR PRGKLAGLLR TFMRSRPSRQ 
       310        320        330        340        350
RLRQRGILRQ RVFGCDLGEH LSNSGQDVPQ VLRCCSEFIE AHGVVDGIYR 
       360        370        380        390        400
LSGVSSNIQR LRHEFDSERI PELSGPAFLQ DIHSVSSLCK LYFRELPNPL 
       410        420        430        440        450
LTYQLYGKFS EAMSVPGEEE RLVRVHDVIQ QLPPPHYRTL EYLLRHLARM 
       460        470        480        490        500
ARHSANTSMH ARNLAIVWAP NLLRSMELES VGMGGAAAFR EVRVQSVVVE 
       510        520        530        540        550
FLLTHVDVLF SDTFTSAGLD PAGRCLLPRP KSLAGSCPST RLLTLEEAQA 
       560        570        580        590        600
RTQGRLGTPT EPTTPKAPAS PAERRKGERG EKQRKPGGSS WKTFFALGRG 
       610        620        630        640        650
PSVPRKKPLP WLGGTRAPPQ PSGSRPDTVT LRSAKSEESL SSQASGAGLQ 
       660        670        680        690        700
RLHRLRRPHS SSDAFPVGPA PAGSCESLSS SSSSESSSSE SSSSSSESSA 
       710        720        730        740 
AGLGALSGSP SHRTSAWLDD GDELDFSPPP YPTPSWSLHS EGQTRSYC

Length:748

Mass (Da):81,414

Last modified:January 23, 2007 - v1

Checksum:ⁱ3ADF588CD4267061

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	BC128586 mRNA Translation: AAI28587.1
NCBI Reference Sequences More...RefSeqⁱ	NP_443180.2, NM_052948.3
UniGeneⁱ	Hs.515364

Genome annotation databases

GeneIDⁱ	115703
KEGGⁱ	hsa:115703

Protein	Similar proteins		Species	Score	Length
A1A5D2	Rho GTPase activating protein 33		HORSE		744
Rho GTPase-activating protein 33		CRIGR		923
UPI00057BB3A8		CAMDR		766
Rho GTPase-activating protein 33		HUMAN		748
ARHGAP33 isoform 5		PANTR		748
+6

Protein	Similar proteins		Species	Score	Length
A1A5D2	Rho GTPase activating protein 33		HORSE		744
Rho GTPase-activating protein 33		CRIGR		923
UPI00057BB3A8		CAMDR		766
Uncharacterized protein		RHIBE		748
Rho GTPase-activating protein 33		HUMAN		748
+6

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	BC128586 mRNA Translation: AAI28587.1
NCBI Reference Sequences More...RefSeqⁱ	NP_443180.2, NM_052948.3
UniGeneⁱ	Hs.515364

3D structure databases

ProteinModelPortalⁱ	A1A5D2
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

IntActⁱ	A1A5D2, 1 interactor

IntActⁱ

A1A5D2, 1 interactor

Proteomic databases

PeptideAtlas More...PeptideAtlasⁱ	A1A5D2

PeptideAtlasⁱ

A1A5D2

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

GeneIDⁱ	115703
KEGGⁱ	hsa:115703

Organism-specific databases

CTDⁱ	115703
PharmGKBⁱ	PA165393003

Phylogenomic databases

eggNOGⁱ	KOG1449 Eukaryota ENOG41112VR LUCA
HOVERGENⁱ	HBG079688
KEGG Orthology (KO) More...KOⁱ	K17933

Miscellaneous databases

GenomeRNAiⁱ	115703

GenomeRNAiⁱ

115703

Gene expression databases

Genevisibleⁱ	A1A5D2 HS

Genevisibleⁱ

A1A5D2 HS

Family and domain databases

Gene3Dⁱ	1.10.555.10, 1 hit 3.30.1520.10, 1 hit
InterProⁱ	View protein in InterPro IPR035510 ARHGAP33 IPR036871 PX_dom_sf IPR008936 Rho_GTPase_activation_prot IPR000198 RhoGAP_dom IPR036028 SH3-like_dom_sf IPR001452 SH3_domain
PANTHERⁱ	PTHR15729:SF11 PTHR15729:SF11, 2 hits
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00620 RhoGAP, 1 hit PF14604 SH3_9, 1 hit
SMARTⁱ	View protein in SMART SM00324 RhoGAP, 1 hit SM00326 SH3, 1 hit
SUPFAMⁱ	SSF48350 SSF48350, 1 hit SSF50044 SSF50044, 1 hit SSF64268 SSF64268, 1 hit
PROSITEⁱ	View protein in PROSITE PS50238 RHOGAP, 1 hit PS50002 SH3, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	A1A5D2_HUMAN
Accessionⁱ	A1A5D2Primary (citable) accession number: A1A5D2
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	January 23, 2007
	Last sequence update:	January 23, 2007
	Last modified:	May 23, 2018
	This is version 80 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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UniProtKB - A1A5D2 (A1A5D2_HUMAN)

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SNX26 protein

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<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Cross-referencesⁱ

Entry informationⁱ