SNX26

Functionⁱ

GO - Molecular functionⁱ

phosphatidylinositol binding Source: InterPro

GO - Biological processⁱ

signal transduction Source: InterPro

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: SNX26 proteinImported
Gene namesⁱ	Name:SNX26Imported
Organismⁱ	Homo sapiens (Human)Imported
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Pathology & Biotechⁱ

Organism-specific databases

PharmGKBⁱ	PA165393003.

PharmGKBⁱ

PA165393003.

PTM / Processingⁱ

Proteomic databases

PaxDbⁱ	A1A5D2.
PeptideAtlas More...PeptideAtlasⁱ	A1A5D2.
PRIDEⁱ	A1A5D2.

Expressionⁱ

Gene expression databases

Genevisibleⁱ	A1A5D2. HS.

Genevisibleⁱ

A1A5D2. HS.

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	A1A5D2.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	186 – 248	SH3InterPro annotationAdd BLAST		63
Domainⁱ	315 – 510	Rho-GAPInterPro annotationAdd BLAST		196

Keywords - Domainⁱ

SH3 domainPROSITE-ProRule annotation

Phylogenomic databases

eggNOGⁱ	KOG1449. Eukaryota. ENOG41112VR. LUCA.
HOVERGENⁱ	HBG079688.
KEGG Orthology (KO) More...KOⁱ	K17933.

Family and domain databases

Gene3Dⁱ	3.30.1520.10. 1 hit.
InterProⁱ	View protein in InterPro IPR001683. Phox. IPR008936. Rho_GTPase_activation_prot. IPR000198. RhoGAP_dom. IPR001452. SH3_domain.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00620. RhoGAP. 1 hit. PF14604. SH3_9. 1 hit.
SMARTⁱ	View protein in SMART SM00324. RhoGAP. 1 hit. SM00326. SH3. 1 hit.
SUPFAMⁱ	SSF48350. SSF48350. 1 hit. SSF50044. SSF50044. 1 hit. SSF64268. SSF64268. 1 hit.
PROSITEⁱ	View protein in PROSITE PS50238. RHOGAP. 1 hit. PS50002. SH3. 1 hit.

Sequenceⁱ

Sequence statusⁱ: Complete.

A1A5D2-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MVARSTDSLD GPGEGSVQPL PTAGGPSVKG KPGKRLSAPR GPFPRLADCA 
        60         70         80         90        100
HFHYENVDFG HIQLLLSPDR EGPSLSGENE LVFGVQVTCQ GRSWPVLRSY 
       110        120        130        140        150
DDFRSLDAHL HRCIFDRRFS CLPELPPPPE GARAAQMLVP LLLQYLETLS 
       160        170        180        190        200
GLVDSNLNCG PVLTWMELDN HGRRLLLSEE ASLNIPAVAA AHVIKRYTAQ 
       210        220        230        240        250
APDELSFEVG DIVSVIDMPP TEDRSWWRGK RGFQVGFFPS ECVELFTERP 
       260        270        280        290        300
GPGLKADADG PPCGIPAPQG ISSLTSAVPR PRGKLAGLLR TFMRSRPSRQ 
       310        320        330        340        350
RLRQRGILRQ RVFGCDLGEH LSNSGQDVPQ VLRCCSEFIE AHGVVDGIYR 
       360        370        380        390        400
LSGVSSNIQR LRHEFDSERI PELSGPAFLQ DIHSVSSLCK LYFRELPNPL 
       410        420        430        440        450
LTYQLYGKFS EAMSVPGEEE RLVRVHDVIQ QLPPPHYRTL EYLLRHLARM 
       460        470        480        490        500
ARHSANTSMH ARNLAIVWAP NLLRSMELES VGMGGAAAFR EVRVQSVVVE 
       510        520        530        540        550
FLLTHVDVLF SDTFTSAGLD PAGRCLLPRP KSLAGSCPST RLLTLEEAQA 
       560        570        580        590        600
RTQGRLGTPT EPTTPKAPAS PAERRKGERG EKQRKPGGSS WKTFFALGRG 
       610        620        630        640        650
PSVPRKKPLP WLGGTRAPPQ PSGSRPDTVT LRSAKSEESL SSQASGAGLQ 
       660        670        680        690        700
RLHRLRRPHS SSDAFPVGPA PAGSCESLSS SSSSESSSSE SSSSSSESSA 
       710        720        730        740 
AGLGALSGSP SHRTSAWLDD GDELDFSPPP YPTPSWSLHS EGQTRSYC

Length:748

Mass (Da):81,414

Last modified:January 23, 2007 - v1

Checksum:ⁱ3ADF588CD4267061

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	BC128586 mRNA. Translation: AAI28587.1.
NCBI Reference Sequences More...RefSeqⁱ	NP_443180.2. NM_052948.3.
UniGeneⁱ	Hs.515364.

Genome annotation databases

GeneIDⁱ	115703.
KEGGⁱ	hsa:115703.

Similar proteinsⁱ

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:

100%	UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%	UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%	UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	BC128586 mRNA. Translation: AAI28587.1.
NCBI Reference Sequences More...RefSeqⁱ	NP_443180.2. NM_052948.3.
UniGeneⁱ	Hs.515364.

3D structure databases

ProteinModelPortalⁱ	A1A5D2.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Proteomic databases

PaxDbⁱ	A1A5D2.
PeptideAtlas More...PeptideAtlasⁱ	A1A5D2.
PRIDEⁱ	A1A5D2.

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

GeneIDⁱ	115703.
KEGGⁱ	hsa:115703.

Organism-specific databases

CTDⁱ	115703.
PharmGKBⁱ	PA165393003.

Phylogenomic databases

eggNOGⁱ	KOG1449. Eukaryota. ENOG41112VR. LUCA.
HOVERGENⁱ	HBG079688.
KEGG Orthology (KO) More...KOⁱ	K17933.

Miscellaneous databases

GenomeRNAiⁱ	115703.

GenomeRNAiⁱ

115703.

Gene expression databases

Genevisibleⁱ	A1A5D2. HS.

Genevisibleⁱ

A1A5D2. HS.

Family and domain databases

Gene3Dⁱ	3.30.1520.10. 1 hit.
InterProⁱ	View protein in InterPro IPR001683. Phox. IPR008936. Rho_GTPase_activation_prot. IPR000198. RhoGAP_dom. IPR001452. SH3_domain.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00620. RhoGAP. 1 hit. PF14604. SH3_9. 1 hit.
SMARTⁱ	View protein in SMART SM00324. RhoGAP. 1 hit. SM00326. SH3. 1 hit.
SUPFAMⁱ	SSF48350. SSF48350. 1 hit. SSF50044. SSF50044. 1 hit. SSF64268. SSF64268. 1 hit.
PROSITEⁱ	View protein in PROSITE PS50238. RHOGAP. 1 hit. PS50002. SH3. 1 hit.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	A1A5D2_HUMAN
Accessionⁱ	A1A5D2Primary (citable) accession number: A1A5D2
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	January 23, 2007
	Last sequence update:	January 23, 2007
	Last modified:	July 5, 2017
	This is version 74 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

UniProtKB - A1A5D2 (A1A5D2_HUMAN)

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SNX26 protein

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Pathology & Biotechⁱ

Organism-specific databases

PTM / Processingⁱ

Proteomic databases

Expressionⁱ

Gene expression databases

Structureⁱ

3D structure databases

Family & Domainsⁱ

Domains and Repeats

Keywords - Domainⁱ

Phylogenomic databases

Family and domain databases

Sequenceⁱ

Sequence databases

Genome annotation databases

Similar proteinsⁱ

Cross-referencesⁱ

Sequence databases

3D structure databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

Entry informationⁱ

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - A1A5D2 (A1A5D2_HUMAN)

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SNX26 protein

SNX26

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<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Expressionⁱ

Structureⁱ

Family & Domainsⁱ

Sequenceⁱ

Cross-referencesⁱ

Entry informationⁱ