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A1A515

- A1A515_HUMAN

UniProt

A1A515 - A1A515_HUMAN

Protein

Fibroblast growth factor

Gene

FGF8

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 45 (01 Oct 2014)
      Sequence version 1 (23 Jan 2007)
      Previous versions | rss
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    Functioni

    GO - Biological processi

    1. fibroblast growth factor receptor signaling pathway Source: InterPro

    Keywords - Molecular functioni

    Growth factorSAAS annotation

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Fibroblast growth factorUniRule annotation
    Short name:
    FGFUniRule annotation
    Gene namesi
    Name:FGF8Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Subcellular locationi

    GO - Cellular componenti

    1. extracellular region Source: InterPro

    Structurei

    3D structure databases

    ProteinModelPortaliA1A515.
    SMRiA1A515. Positions 23-169.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the heparin-binding growth factors family.UniRule annotation

    Keywords - Domaini

    SignalUniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000115986.
    HOVERGENiHBG005659.
    KOiK04358.

    Family and domain databases

    InterProiIPR008996. Cytokine_IL1-like.
    IPR028249. FGF8.
    IPR002209. Fibroblast_GF_fam.
    IPR028142. IL-1_fam/FGF_fam.
    [Graphical view]
    PANTHERiPTHR11486. PTHR11486. 1 hit.
    PTHR11486:SF3. PTHR11486:SF3. 1 hit.
    PfamiPF00167. FGF. 1 hit.
    [Graphical view]
    PRINTSiPR00262. IL1HBGF.
    SMARTiSM00442. FGF. 1 hit.
    [Graphical view]
    SUPFAMiSSF50353. SSF50353. 1 hit.
    PROSITEiPS00247. HBGF_FGF. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A1A515-1 [UniParc]FASTAAdd to Basket

    « Hide

    MGSPRSALSC LLLHLLVLCL QAQHVREQSL VTDQLSRRLI RTYQLYSRTS    50
    GKHVQVLANK RINAMAEDGD PFAKLIVETD TFGSRVRVRG AETGLYICMN 100
    KKGKLIAKSN GKGKDCVFTE IVLENNYTAL QNAKYEGWYM AFTRKGRPRK 150
    GSKTRQHQRE AHFMKRLPRG HHTTEQSLRF EFLNYPPFTR SLRGSQRTWA 200
    PEPR 204
    Length:204
    Mass (Da):23,494
    Last modified:January 23, 2007 - v1
    Checksum:i9A4CAB6524288A90
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC128236 mRNA. Translation: AAI28237.1.
    RefSeqiNP_006110.1. NM_006119.4.
    NP_149353.1. NM_033163.3.
    NP_149354.1. NM_033164.3.
    NP_149355.1. NM_033165.3.
    UniGeneiHs.57710.

    Genome annotation databases

    GeneIDi2253.
    KEGGihsa:2253.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC128236 mRNA. Translation: AAI28237.1 .
    RefSeqi NP_006110.1. NM_006119.4.
    NP_149353.1. NM_033163.3.
    NP_149354.1. NM_033164.3.
    NP_149355.1. NM_033165.3.
    UniGenei Hs.57710.

    3D structure databases

    ProteinModelPortali A1A515.
    SMRi A1A515. Positions 23-169.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 2253.
    KEGGi hsa:2253.

    Organism-specific databases

    CTDi 2253.

    Phylogenomic databases

    HOGENOMi HOG000115986.
    HOVERGENi HBG005659.
    KOi K04358.

    Miscellaneous databases

    GenomeRNAii 2253.
    NextBioi 9121.

    Family and domain databases

    InterProi IPR008996. Cytokine_IL1-like.
    IPR028249. FGF8.
    IPR002209. Fibroblast_GF_fam.
    IPR028142. IL-1_fam/FGF_fam.
    [Graphical view ]
    PANTHERi PTHR11486. PTHR11486. 1 hit.
    PTHR11486:SF3. PTHR11486:SF3. 1 hit.
    Pfami PF00167. FGF. 1 hit.
    [Graphical view ]
    PRINTSi PR00262. IL1HBGF.
    SMARTi SM00442. FGF. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50353. SSF50353. 1 hit.
    PROSITEi PS00247. HBGF_FGF. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
      , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].

    Entry informationi

    Entry nameiA1A515_HUMAN
    AccessioniPrimary (citable) accession number: A1A515
    Entry historyi
    Integrated into UniProtKB/TrEMBL: January 23, 2007
    Last sequence update: January 23, 2007
    Last modified: October 1, 2014
    This is version 45 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.