A1A490 (A1A490_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
CC chemokine receptor 5 EMBL AAY23359.1

Gene names

Name:

CCR5 EMBL AAY23359.1

Organism

Homo sapiens (Human) EMBL AAY23359.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	114 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Cellular component	Membrane
Domain	Transmembrane Transmembrane helix SAAS SAAS000355
Molecular function	G-protein coupled receptor SAAS SAAS000355 Receptor Transducer
Gene Ontology (GO)
Biological_process	chemokine-mediated signaling pathway Inferred from electronic annotation. Source: GOC chemotaxis Inferred from electronic annotation. Source: InterPro
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	chemokine receptor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	114	1	EMBL AAY23359.1

Sequences

	Sequence		Length	Mass (Da)
	A1A490 [UniParc]. Last modified January 23, 2007. Version 1. Checksum: 6726A5C03C850E12	FASTA	114	13,086
	10 20 30 40 50 60 MDYQVSSPIY DINYYTSEPC QKINVKQIAA RLLPPLYSLV FIFGFVGNML VILILINCKR 70 80 90 100 110 LKSMTDIYLL NLAISDLFFL LTAAQWDFGN TMCQLLTGLY FIGFFSGIFF IILL

References

[1]

"A novel 24-base pair deletion in the coding region of CCR5 in an African population." Masquelier C., Servais J.Y., Rusanganwa E., Roman F., Havuga E., Servais J., Tuyizere S., Omes C., Karasi J.C., Coruteille O., Karita E., Allen S., Schmit J.C., Arendt V. AIDS 21:111-113(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AY947540 Genomic DNA. Translation: AAY23359.1.
IPI	IPI00940687.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A1A490.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
HOVERGEN	HBG079402.
Gene expression databases
ArrayExpress	A1A490.
Bgee	A1A490.
Family and domain databases
InterPro	IPR000355. Chemokine_rcpt. IPR000276. GPCR_Rhodpsn. IPR017452. GPCR_Rhodpsn_7TM. [Graphical view]
Pfam	PF00001. 7tm_1. 1 hit. [Graphical view]
PRINTS	PR00657. CCCHEMOKINER. PR00237. GPCRRHODOPSN.
PROSITE	PS50262. G_PROTEIN_RECEP_F1_2. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	35460322.

Entry information

Entry name

A1A490_HUMAN

Accession

Primary (citable) accession number: A1A490

Entry history

Integrated into UniProtKB/TrEMBL:	January 23, 2007
Last sequence update:	January 23, 2007
Last modified:	May 1, 2013
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.