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A1A3X8

- RNPA_BIFAA

UniProt

A1A3X8 - RNPA_BIFAA

Protein

Ribonuclease P protein component

Gene

rnpA

Organism
Bifidobacterium adolescentis (strain ATCC 15703 / DSM 20083 / NCTC 11814 / E194a)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 51 (01 Oct 2014)
      Sequence version 1 (23 Jan 2007)
      Previous versions | rss
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    Functioni

    RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.UniRule annotation

    Catalytic activityi

    Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.UniRule annotation

    GO - Molecular functioni

    1. ribonuclease P activity Source: UniProtKB-EC
    2. tRNA binding Source: InterPro

    GO - Biological processi

    1. tRNA processing Source: UniProtKB-KW

    Keywords - Molecular functioni

    Endonuclease, Hydrolase, Nuclease

    Keywords - Biological processi

    tRNA processing

    Keywords - Ligandi

    RNA-binding

    Enzyme and pathway databases

    BioCyciBADO367928:GHPT-1701-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Ribonuclease P protein componentUniRule annotation (EC:3.1.26.5UniRule annotation)
    Short name:
    RNase P proteinUniRule annotation
    Short name:
    RNaseP proteinUniRule annotation
    Alternative name(s):
    Protein C5UniRule annotation
    Gene namesi
    Name:rnpAUniRule annotation
    Ordered Locus Names:BAD_1630
    OrganismiBifidobacterium adolescentis (strain ATCC 15703 / DSM 20083 / NCTC 11814 / E194a)
    Taxonomic identifieri367928 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeBifidobacterialesBifidobacteriaceaeBifidobacterium
    ProteomesiUP000008702: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 121121Ribonuclease P protein componentPRO_1000021377Add
    BLAST

    Interactioni

    Subunit structurei

    Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.UniRule annotation

    Protein-protein interaction databases

    STRINGi367928.BAD_1630.

    Structurei

    3D structure databases

    ProteinModelPortaliA1A3X8.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the RnpA family.UniRule annotation

    Phylogenomic databases

    eggNOGiNOG85700.
    HOGENOMiHOG000266301.
    KOiK03536.
    OMAiMLPAQHK.
    OrthoDBiEOG6C01C6.

    Family and domain databases

    Gene3Di3.30.230.10. 1 hit.
    HAMAPiMF_00227. RNase_P.
    InterProiIPR020568. Ribosomal_S5_D2-typ_fold.
    IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
    IPR000100. RNase_P.
    [Graphical view]
    PfamiPF00825. Ribonuclease_P. 1 hit.
    [Graphical view]
    ProDomiPD003629. Ribonuclease_P. 1 hit.
    [Graphical view] [Entries sharing at least one domain]
    SUPFAMiSSF54211. SSF54211. 1 hit.
    TIGRFAMsiTIGR00188. rnpA. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    A1A3X8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MERLKSHRDF VAVLKRRRRV SREDIVVHYL MHDDVVTGDT ATVQGRRVGL    50
    AVSKAVGNAV TRNAVKRRFR VLARKYESLL PESCDIVLRA KPSAARADFL 100
    SLEQQMASCF EAVKRKTASR Q 121
    Length:121
    Mass (Da):13,753
    Last modified:January 23, 2007 - v1
    Checksum:i84F4E86409AB59A0
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP009256 Genomic DNA. Translation: BAF40411.1.
    RefSeqiWP_003807160.1. NC_008618.1.
    YP_910493.1. NC_008618.1.

    Genome annotation databases

    EnsemblBacteriaiBAF40411; BAF40411; BAD_1630.
    GeneIDi4556667.
    KEGGibad:BAD_1630.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP009256 Genomic DNA. Translation: BAF40411.1 .
    RefSeqi WP_003807160.1. NC_008618.1.
    YP_910493.1. NC_008618.1.

    3D structure databases

    ProteinModelPortali A1A3X8.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 367928.BAD_1630.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAF40411 ; BAF40411 ; BAD_1630 .
    GeneIDi 4556667.
    KEGGi bad:BAD_1630.

    Phylogenomic databases

    eggNOGi NOG85700.
    HOGENOMi HOG000266301.
    KOi K03536.
    OMAi MLPAQHK.
    OrthoDBi EOG6C01C6.

    Enzyme and pathway databases

    BioCyci BADO367928:GHPT-1701-MONOMER.

    Family and domain databases

    Gene3Di 3.30.230.10. 1 hit.
    HAMAPi MF_00227. RNase_P.
    InterProi IPR020568. Ribosomal_S5_D2-typ_fold.
    IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
    IPR000100. RNase_P.
    [Graphical view ]
    Pfami PF00825. Ribonuclease_P. 1 hit.
    [Graphical view ]
    ProDomi PD003629. Ribonuclease_P. 1 hit.
    [Graphical view ] [Entries sharing at least one domain ]
    SUPFAMi SSF54211. SSF54211. 1 hit.
    TIGRFAMsi TIGR00188. rnpA. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Bifidobacterium adolescentis complete genome sequence."
      Suzuki T., Tsuda Y., Kanou N., Inoue T., Kumazaki K., Nagano S., Hirai S., Tanaka K., Watanabe K.
      Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 15703 / DSM 20083 / NCTC 11814 / E194a.

    Entry informationi

    Entry nameiRNPA_BIFAA
    AccessioniPrimary (citable) accession number: A1A3X8
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 15, 2008
    Last sequence update: January 23, 2007
    Last modified: October 1, 2014
    This is version 51 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3