Reviewed, UniProtKB/Swiss-Prot A1A3A8 (ARAA_BIFAA)

Names and origin

Protein names

Recommended name:
    L-arabinose isomerase
    EC=5.3.1.4

Gene names

Name:	araA
Ordered Locus Names:	BAD_1410

Organism

Bifidobacterium adolescentis (strain ATCC 15703 / DSM 20083) [Complete proteome] [HAMAP]

Taxonomic identifier

367928 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Bifidobacteriales › Bifidobacteriaceae › Bifidobacterium

Protein attributes

Sequence length	504 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the conversion of L-arabinose to L-ribulose By similarity.
Catalytic activity	L-arabinose = L-ribulose. HAMAP MF_00519
Cofactor	Binds 1 manganese ion per subunit By similarity.
Pathway	Carbohydrate degradation; L-arabinose degradation via L-ribulose; D-xylulose 5-phosphate from L-arabinose (bacterial route): step 1/3. HAMAP MF_00519
Sequence similarities	Belongs to the arabinose isomerase family.

Ontologies

Keywords
Biological process	Arabinose catabolism Carbohydrate metabolism
Ligand	Manganese Metal-binding
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	arabinose catabolic process Inferred from electronic annotation. Source: HAMAP
Molecular function	L-arabinose isomerase activity Inferred from electronic annotation. Source: HAMAP manganese ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 504	504	L-arabinose isomerase HAMAP MF_00519		PRO_0000312603
Sites
	Metal binding	308	1	Manganese By similarity
	Metal binding	335	1	Manganese By similarity
	Metal binding	352	1	Manganese By similarity
	Metal binding	452	1	Manganese By similarity

Sequences

	Sequence		Length	Mass (Da)
	A1A3A8-1 [UniParc]. Last modified January 23, 2007. Version 1. Checksum: FD2E93AD90377119	FASTA	504	55,884
	10 20 30 40 50 60 MAMENPFEGK EIWFGVGSQD LYGEEALRQV AQQTGEMVDF LNATGKIPAK IVLKPTLKSS 70 80 90 100 110 120 DGVKAFMTEA SANPNVIGVI TWCHTFSPAK MWIRGLEVLT KPLLQLATQH HKEIPWETID 130 140 150 160 170 180 MDFMNLNQAA HGDREFGYIV SRLGIPRKIV VGHYTDPEVA EKVGTWARAC AGWDASQNMK 190 200 210 220 230 240 VMRWGDNMRN VAVTEGDKTE AERVFGASIN TWAVNDLVAA YEKVKDSQVK DLIEDYKAKY 250 260 270 280 290 300 DVAPELLDSR YDELFIAAKE EAAMVNMMRE NGCTAGVDNF EDLGTLPQLP GVGPQRFPSE 310 320 330 340 350 360 YGWGFSAEGD WKTSVLVRIG AVMGYGLEGG ASLMEDYSYN FVPGNEFDMG SHMLEVSPSI 370 380 390 400 410 420 GTIAKPKLAI YPLGIGGKSD PVRLVFSGKP ADAVVVSMAD ERERFRLLMD EVTIVEPQGS 430 440 450 460 470 480 LKNLPCARAV WKPKPDLKTA VQCWITAGGS HHTCMTTSVG REAWEDFARI AGVELAVIDE 490 500 NTNARQFEKE LELSEMYHRL NNRH

References

[1]	"Bifidobacterium adolescentis complete genome sequence." Suzuki T., Tsuda Y., Kanou N., Inoue T., Kumazaki K., Nagano S., Hirai S., Tanaka K., Watanabe K. Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	AP009256 Genomic DNA. Translation: BAF40191.1.
RefSeq	YP_910273.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A1A3A8.
Genome annotation databases
GeneID	4557387.
GenomeReviews	Gene locus BAD_1410 in contig AP009256_GR.
KEGG	bad:BAD_1410.
NMPDR	fig|1680.3.peg.1027.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	EVCPTIA.
Family and domain databases
HAMAP	MF_00519. [Tree]
InterPro	IPR003762. Lara_isomerase. [Graphical view]
Pfam	PF02610. Arabinose_Isome. 1 hit. [Graphical view]
PIRSF	PIRSF001478. L-ara_isomerase. 1 hit.
ProDom	PD018364. Lara_isomerase. 1 hit. [Graphical view] [Entries sharing at least one domain]
ProtoNet	Search...

Entry information

Entry name

ARAA_BIFAA

Accession

Primary (citable) accession number: A1A3A8

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 4, 2007
Last sequence update:	January 23, 2007
Last modified:	November 3, 2009
This is version 20 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)