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A1A332 (A1A332_BIFAA) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 40. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesSubmitted name:
Dihydroorotate dehydrogenase-like protein EMBL BAF40115.1
Gene names
Ordered Locus Names:BAD_1334
OrganismBifidobacterium adolescentis (strain ATCC 15703 / DSM 20083 / NCTC 11814 / E194a) [Complete proteome] [HAMAP]
Taxonomic identifier367928 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Bifidobacteriales › Bifidobacteriaceae › Bifidobacterium

Protein attributes

Sequence length337 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor By similarity. SAAS SAAS012135

Catalytic activity

(S)-dihydroorotate + a quinone = orotate + a quinol. SAAS SAAS012135

Cofactor

Binds 1 FMN per subunit By similarity. SAAS SAAS012135

Pathway

Pyrimidine metabolism; UMP biosynthesis via de novo pathway; orotate from (S)-dihydroorotate (quinone route): step 1/1. SAAS SAAS012135

Subunit structure

Monomer By similarity. SAAS SAAS012135

Ontologies

Keywords
   Biological processPyrimidine biosynthesis SAAS SAAS012135
   Cellular componentMembrane SAAS SAAS012135
   LigandFMN SAAS SAAS012135
Flavoprotein SAAS SAAS012135
   Molecular functionOxidoreductase SAAS SAAS012135
   Technical termComplete proteome
Gene Ontology (GO)
   Biological process'de novo' pyrimidine base biosynthetic process

Inferred from electronic annotation. Source: InterPro

UMP biosynthetic process

Inferred from electronic annotation. Source: InterPro

   Cellular componentmembrane

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functiondihydroorotate oxidase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site1651Nucleophile By similarity PIRSR PIRSR000164-1

Sequences

Sequence LengthMass (Da)Tools
A1A332 [UniParc].

Last modified January 23, 2007. Version 1.
Checksum: 1CBEB747819A82E3

FASTA33737,395
        10         20         30         40         50         60 
MIDFCKVTRN IPPLMWLCRE MLDYTDPILE TNVMGVDFAN PFGLSAGLDK DCEMPVLLDN 

        70         80         90        100        110        120 
VGFGFETVGS TTSRPCPGNP RPWFHRLPEY DSMMVHVGLA NEGSAVVIPR AENAWTKAKS 

       130        140        150        160        170        180 
MQVSVSIART NDSKTGDLDE GIEDYCISMR RAAGRTAMVE VNISCPNTMA GEPFNQSPEA 

       190        200        210        220        230        240 
LDKLFTELDK IDRPQPTLVK MPLNKTWPEF KDLLDVLAEH NVQGLSIANL QKDRTGMSIP 

       250        260        270        280        290        300 
RDWEGGLSGS PCYATSNERI KQVYREYGDR FAIAGIGGVF TPQQAYEKIR CGSSLVMFIS 

       310        320        330 
ALMYRGPQQI TVLKRGLAEL LRRDGFEHVS EAVGIDA

« Hide

References

[1]"Bifidobacterium adolescentis complete genome sequence."
Suzuki T., Tsuda Y., Kanou N., Inoue T., Kumazaki K., Nagano S., Hirai S., Tanaka K., Watanabe K.
Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 15703 / DSM 20083 / NCTC 11814 / E194a.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP009256 Genomic DNA. Translation: BAF40115.1.
RefSeqYP_910197.1. NC_008618.1.

3D structure databases

ProteinModelPortalA1A332.
ModBaseSearch...

Protein-protein interaction databases

STRINGA1A332.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4557459.
GenomeReviewsGene locus BAD_1334 in contig AP009256_GR.
KEGGbad:BAD_1334.
NMPDRfig|1680.3.peg.966.
PATRIC21102121. VBIBifAdo27973_1415.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0167.
HOGENOMHBG351027.
OMASYVTVNI.
ProtClustDBPRK05286.

Family and domain databases

InterProIPR013785. Aldolase_TIM.
IPR012135. Dihydroorotate_DH_1_2.
IPR005719. Dihydroorotate_DH_2.
[Graphical view]
Gene3DG3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KOK00226.
PfamPF01180. DHO_dh. 1 hit.
[Graphical view]
PIRSFPIRSF000164. DHO_oxidase. 1 hit.
TIGRFAMsTIGR01036. PyrD_sub2. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA1A332_BIFAA
AccessionPrimary (citable) accession number: A1A332
Entry history
Integrated into UniProtKB/TrEMBL: January 23, 2007
Last sequence update: January 23, 2007
Last modified: December 14, 2011
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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