Reviewed, UniProtKB/Swiss-Prot A1A2Z2 (GLMM_BIFAA)

Names and origin

Protein names

Recommended name:
    Phosphoglucosamine mutase
    EC=5.4.2.10

Gene names

Name:	glmM
Ordered Locus Names:	BAD_1294

Organism

Bifidobacterium adolescentis (strain ATCC 15703 / DSM 20083) [Complete proteome] [HAMAP]

Taxonomic identifier

367928 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Bifidobacteriales › Bifidobacteriaceae › Bifidobacterium

Protein attributes

Sequence length	459 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate By similarity.
Catalytic activity	Alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate. HAMAP MF_01554
Cofactor	Binds 1 magnesium ion per subunit By similarity.
Post-translational modification	Activated by phosphorylation By similarity.
Sequence similarities	Belongs to the phosphohexose mutase family.

Ontologies

Keywords
Ligand	Magnesium Metal-binding
Molecular function	Isomerase
PTM	Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	magnesium ion binding Inferred from electronic annotation. Source: UniProtKB-KW phosphoglucosamine mutase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 459	459	Phosphoglucosamine mutase HAMAP MF_01554		PRO_0000301282
Sites
	Active site	105	1	Phosphoserine intermediate By similarity
	Metal binding	105	1	Magnesium; via phosphate group By similarity
	Metal binding	252	1	Magnesium By similarity
	Metal binding	254	1	Magnesium By similarity
	Metal binding	256	1	Magnesium By similarity
Amino acid modifications
	Modified residue	105	1	Phosphoserine By similarity

Sequences

	Sequence		Length	Mass (Da)
	A1A2Z2-1 [UniParc]. Last modified January 23, 2007. Version 1. Checksum: 4C84EB727F35D653	FASTA	459	48,355
	10 20 30 40 50 60 MPRMFGTDGV RGLANRDLTA QLALDLGDAA VRVLGDDERS EFESRRRALV GRDTRVSGDF 70 80 90 100 110 120 LAAALSAGMS AGGFDVIDAG IIPTPGVAYL TSVLNVEMGA VISASHNPMP DNGIKFFARG 130 140 150 160 170 180 GFKLPDTKED EIEAVLGQDW DRPTGAGVGR VSHDTATATN LYIDHLVSAI APVGPDKSQP 190 200 210 220 230 240 TPLKGLKIVA DCANGATSVV APEALRRAGA DVTVINASPD GYNINKNAGS THPEQLQAMV 250 260 270 280 290 300 KASGAVMGVA FDGDADRCLA VDEDGNMVNG DQIMGILARA KKNAGKLNHD TLVVTVMSNL 310 320 330 340 350 360 GLKLALRSMG IKTVQTNVGD RYVLEEMLRG DYSLGGEQSG HVINREFATT GDGTLTALTL 370 380 390 400 410 420 CNEVVKSGKS LKELAADFPQ LPQTLINVPN VDKMAAKTNA KVQAAVEREE KLLGDTGRVL 430 440 450 LRPSGTEPLV RVMAEAETQQ QADEVCDRLA KVVADELTL

References

[1]	"Bifidobacterium adolescentis complete genome sequence." Suzuki T., Tsuda Y., Kanou N., Inoue T., Kumazaki K., Nagano S., Hirai S., Tanaka K., Watanabe K. Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	AP009256 Genomic DNA. Translation: BAF40075.1.
RefSeq	YP_910157.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A1A2Z2.
Genome annotation databases
GeneID	4556422.
GenomeReviews	Gene locus BAD_1294 in contig AP009256_GR.
KEGG	bad:BAD_1294.
NMPDR	fig|1680.3.peg.924.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	AHAVGRV.
Family and domain databases
HAMAP	MF_01554. [Tree]
InterPro	IPR005844. A-D-PHexomutase_a/b/a-I. IPR016055. A-D-PHexomutase_a/b/a-I/II/III. IPR005845. A-D-PHexomutase_a/b/a-II. IPR005846. A-D-PHexomutase_a/b/a-III. IPR005843. A-D-PHexomutase_C. IPR016066. A-D-PHexomutase_CS. IPR005841. A-D-PHexomutase_N. IPR006352. GlmM. [Graphical view]
Gene3D	G3DSA:3.40.120.10. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
Pfam	PF02878. PGM_PMM_I. 1 hit. PF02879. PGM_PMM_II. 1 hit. PF02880. PGM_PMM_III. 1 hit. PF00408. PGM_PMM_IV. 1 hit. [Graphical view]
PRINTS	PR00509. PGMPMM.
TIGRFAMs	TIGR01455. glmM. 1 hit.
PROSITE	PS00710. PGM_PMM. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLMM_BIFAA

Accession

Primary (citable) accession number: A1A2Z2

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 11, 2007
Last sequence update:	January 23, 2007
Last modified:	November 3, 2009
This is version 25 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)