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Protein

Cell division protein FtsZ

Gene

ftsZ

Organism
Bifidobacterium adolescentis (strain ATCC 15703 / DSM 20083 / NCTC 11814 / E194a)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei142GTPUniRule annotation1
Binding sitei146GTPUniRule annotation1
Binding sitei190GTPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi24 – 28GTPUniRule annotation5
Nucleotide bindingi111 – 113GTPUniRule annotation3

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processCell cycle, Cell division, SeptationUniRule annotation
LigandGTP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciBADO367928:G1G2R-1225-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Cell division protein FtsZUniRule annotation
Gene namesi
Name:ftsZUniRule annotationImported
Ordered Locus Names:BAD_1136Imported
OrganismiBifidobacterium adolescentis (strain ATCC 15703 / DSM 20083 / NCTC 11814 / E194a)Imported
Taxonomic identifieri367928 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaBifidobacterialesBifidobacteriaceaeBifidobacterium
Proteomesi
  • UP000008702 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi367928.BAD_1136

Structurei

3D structure databases

ProteinModelPortaliA1A2I4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini16 – 208TubulinInterPro annotationAdd BLAST193
Domaini210 – 327Tubulin_CInterPro annotationAdd BLAST118

Sequence similaritiesi

Belongs to the FtsZ family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CDK Bacteria
COG0206 LUCA
HOGENOMiHOG000049094
KOiK03531
OMAiMRAVKGI
OrthoDBiPOG091H02KK

Family and domain databases

CDDicd02201 FtsZ_type1, 1 hit
Gene3Di3.30.1330.20, 1 hit
3.40.50.1440, 1 hit
HAMAPiMF_00909 FtsZ, 1 hit
InterProiView protein in InterPro
IPR000158 Cell_div_FtsZ
IPR020805 Cell_div_FtsZ_CS
IPR024757 FtsZ_C
IPR008280 Tub_FtsZ_C
IPR018316 Tubulin/FtsZ_2-layer-sand-dom
IPR037103 Tubulin/FtsZ_C_sf
IPR036525 Tubulin/FtsZ_GTPase_sf
IPR003008 Tubulin_FtsZ_GTPase
PfamiView protein in Pfam
PF12327 FtsZ_C, 1 hit
PF00091 Tubulin, 1 hit
PRINTSiPR00423 CELLDVISFTSZ
SMARTiView protein in SMART
SM00864 Tubulin, 1 hit
SM00865 Tubulin_C, 1 hit
SUPFAMiSSF52490 SSF52490, 1 hit
SSF55307 SSF55307, 1 hit
TIGRFAMsiTIGR00065 ftsZ, 1 hit
PROSITEiView protein in PROSITE
PS01135 FTSZ_2, 1 hit

Sequencei

Sequence statusi: Complete.

A1A2I4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVSEIAQTDN FNDKTNIKVV GVGGAGGNAV NRMIAEGLQS VEFIAINTDA
60 70 80 90 100
KDLLRSDADV KISLNDASSR GLGAGADPEK GAKAAQDHQS DIEEALKGSD
110 120 130 140 150
MVFVTCGEGG GTGTGASPIV ARAAHQQGAL TIAVVTRPFS FEGPQRSASA
160 170 180 190 200
ALGIENLRKE VDALIVIPND RLLELSDRTI GIVDAFKTAD TALLAGVQGI
210 220 230 240 250
TDLITSNSYI HVDFNDVNAI LRGAGTALFG IGSARGEDRA TQAAEIAISS
260 270 280 290 300
PLLEESIEGA HGALINIAGP TDLKLQEAAA AVALVQKAIH PEAQIIWGLS
310 320 330 340 350
LDDAYGDEVR VTVIAAGFDA NSKKPDQPAE EKPAAAKGNT VPLSALSAGV
360 370 380 390 400
QAPAQQPQPV QTPAVPQVQP LSSYIPSTPD QNVASFDQTT EHEVVSANDP
410
GDLDIPDFLR
Length:410
Mass (Da):42,374
Last modified:January 23, 2007 - v1
Checksum:i8D46C07BC1AD7530
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP009256 Genomic DNA Translation: BAF39917.1
RefSeqiWP_011743471.1, NC_008618.1

Genome annotation databases

EnsemblBacteriaiBAF39917; BAF39917; BAD_1136
GeneIDi4557237
KEGGibad:BAD_1136

Similar proteinsi

Entry informationi

Entry nameiA1A2I4_BIFAA
AccessioniPrimary (citable) accession number: A1A2I4
Entry historyiIntegrated into UniProtKB/TrEMBL: January 23, 2007
Last sequence update: January 23, 2007
Last modified: March 28, 2018
This is version 87 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health