A1A2H8 (A1A2H8_BIFAA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
DNA polymerase III alpha subunit EMBL BAF39911.1

Gene names

Name:	dnaE1 EMBL BAF39911.1
Ordered Locus Names:	BAD_1130

Organism

Bifidobacterium adolescentis (strain ATCC 15703 / DSM 20083 / NCTC 11814 / E194a) [Complete proteome] [HAMAP]

Taxonomic identifier

367928 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Bifidobacteriales › Bifidobacteriaceae › Bifidobacterium

Protein attributes

Sequence length	1196 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Catalytic activity

Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). SAAS SAAS004013

Ontologies

Keywords
Biological process	DNA replication SAAS SAAS004013
Cellular component	Cytoplasm SAAS SAAS004013
Molecular function	DNA-directed DNA polymerase SAAS SAAS004013 Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA replication Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	3'-5' exonuclease activity Inferred from electronic annotation. Source: InterPro DNA binding Inferred from electronic annotation. Source: InterPro DNA-directed DNA polymerase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A1A2H8 [UniParc]. Last modified January 23, 2007. Version 1. Checksum: 8DE921D0205F0BA1	FASTA	1,196	132,702
	10 20 30 40 50 60 MATSANFVQL HNHTHYSLLD GASKIPDLVK RAKELGMPAV GITDHGNMHG AYEMWSAAVN 70 80 90 100 110 120 AGIKPIIGIE AYVTPETARQ DPTRVSWDTN WNPDLDPLHR RRNPDDVSGG GVITHLTMWA 130 140 150 160 170 180 ENDEGLVNLM KASTDANLEG RVMRYPRMDK EILAKYSKGI IASSGCPSGI IQTRLRLGQF 190 200 210 220 230 240 DDALRAAGEF QDIFGRDNFY IEFMDHGLKI EKQVTDGLLD IAKKLNAPLL ATNDSHYTRA 250 260 270 280 290 300 EDAGAQDAML CINSGSTLDE PGRFKFDGTG YYIKSAEEMR ELFKDLPEAC DNTLEIAERC 310 320 330 340 350 360 NVMFDDHEDG AFMPQFDCPE GWDETSLFLK KVEEGLERRY NGKPSLEVLR QADYECGVIC 370 380 390 400 410 420 QMQFCGYFLV VADYINWAKA HGVMVGPGRG SAAGAMVAYA MGITELDPLE HGLIFERFLN 430 440 450 460 470 480 PERVSLPDID VDFDPDGRGR VLDYVGEKYG RDKVAQCVIY GTIKTKQALK DSARIMGYDF 490 500 510 520 530 540 SVGDKITKAL PPAQTGGKDI PLHDIFDPSA KRYAEAREFR ELYDSDPDTK RITDEAMGIE 550 560 570 580 590 600 GLIRQTGVHA CATIMGSEPI TNTSPLLERT DGTVTTTLEY HTCETLGLVK MDFLGLSNLT 610 620 630 640 650 660 VIRDTLNNIE ANGKERIDHT KIPLDDRPTY DLLSRGDTLG VFQLDSDGMR SLLKTLKPNN 670 680 690 700 710 720 FNDISALIAL YRPGPMDMDS HTNYAKRKNG LQKITPIHPE VAEPLKEVLD ETYGLIVYQE 730 740 750 760 770 780 QVQSAARILA GYSLGKADVL RRAMGKKKPE VLAKEKIPFF AGMKEHGYSE EAAQAVWDIL 790 800 810 820 830 840 VPFSGYAFNK AHSAAYGLIS YWTAYLKTHY PVEFMAALLQ GASTNKDKTA LYLGEARRMG 850 860 870 880 890 900 IQVLSPDVNE SVYEYSAVGD VVRFGLGAIR NVGKNAVDAI IAERENGHGK YVNFTDFIKR 910 920 930 940 950 960 VPLEALNRRL VESLIKAGAF DSIDPNRRAL FTIHETAINS VVGLKRKQAE GQFDLFADLD 970 980 990 1000 1010 1020 DSKENDSAMG DAMVQVPDVE EWDKKTKLNF EREMLGLYVS DHPLSGMQSI LVSLREMSIA 1030 1040 1050 1060 1070 1080 HLIDRAGSMP DGQQVTIAGL ITNVDRRVSK KGNPWAIVTV EDLESSIQCM FFGKVYEAAA 1090 1100 1110 1120 1130 1140 PELAVDTVVQ IRGQVEKRDE TVSMRATEFT VPTLEAQDER PLTIVLPPIA LDQSHVRRLG 1150 1160 1170 1180 1190 QILTSHPGPC EVKLALMDDK GNAKVLTFGD RFRVKRDTSL FAEIKILFGP SSLPLA

References

[1]

"Bifidobacterium adolescentis complete genome sequence." Suzuki T., Tsuda Y., Kanou N., Inoue T., Kumazaki K., Nagano S., Hirai S., Tanaka K., Watanabe K. Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 15703 / DSM 20083 / NCTC 11814 / E194a.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP009256 Genomic DNA. Translation: BAF39911.1.
RefSeq	YP_909993.1. NC_008618.1.
3D structure databases
ProteinModelPortal	A1A2H8.
ModBase	Search...
Protein-protein interaction databases
STRING	A1A2H8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4556252.
GenomeReviews	Gene locus BAD_1130 in contig AP009256_GR.
KEGG	bad:BAD_1130.
NMPDR	fig|1680.3.peg.154.
PATRIC	21101693. VBIBifAdo27973_1210.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0587.
HOGENOM	HBG734490.
OMA	RVLQMPY.
ProtClustDB	PRK05673.
Family and domain databases
InterPro	IPR011708. DNA_pol3_alpha. IPR012340. NA-bd_OB-fold. IPR004365. NA-bd_OB_tRNA-helicase. IPR004013. PHP_C. IPR003141. Pol/His_phosphatase_N. IPR016195. Pol/histidinol_Pase-like. IPR004805. PolC_alpha. [Graphical view]
Gene3D	G3DSA:2.40.50.140. OB_NA_bd_sub. 1 hit.
KO	K02337.
Pfam	PF07733. DNA_pol3_alpha. 1 hit. PF02811. PHP. 1 hit. PF01336. tRNA_anti. 1 hit. [Graphical view]
SMART	SM00481. POLIIIAc. 1 hit. [Graphical view]
SUPFAM	SSF89550. PHP-like. 1 hit.
TIGRFAMs	TIGR00594. Polc. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A1A2H8_BIFAA

Accession

Primary (citable) accession number: A1A2H8

Entry history

Integrated into UniProtKB/TrEMBL:	January 23, 2007
Last sequence update:	January 23, 2007
Last modified:	December 14, 2011
This is version 36 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)