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A1A1G2 (A1A1G2_BIFAA) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 46. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Dihydroorotate dehydrogenase HAMAP MF_00224
Short name=DHOD HAMAP MF_00224
Short name=DHODase HAMAP MF_00224
Short name=DHOdehase HAMAP MF_00224
EC=1.3.-.- HAMAP MF_00224
Gene names
Name:pyrD HAMAP MF_00224 EMBL BAF39545.1
Ordered Locus Names:BAD_0764
OrganismBifidobacterium adolescentis (strain ATCC 15703 / DSM 20083 / NCTC 11814 / E194a) [Complete proteome] [HAMAP]
Taxonomic identifier367928 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Bifidobacteriales › Bifidobacteriaceae › Bifidobacterium

Protein attributes

Sequence length315 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the conversion of dihydroorotate to orotate By similarity. HAMAP MF_00224

Catalytic activity

(S)-dihydroorotate + acceptor = orotate + reduced acceptor. HAMAP MF_00224

Cofactor

Binds 1 FMN per subunit By similarity. HAMAP MF_00224 SAAS SAAS012135

Pathway

Pyrimidine metabolism; UMP biosynthesis via de novo pathway. HAMAP MF_00224

Subcellular location

Cytoplasm By similarity HAMAP MF_00224.

Sequence similarities

Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily. HAMAP MF_00224

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site1411Nucleophile By similarity PIRSR PIRSR000164-1

Sequences

Sequence LengthMass (Da)Tools
A1A1G2 [UniParc].

Last modified January 23, 2007. Version 1.
Checksum: 20F38156B05A53A6

FASTA31533,405
        10         20         30         40         50         60 
MTAEQHANLY EQHEWKHPTQ VAGIPWKNPV ATASGTFQYA AVRWFYDVSQ LGAVTTKGVS 

        70         80         90        100        110        120 
PVPWEGNPGI RTAEGPSSNI NAVGLQNPGV DHYLEDDLPK LKAINATVIA NVAGHCDDDY 

       130        140        150        160        170        180 
AEVVSKLDDS PADMLEINVS CPNVSAGGMS VGTDPVALSR LITRLRKLTD KKMIVKLTPN 

       190        200        210        220        230        240 
VTDITVPARA AVESGADALS LINTLLGMRI NIRTGEPVIT HVTGGVSGPA VLPVGLAAVW 

       250        260        270        280        290        300 
RVRAALPEIP IIGIGGIDSG ETALEYLYAG ANAVEVGAAA LFEPTAPLRV ARELDDLLDE 

       310 
RPELADKLAK GETWR

« Hide

References

[1]"Bifidobacterium adolescentis complete genome sequence."
Suzuki T., Tsuda Y., Kanou N., Inoue T., Kumazaki K., Nagano S., Hirai S., Tanaka K., Watanabe K.
Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 15703 / DSM 20083 / NCTC 11814 / E194a.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP009256 Genomic DNA. Translation: BAF39545.1.
RefSeqYP_909627.1. NC_008618.1.

3D structure databases

ProteinModelPortalA1A1G2.
ModBaseSearch...

Protein-protein interaction databases

STRINGA1A1G2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4556607.
GenomeReviewsGene locus BAD_0764 in contig AP009256_GR.
KEGGbad:BAD_0764.
NMPDRfig|1680.3.peg.1346.
PATRIC21100911. VBIBifAdo27973_0830.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0167.
HOGENOMHBG472415.
OMAVALRMVW.
ProtClustDBCLSK572774.

Family and domain databases

HAMAPMF_00224. DHO_dh_type1.
[Tree]
InterProIPR013785. Aldolase_TIM.
IPR005720. Dihydroorotate_DH.
IPR024920. Dihydroorotate_DH_1.
IPR012135. Dihydroorotate_DH_1_2.
IPR001295. Dihydroorotate_DH_CS.
[Graphical view]
Gene3DG3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KOK00226.
PfamPF01180. DHO_dh. 1 hit.
[Graphical view]
PIRSFPIRSF000164. DHO_oxidase. 1 hit.
TIGRFAMsTIGR01037. PyrD_sub1_fam. 1 hit.
PROSITEPS00912. DHODEHASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA1A1G2_BIFAA
AccessionPrimary (citable) accession number: A1A1G2
Entry history
Integrated into UniProtKB/TrEMBL: January 23, 2007
Last sequence update: January 23, 2007
Last modified: January 25, 2012
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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