A1A1F5 (A1A1F5_BIFAA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Methylenetetrahydrofolate reductase RuleBase RU003862
EC=1.5.1.20 RuleBase RU003862

Gene names

Name:	metF EMBL BAF39538.1
Ordered Locus Names:	BAD_0757

Organism

Bifidobacterium adolescentis (strain ATCC 15703 / DSM 20083 / NCTC 11814 / E194a) [Complete proteome] [HAMAP]

Taxonomic identifier

367928 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Bifidobacteriales › Bifidobacteriaceae › Bifidobacterium

Protein attributes

Sequence length	279 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	5-methyltetrahydrofolate + NAD(P)+ = 5,10-methylenetetrahydrofolate + NAD(P)H. RuleBase RU003862
Cofactor	FAD By similarity. RuleBase RU003862
Pathway	One-carbon metabolism; tetrahydrofolate pathway. RuleBase RU004255
Sequence similarities	Belongs to the methylenetetrahydrofolate reductase family. RuleBase RU003862

Ontologies

Keywords
Biological process	Amino-acid biosynthesis RuleBase RU004255
Ligand	FAD RuleBase RU003862 Flavoprotein RuleBase RU003862
Molecular function	Oxidoreductase RuleBase RU003862
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	methionine biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	methylenetetrahydrofolate reductase (NADPH) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A1A1F5 [UniParc]. Last modified January 23, 2007. Version 1. Checksum: 01EACB1B25057079	FASTA	279	30,697
	10 20 30 40 50 60 MHSPIFSLEV FPPKRTSPVG TIYDTLDGLQ GLDPDFISVT YGTGKSSDRT LTARIAHTVN 70 80 90 100 110 120 EYGIPAVAHL TAQYLDKDDV DEALDLFDQA KVSGVLALRG DRVEGAEPAG VFDHASDLAA 130 140 150 160 170 180 YIREKRPDLK IYGACYPEKH PQAATLEEDI DNLKKKVDAG VSHLISQLFY DNEDFLRFVD 190 200 210 220 230 240 KARAAGIDVP IEAGIMPVMN AKSVLRMSKM CESRVPEKLA VLLDKWGSDT ALLKEAGIAY 250 260 270 ASEQICDLAA RGVDGVHLYT MNHPCVSRRI WSNVKPFFV

References

[1]

"Bifidobacterium adolescentis complete genome sequence." Suzuki T., Tsuda Y., Kanou N., Inoue T., Kumazaki K., Nagano S., Hirai S., Tanaka K., Watanabe K. Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 15703 / DSM 20083 / NCTC 11814 / E194a.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP009256 Genomic DNA. Translation: BAF39538.1.
RefSeq	YP_909620.1. NC_008618.1.
3D structure databases
ProteinModelPortal	A1A1F5.
ModBase	Search...
Protein-protein interaction databases
STRING	A1A1F5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4556410.
GenomeReviews	Gene locus BAD_0757 in contig AP009256_GR.
KEGG	bad:BAD_0757.
NMPDR	fig|1680.3.peg.1339.
PATRIC	21100897. VBIBifAdo27973_0823.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0685.
HOGENOM	HBG649727.
OMA	ITQMFFD.
ProtClustDB	CLSK638816.
Family and domain databases
InterPro	IPR003171. Mehydrof_redctse. IPR004620. MTHF_reductase_bac. [Graphical view]
KO	K00297.
Pfam	PF02219. MTHFR. 1 hit. [Graphical view]
TIGRFAMs	TIGR00676. Fadh2. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A1A1F5_BIFAA

Accession

Primary (citable) accession number: A1A1F5

Entry history

Integrated into UniProtKB/TrEMBL:	January 23, 2007
Last sequence update:	January 23, 2007
Last modified:	December 14, 2011
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)