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Reviewed, UniProtKB/Swiss-Prot A1A0H0 (XYLA_BIFAA)

Last modified November 3, 2009. Version 22. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Xylose isomerase
    EC=5.3.1.5
Gene names
Name: xylA
Ordered Locus Names: BAD_0422
OrganismBifidobacterium adolescentis (strain ATCC 15703 / DSM 20083) [Complete proteome] [HAMAP]
Taxonomic identifier367928 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Bifidobacteriales › Bifidobacteriaceae › Bifidobacterium

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Protein attributes

Sequence length449 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

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General annotation (Comments)

Catalytic activity

D-xylose = D-xylulose. HAMAP MF_00455

Cofactor

Binds 2 magnesium ions per subunit By similarity.

Subunit structure

Homotetramer By similarity.

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the xylose isomerase family.

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Ontologies

Keywords
   Biological processCarbohydrate metabolism
Pentose shunt
Xylose metabolism
   Cellular componentCytoplasm
   LigandMagnesium
Metal-binding
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processD-xylose metabolic process

Inferred from electronic annotation. Source: HAMAP

pentose-phosphate shunt

Inferred from electronic annotation. Source: HAMAP

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionmagnesium ion binding

Inferred from electronic annotation. Source: HAMAP

xylose isomerase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 449449Xylose isomerase HAMAP MF_00455
PRO_1000026431

Sites

Active site1021 By similarity
Active site1051 By similarity
Metal binding2331Magnesium 1 By similarity
Metal binding2691Magnesium 1 By similarity
Metal binding2691Magnesium 2 By similarity
Metal binding2721Magnesium 2 By similarity
Metal binding2971Magnesium 1 By similarity
Metal binding3081Magnesium 2 By similarity
Metal binding3101Magnesium 2 By similarity
Metal binding3411Magnesium 1 By similarity

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Sequences

Sequence LengthMass (Da)Tools
A1A0H0-1 [UniParc].

Last modified January 23, 2007. Version 1.
Checksum: 1A8C71CEFF37922C

FASTA44950,765
        10         20         30         40         50         60 
MGLWDIDKIP YVGREKGPQE GLAFHYYDAD KVVAGKKMKD WLRFGVAWWH TFDQQLVDPF 

        70         80         90        100        110        120 
GTGTAQRPWY GKYSDPEDEA LAKVDYAFEF FQKLGVEYFC FHDRDIAPEG DTLRETDKNL 

       130        140        150        160        170        180 
DKVVDKIEEN MKSTGIKLLW NTSSLFTNPR FVSGASTSPF ADIYAYAGGQ LKHSLEIAKR 

       190        200        210        220        230        240 
LGAENYVFWG GREGYENLWN TQMKREQEHM AKFFHMCHDY AKEIGLDAQF LIEPKAKEPT 

       250        260        270        280        290        300 
MFQYDFDAAT AINFLRTYDL MDVFKLNLEG NHANLAGHTY QHEIRTAREA GVLGSLDANQ 

       310        320        330        340        350        360 
GDKLIGWDMD EFPTDLYETS TVMWEVLAEG QIGPHGGLNF DAKPRRTSFT AEDLFRSHIA 

       370        380        390        400        410        420 
GMDSFAAGLL VAAKMHEDKV IENLQAERYS SFDSGIGATV ENGTASLASL EEYALDIPQS 

       430        440 
KLIEATKSDH LESVKATINN YMIDALAEA

« Hide

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References

[1]"Bifidobacterium adolescentis complete genome sequence."
Suzuki T., Tsuda Y., Kanou N., Inoue T., Kumazaki K., Nagano S., Hirai S., Tanaka K., Watanabe K.
Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

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Cross-references

Sequence databases

AP009256 Genomic DNA. Translation: BAF39203.1.
RefSeqYP_909285.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGA1A0H0.

Genome annotation databases

GeneID4556760.
GenomeReviewsGene locus BAD_0422 in contig AP009256_GR.
KEGGbad:BAD_0422.
NMPDRfig|1680.3.peg.679.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMAQFLIEPK.

Family and domain databases

HAMAPMF_00455.
[Tree]
InterProIPR013022. Xyl_isomerase-like_TIM-brl.
IPR012307. Xyl_isomerase_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
IPR018115. Xylose_isomerase_AS.
[Graphical view]
Gene3DG3DSA:3.20.20.150. Xyl_isomerase-like_TIM-brl. 1 hit.
PfamPF01261. AP_endonuc_2. 1 hit.
[Graphical view]
PRINTSPR00688. XYLOSISMRASE.
TIGRFAMsTIGR02630. xylose_isom_A. 1 hit.
PROSITEPS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view]
ProtoNetSearch...

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Entry information

Entry nameXYLA_BIFAA
AccessionPrimary (citable) accession number: A1A0H0
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: January 23, 2007
Last modified: November 3, 2009
This is version 22 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

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Relevant documents

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents