ID   A0ZZD7_BIFAA            Unreviewed;       314 AA.
AC   A0ZZD7;
DT   23-JAN-2007, integrated into UniProtKB/TrEMBL.
DT   23-JAN-2007, sequence version 1.
DT   27-MAR-2024, entry version 82.
DE   SubName: Full=Probable serine-threonine protein kinase {ECO:0000313|EMBL:BAF38820.1};
GN   Name=pknA {ECO:0000313|EMBL:BAF38820.1};
GN   OrderedLocusNames=BAD_0039 {ECO:0000313|EMBL:BAF38820.1};
OS   Bifidobacterium adolescentis (strain ATCC 15703 / DSM 20083 / NCTC 11814 /
OS   E194a).
OC   Bacteria; Actinomycetota; Actinomycetes; Bifidobacteriales;
OC   Bifidobacteriaceae; Bifidobacterium.
OX   NCBI_TaxID=367928 {ECO:0000313|EMBL:BAF38820.1, ECO:0000313|Proteomes:UP000008702};
RN   [1] {ECO:0000313|EMBL:BAF38820.1, ECO:0000313|Proteomes:UP000008702}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 15703 / DSM 20083 / NCTC 11814 / E194a
RC   {ECO:0000313|Proteomes:UP000008702};
RA   Suzuki T., Tsuda Y., Kanou N., Inoue T., Kumazaki K., Nagano S., Hirai S.,
RA   Tanaka K., Watanabe K.;
RT   "Bifidobacterium adolescentis complete genome sequence.";
RL   Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-
CC         [protein]; Xref=Rhea:RHEA:17989, Rhea:RHEA-COMP:9863, Rhea:RHEA-
CC         COMP:11604, ChEBI:CHEBI:15378, ChEBI:CHEBI:29999, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:83421, ChEBI:CHEBI:456216; EC=2.7.11.1;
CC         Evidence={ECO:0000256|ARBA:ARBA00001433};
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-
CC         threonyl-[protein]; Xref=Rhea:RHEA:46608, Rhea:RHEA-COMP:11060,
CC         Rhea:RHEA-COMP:11605, ChEBI:CHEBI:15378, ChEBI:CHEBI:30013,
CC         ChEBI:CHEBI:30616, ChEBI:CHEBI:61977, ChEBI:CHEBI:456216;
CC         EC=2.7.11.1; Evidence={ECO:0000256|ARBA:ARBA00000775};
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DR   EMBL; AP009256; BAF38820.1; -; Genomic_DNA.
DR   RefSeq; WP_003807258.1; NC_008618.1.
DR   AlphaFoldDB; A0ZZD7; -.
DR   SMR; A0ZZD7; -.
DR   STRING; 367928.BAD_0039; -.
DR   PaxDb; 1680-BADO_0029; -.
DR   GeneID; 56674084; -.
DR   KEGG; bad:BAD_0039; -.
DR   HOGENOM; CLU_000288_63_44_11; -.
DR   Proteomes; UP000008702; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   CDD; cd14014; STKc_PknB_like; 1.
DR   Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   InterPro; IPR000719; Prot_kinase_dom.
DR   InterPro; IPR008271; Ser/Thr_kinase_AS.
DR   PANTHER; PTHR45832:SF24; PROTEIN KINASE DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR45832; SERINE/THREONINE-PROTEIN KINASE SAMKA-RELATED-RELATED; 1.
DR   Pfam; PF00069; Pkinase; 1.
DR   SMART; SM00220; S_TKc; 1.
DR   SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR   PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR   PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE   4: Predicted;
KW   Kinase {ECO:0000313|EMBL:BAF38820.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008702};
KW   Transferase {ECO:0000313|EMBL:BAF38820.1}.
FT   DOMAIN          13..276
FT                   /note="Protein kinase"
FT                   /evidence="ECO:0000259|PROSITE:PS50011"
SQ   SEQUENCE   314 AA;  34622 MW;  7BDAA7168A3AA2E8 CRC64;
     MKLVEGQLIH RRYRLDSRLA QGGMGEVWKG YDIQLGRPVA IKALRGDLGV TQEAKLLRLR
     AEAHNSANLA HPNIAALFEY YEHDGIGFLI MEYVPSKSLA DLYHEQNGPM DPIKLLPILI
     QTARGLFVAH SHGVIHRDVK PANIMVSDSG EVKITDFGVS YSTNQEQITQ DGMVVGTAQY
     ISPEQAQGKH ATPQSDIYSL GVVAYEGLCG HRPFTGATPV DIAAAHVNNP VPPLPDTVDV
     QLREFVMSML AKDPLDRPKD ALVVSRTLSR IERRLLDQQT QLADTMVVSS GGRLPRRVVS
     KPHISVSNDW KEQG
//