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Protein

Cell cycle control protein 50C

Gene

TMEM30CP

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Caution

According to PubMed:17258408, the major transcript has no stop-codon and is probably non protein-coding. A minor transcript is also expressed and encodes the displayed protein which misses C-terminal part compared to other mammalian orthologs.Curated

Names & Taxonomyi

Protein namesi
Recommended name:
Cell cycle control protein 50C
Alternative name(s):
Transmembrane protein 30C
Gene namesi
Name:TMEM30CPImported
Synonyms:CDC50C, TMEM30C
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Unplaced

Organism-specific databases

HGNCiHGNC:30443 TMEM30CP
MIMi611030 gene
neXtProtiNX_A0ZSE6

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 34CytoplasmicSequence analysisAdd BLAST34
Transmembranei35 – 55HelicalSequence analysisAdd BLAST21
Topological domaini56 – 113ExtracellularSequence analysisAdd BLAST58

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002928451 – 113Cell cycle control protein 50CAdd BLAST113

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi66N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiA0ZSE6
PRIDEiA0ZSE6

Expressioni

Tissue specificityi

Specifically expressed in testis.1 Publication

Gene expression databases

CleanExiHS_TMEM30C

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000402698

Structurei

3D structure databases

ProteinModelPortaliA0ZSE6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the CDC50/LEM3 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG2952 Eukaryota
COG5035 LUCA
HOGENOMiHOG000207968
InParanoidiA0ZSE6
PhylomeDBiA0ZSE6

Family and domain databases

InterProiView protein in InterPro
IPR005045 CDC50/LEM3_fam
IPR030353 TMEM30C
PANTHERiPTHR10926 PTHR10926, 1 hit
PTHR10926:SF1 PTHR10926:SF1, 1 hit

Sequencei

Sequence statusi: Complete.

A0ZSE6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEERAQHCLS RLLDNSALKQ QELPIHRLYF TARRVLFVFF ATGIFCLCMG
60 70 80 90 100
IILILSARST QEIEINYTRI CANCAKLREN ASNFDKECTC SIPFYLSGKM
110
MVGEIQETRL TLH
Length:113
Mass (Da):13,039
Last modified:June 26, 2007 - v2
Checksum:iE2526360CFFDF5E1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC129803 Genomic DNA No translation available.
AB250297 mRNA Translation: BAF41210.1
UniGeneiHs.652353

Similar proteinsi

Entry informationi

Entry nameiCC50C_HUMAN
AccessioniPrimary (citable) accession number: A0ZSE6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 26, 2007
Last sequence update: June 26, 2007
Last modified: May 23, 2018
This is version 69 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 3
    Human chromosome 3: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. SIMILARITY comments
    Index of protein domains and families

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