CCK1R

Functionⁱ

GO - Molecular functionⁱ

cholecystokinin receptor activity Source: GO_Central
peptide binding Source: GO_Central

Complete GO annotation...

GO - Biological processⁱ

cellular response to hormone stimulus Source: GO_Central
cholecystokinin signaling pathway Source: GO_Central
digestion Source: GO_Central
feeding behavior Source: GO_Central
regulation of hormone secretion Source: GO_Central
response to peptide Source: GO_Central

Complete GO annotation...

Keywordsⁱ

Molecular function	G-protein coupled receptorUniRule annotation, Receptor, Transducer

Molecular function

G-protein coupled receptorUniRule annotation, Receptor, Transducer

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: Cholecystokinin type 1 receptorImported
Gene namesⁱ	Name:CCK1RImported
Organismⁱ	Gallus gallus (Chicken)Imported
Taxonomic identifierⁱ	9031 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Sauropsida › Sauria › Archelosauria › Archosauria › Dinosauria › Saurischia › Theropoda › Coelurosauria › Aves › Neognathae › Galloanserae › Galliformes › Phasianidae › Phasianinae › Gallus

Subcellular locationⁱ

Topology

Feature key	Position(s)	DescriptionActions	Length
Transmembraneⁱ	48 – 70	HelicalSequence analysisAdd BLAST	23
Transmembraneⁱ	82 – 102	HelicalSequence analysisAdd BLAST	21
Transmembraneⁱ	122 – 140	HelicalSequence analysisAdd BLAST	19
Transmembraneⁱ	161 – 182	HelicalSequence analysisAdd BLAST	22
Transmembraneⁱ	212 – 235	HelicalSequence analysisAdd BLAST	24
Transmembraneⁱ	312 – 332	HelicalSequence analysisAdd BLAST	21
Transmembraneⁱ	352 – 374	HelicalSequence analysisAdd BLAST	23

GO - Cellular componentⁱ

integral component of plasma membrane Source: GO_Central

Complete GO annotation...

Keywords - Cellular componentⁱ

Membrane

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSGALG00000014363.

Bgeeⁱ

ENSGALG00000014363.

Interactionⁱ

Protein-protein interaction databases

STRINGⁱ	9031.ENSGALP00000023158.

STRINGⁱ

9031.ENSGALP00000023158.

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	A0ZPS0.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	61 – 372	G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST		312

Sequence similaritiesⁱ

Belongs to the G-protein coupled receptor 1 family.UniRule annotation

Keywords - Domainⁱ

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGⁱ	KOG3656. Eukaryota. ENOG410XRW9. LUCA.
HOGENOMⁱ	HOG000294067.
HOVERGENⁱ	HBG036927.
KEGG Orthology (KO) More...KOⁱ	K04194.
OMAⁱ	YSYSHMS.
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G084J.
PhylomeDBⁱ	A0ZPS0.

Family and domain databases

Gene3Dⁱ	4.10.670.10. 1 hit.
InterProⁱ	View protein in InterPro IPR009126. Cholcskin_rcpt. IPR000596. Cholcy_rcpt_A. IPR015276. CholecystokininA_recpt_N. IPR000276. GPCR_Rhodpsn. IPR017452. GPCR_Rhodpsn_7TM.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00001. 7tm_1. 1 hit. PF09193. CholecysA-Rec_N. 1 hit.
PRINTSⁱ	PR01822. CCYSTOKININR. PR00524. CCYSTOKNINAR. PR00237. GPCRRHODOPSN.
SMARTⁱ	View protein in SMART SM01381. 7TM_GPCR_Srsx. 1 hit.
PROSITEⁱ	View protein in PROSITE PS00237. G_PROTEIN_RECEP_F1_1. 1 hit. PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.

Sequenceⁱ

Sequence statusⁱ: Complete.

A0ZPS0-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MEIVDASFLE NSTNITALLC DILLENETFY CVDDPPYSSK DLHQIIRILL 
        60         70         80         90        100
YCLIFLLSVL GNILVITVLI RNKQMRTVTN TFLLSLAVSD LMLCLFCMPF 
       110        120        130        140        150
TLIPNLLKDF IFGSTVCKTA TYFMGISVSV STFNLVAISL ERYSAICKPL 
       160        170        180        190        200
QSRVWQTKSH ALKVIAATWC VSFTIMSPYP IYSKLVPFTK YNNSTANMCR 
       210        220        230        240        250
LLWPSDVIQQ SWYTFLLLIL FLIPGIIMMV AYGLISLELY RGIKFDTSQR 
       260        270        280        290        300
RSSRERKGST SIAKYEDGDG CYLHKAKRKR KVPLQQLSTM SNSKIDRVRS 
       310        320        330        340        350
SSSSANLMAK KLVIRMLMVI VVLFFICWTP IFSVNAWRAF DTASADLHLS 
       360        370        380        390        400
GAPISFIHLL SYTSACVNPI IYCFMNKRFR MGFLATFTCC AKQKPPVIRG 
       410        420 
EVGDEEEGKT TRASLSKCSY THMNMSAPP

Length:429

Mass (Da):48,530

Last modified:January 23, 2007 - v1

Checksum:ⁱ791BF34FBEA11A0B

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AB214534 mRNA. Translation: BAF37117.1.
NCBI Reference Sequences More...RefSeqⁱ	NP_001074970.1. NM_001081501.1.
UniGeneⁱ	Gga.38921.

Genome annotation databases

GeneIDⁱ	422801.
KEGGⁱ	gga:422801.

Similar proteinsⁱ

Entry	Cluster members	Organisms	Length	Cluster ID	Cluster name	Size
A0ZPS0	A0A1V4JFM6 UPI0007712296 H0ZG11 UPI000194C382 A0A087QNS3 UPI0004F482B4 A0A091IWX8 UPI00051F0EE1 A0A091PVU9 UPI000522A216 +68	Gallus gallus (Chicken) Patagioenas fasciata monilis Parus major (Great tit) Taeniopygia guttata (Zebra finch) (Poephila guttata) Aptenodytes forsteri (Emperor penguin) Egretta garzetta (little egret) Haliaeetus albicilla (White-tailed sea-eagle) Sturnus vulgaris (Starling) Pseudopodoces humilis (Tibetan ground jay) (Podoces humilis) Charadrius vociferus (Killdeer) (Aegialitis vocifera) And more	429	UniRef90_A0ZPS0	Cluster: Cholecystokinin type 1 receptor	79

Entry	Cluster members	Organisms	Length	Cluster ID	Cluster name	Size
A0ZPS0	P30551 V9H0R3 F1LQR7 UPI00081028E3 UPI000A305232 O08786 Q3TPL0 UPI000A3182C2 UPI000A319A2A G5B014 +344	Rattus norvegicus (Rat) Mus pahari (Gairdner's shrew-mouse) (Coelomys pahari) Mus musculus (Mouse) Mus caroli (Ryukyu mouse) (Ricefield mouse) Heterocephalus glaber (Naked mole rat) Chinchilla lanigera (Long-tailed chinchilla) (Chinchilla villidera) Nannospalax galili (Northern Israeli blind subterranean mole rat) (Spalax galili) Castor canadensis (Beaver) Mesocricetus auratus (Golden hamster) Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) And more	444	UniRef50_P30551	Cluster: Cholecystokinin receptor type A	355

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AB214534 mRNA. Translation: BAF37117.1.
NCBI Reference Sequences More...RefSeqⁱ	NP_001074970.1. NM_001081501.1.
UniGeneⁱ	Gga.38921.

3D structure databases

ProteinModelPortalⁱ	A0ZPS0.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	9031.ENSGALP00000023158.

STRINGⁱ

9031.ENSGALP00000023158.

Protein family/group databases

GPCRDBⁱ	Search...

GPCRDBⁱ

Search...

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

GeneIDⁱ	422801.
KEGGⁱ	gga:422801.

Organism-specific databases

CTDⁱ	886.

CTDⁱ

886.

Phylogenomic databases

eggNOGⁱ	KOG3656. Eukaryota. ENOG410XRW9. LUCA.
HOGENOMⁱ	HOG000294067.
HOVERGENⁱ	HBG036927.
KEGG Orthology (KO) More...KOⁱ	K04194.
OMAⁱ	YSYSHMS.
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G084J.
PhylomeDBⁱ	A0ZPS0.

Gene expression databases

Bgeeⁱ	ENSGALG00000014363.

Bgeeⁱ

ENSGALG00000014363.

Family and domain databases

Gene3Dⁱ	4.10.670.10. 1 hit.
InterProⁱ	View protein in InterPro IPR009126. Cholcskin_rcpt. IPR000596. Cholcy_rcpt_A. IPR015276. CholecystokininA_recpt_N. IPR000276. GPCR_Rhodpsn. IPR017452. GPCR_Rhodpsn_7TM.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00001. 7tm_1. 1 hit. PF09193. CholecysA-Rec_N. 1 hit.
PRINTSⁱ	PR01822. CCYSTOKININR. PR00524. CCYSTOKNINAR. PR00237. GPCRRHODOPSN.
SMARTⁱ	View protein in SMART SM01381. 7TM_GPCR_Srsx. 1 hit.
PROSITEⁱ	View protein in PROSITE PS00237. G_PROTEIN_RECEP_F1_1. 1 hit. PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	A0ZPS0_CHICK
Accessionⁱ	A0ZPS0Primary (citable) accession number: A0ZPS0 Secondary accession number(s): F1NIK5
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	January 23, 2007
	Last sequence update:	January 23, 2007
	Last modified:	June 7, 2017
	This is version 81 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - A0ZPS0 (A0ZPS0_CHICK)

Your basket is currently empty.

Cholecystokinin type 1 receptor

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Protein family/group databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Sequenceⁱ

Cross-referencesⁱ

Entry informationⁱ