A0ZEE0 (A0ZEE0_NODSP) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Peptide methionine sulfoxide reductase MsrA HAMAP-Rule MF_01401
Short name=Protein-methionine-S-oxide reductase HAMAP-Rule MF_01401
EC=1.8.4.11 HAMAP-Rule MF_01401

Alternative name(s):
Peptide-methionine (S)-S-oxide reductase HAMAP-Rule MF_01401

Gene names

Name:	msrA HAMAP-Rule MF_01401
ORF Names:	N9414_12653 EMBL EAW45703.1

Organism

Nodularia spumigena CCY9414 EMBL EAW45703.1

Taxonomic identifier

313624 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Cyanobacteria › Nostocales › Nostocaceae › Nodularia › Nodularia spumigena

Protein attributes

Sequence length	222 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine By similarity. HAMAP-Rule MF_01401
Catalytic activity	L-methionine + thioredoxin disulfide + H2O = L-methionine (S)-S-oxide + thioredoxin. HAMAP-Rule MF_01401 SAAS SAAS002569 Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (S)-S-oxide + thioredoxin. HAMAP-Rule MF_01401 SAAS SAAS002569
Sequence similarities	Belongs to the MsrA Met sulfoxide reductase family. HAMAP-Rule MF_01401

Ontologies

Keywords
Molecular function	Oxidoreductase HAMAP-Rule MF_01401 SAAS SAAS002569 EMBL EAW45703.1
Gene Ontology (GO)
Biological_process	cellular protein modification process Inferred from electronic annotation. Source: HAMAP
Molecular_function	peptide-methionine (S)-S-oxide reductase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	56	1	By similarity HAMAP-Rule MF_01401

Sequences

	Sequence		Length	Mass (Da)
	A0ZEE0 [UniParc]. Last modified January 23, 2007. Version 1. Checksum: C85D19D8940EB27C	FASTA	222	24,178
	10 20 30 40 50 60 MGLFGFGKKL AIPTPEEALP GRAKSMPVPN EHYVNKNTLT APFPEGLEKA IFGLGCFWGA 70 80 90 100 110 120 ERKFWQLPGV YTTAVGYAAG STPNPSYDEV CSGMTGHNEV VLVVFDPNVV SFSQLLKVFW 130 140 150 160 170 180 ESHNPTQGMR QGNDAGTQYR SGIYVYSPQQ KQLAEASRDA YQEALNKAGY GKITTEILDA 190 200 210 220 PEFYYAEAYH QQYLAKNPNG YCGLGGTKVA CPIGVVESQI SG

References

[1]	Stal L., Ferriera S., Johnson J., Kravitz S., Halpern A., Remington K., Beeson K., Tran B., Rogers Y.-H., Friedman R., Venter J.C. Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: CCY9414 EMBL EAW45703.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AAVW01000022 Genomic DNA. Translation: EAW45703.1.
3D structure databases
ProteinModelPortal	A0ZEE0.
SMR	A0ZEE0. Positions 12-212.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EAW45703; EAW45703; N9414_12653.
PATRIC	25517126. VBINodSpu128623_1786.
Family and domain databases
Gene3D	3.30.1060.10. 1 hit.
HAMAP	MF_01401. MsrA.
InterPro	IPR002569. Met_Sox_Rdtase_MsrA. [Graphical view]
Pfam	PF01625. PMSR. 1 hit. [Graphical view]
SUPFAM	SSF55068. MsrA. 1 hit.
TIGRFAMs	TIGR00401. msrA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A0ZEE0_NODSP

Accession

Primary (citable) accession number: A0ZEE0

Entry history

Integrated into UniProtKB/TrEMBL:	January 23, 2007
Last sequence update:	January 23, 2007
Last modified:	April 3, 2013
This is version 38 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)