ID   A0Z9S0_NODSP            Unreviewed;      2595 AA.
AC   A0Z9S0;
DT   23-JAN-2007, integrated into UniProtKB/TrEMBL.
DT   23-JAN-2007, sequence version 1.
DT   24-JAN-2024, entry version 91.
DE   SubName: Full=Long-chain-fatty-acid--CoA ligase {ECO:0000313|EMBL:AHJ29020.1};
DE            EC=6.2.1.3 {ECO:0000313|EMBL:AHJ29020.1};
GN   ORFNames=NSP_26920 {ECO:0000313|EMBL:AHJ29020.1};
OS   Nodularia spumigena CCY9414.
OC   Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales; Aphanizomenonaceae;
OC   Nodularia.
OX   NCBI_TaxID=313624 {ECO:0000313|EMBL:AHJ29020.1, ECO:0000313|Proteomes:UP000019325};
RN   [1] {ECO:0000313|EMBL:AHJ29020.1, ECO:0000313|Proteomes:UP000019325}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CCY9414 {ECO:0000313|EMBL:AHJ29020.1};
RX   PubMed=23555932;
RA   Voss B., Bolhuis H., Fewer D.P., Kopf M., Moke F., Haas F., El-Shehawy R.,
RA   Hayes P., Bergman B., Sivonen K., Dittmann E., Scanlan D.J., Hagemann M.,
RA   Stal L.J., Hess W.R.;
RT   "Insights into the physiology and ecology of the brackish-water-adapted
RT   Cyanobacterium Nodularia spumigena CCY9414 based on a genome-transcriptome
RT   analysis.";
RL   PLoS ONE 8:E60224-E60224(2013).
CC   -!- COFACTOR:
CC       Name=pantetheine 4'-phosphate; Xref=ChEBI:CHEBI:47942;
CC         Evidence={ECO:0000256|ARBA:ARBA00001957};
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DR   EMBL; CP007203; AHJ29020.1; -; Genomic_DNA.
DR   STRING; 313624.NSP_26920; -.
DR   PATRIC; fig|313624.11.peg.2712; -.
DR   eggNOG; COG1020; Bacteria.
DR   HOGENOM; CLU_000022_44_1_3; -.
DR   Proteomes; UP000019325; Chromosome.
DR   GO; GO:0004467; F:long-chain fatty acid-CoA ligase activity; IEA:UniProtKB-EC.
DR   GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR   CDD; cd12117; A_NRPS_Srf_like; 1.
DR   CDD; cd12116; A_NRPS_Ta1_like; 1.
DR   CDD; cd19543; DCL_NRPS; 1.
DR   CDD; cd19534; E_NRPS; 1.
DR   CDD; cd19531; LCL_NRPS-like; 1.
DR   Gene3D; 3.30.300.30; -; 2.
DR   Gene3D; 3.40.50.980; -; 4.
DR   Gene3D; 1.10.1200.10; ACP-like; 2.
DR   Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 3.
DR   Gene3D; 3.30.559.30; Nonribosomal peptide synthetase, condensation domain; 3.
DR   InterPro; IPR010071; AA_adenyl_domain.
DR   InterPro; IPR036736; ACP-like_sf.
DR   InterPro; IPR025110; AMP-bd_C.
DR   InterPro; IPR045851; AMP-bd_C_sf.
DR   InterPro; IPR020845; AMP-binding_CS.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR   InterPro; IPR023213; CAT-like_dom_sf.
DR   InterPro; IPR001242; Condensatn.
DR   InterPro; IPR010060; NRPS_synth.
DR   InterPro; IPR020806; PKS_PP-bd.
DR   InterPro; IPR009081; PP-bd_ACP.
DR   InterPro; IPR006162; Ppantetheine_attach_site.
DR   NCBIfam; TIGR01733; AA-adenyl-dom; 2.
DR   NCBIfam; TIGR01720; NRPS-para261; 1.
DR   PANTHER; PTHR45527:SF1; FATTY ACID SYNTHASE; 1.
DR   PANTHER; PTHR45527; NONRIBOSOMAL PEPTIDE SYNTHETASE; 1.
DR   Pfam; PF00501; AMP-binding; 2.
DR   Pfam; PF13193; AMP-binding_C; 2.
DR   Pfam; PF00668; Condensation; 3.
DR   Pfam; PF00550; PP-binding; 2.
DR   SMART; SM00823; PKS_PP; 2.
DR   SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 2.
DR   SUPFAM; SSF47336; ACP-like; 2.
DR   SUPFAM; SSF52777; CoA-dependent acyltransferases; 6.
DR   PROSITE; PS00455; AMP_BINDING; 2.
DR   PROSITE; PS50075; CARRIER; 2.
DR   PROSITE; PS00012; PHOSPHOPANTETHEINE; 2.
PE   4: Predicted;
KW   Ligase {ECO:0000313|EMBL:AHJ29020.1};
KW   Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553}.
FT   DOMAIN          961..1036
FT                   /note="Carrier"
FT                   /evidence="ECO:0000259|PROSITE:PS50075"
FT   DOMAIN          2031..2105
FT                   /note="Carrier"
FT                   /evidence="ECO:0000259|PROSITE:PS50075"
SQ   SEQUENCE   2595 AA;  292352 MW;  CDFC0BADABF22AF4 CRC64;
     MKVESSIIDI YELSPMQAGM LFHTLYAPNS GVYFEQRSCL IRGDLNLAAF RQAWQGVVKR
     HSVLRTAFHY SELEKPLQVV YDSVDLPWQK LDWCGLKVTE KEAKLTEFLE SDCNCGFDLQ
     QPPLMRCAVI RLEANKYQFI WSHHHLLMDG WCNGILLTEV FTLYKAFCQE QDLILPPPTP
     YSNYILWLQQ QNPEQAENYW RKHLQDFTAP TVLGNRENNQ SSILSQKLKV NSQQTETLQN
     FVRQHRLTLN TLVQGAWALL LSRYSDENDV IFGTTVSGRP PELPQVAKIV GLFINTLPVR
     VDVDGERQII PWLQQLQGEQ VEREQYSYSS LVDIQGWSSV PRGTPLFESL LVFENYPVSI
     ESIIKTFDQT LQIEDTQGFE KTNYPLTLTV IPGQELLFKV SYDVSCFDAA MISRLLGHLE
     ILLMSMVNDP EQRVAQISIL TTQERQLILK KWNQTTQAYP NQCIHQLFEA QVERTPDEIA
     LVFGEECWTY RELNHKANQL AHYLQQLGVK PETIVGICLE RSPEMIISLL GVLKAGGVYL
     PLDPTYPDER LRWILADAQV EVMLTQRRKD AKEEGRVVCW DADGEAIALQ SIENPISDVT
     AASLAYVIYT SGSTGKPKGV MIEQRSLTNT ITALQQQLGI SCTDHWLAIT TIAFDIAALE
     LFLPLIVGAR VILTPQTALV DPLQIAAIIE QQQITVMQAT PATWRLLIAH GWTGKADLKI
     LCGGETLDQS LAQQLLLSGQ EVWNLYGPTE TTIWSAAQKL THNQPVTIGH PIANTQFYIL
     DQHLQPVPIG VPGELYIAGA GVARGYLNRP ELTTEKFLLK TPLCASAPLR ENTLYKTGDR
     TRYLPDGTIE YLGRIDNQVK IRGFRIELGE IESLLSQHPE VQTSVVVVTE DTSEDKRLVA
     YIVSENPEIT DLRQYLAKHL PDYMIPSQFI TLDALPLTPN GKVDRRTLPK PQFKTSSETI
     APRTPTEELL LSIWQSILNL TSVGITDNFF TLGGHSLLVI RLVSQIQQVF GVDISLRQIF
     ENPTIVELAT LINSSRFVEF NYPTLTLPLE RGGNMISSLP LERGGNMISS LPPLQGGTKG
     GKSLLSFAQQ RLWMLAQIEP ENPSYNVATA LRLTGDVNVD VLTESFKEII QRHEVLRTNF
     LNVDGQGVAV IKPEIDINIP IVDLSFLPLS QQQKLAKEES QQTFNLAESL LLRAKLLYLN
     NHEYILLLTM HHIITDGWSI NVFAQEMATI YQAFSQGKLS PLQPLKIQYA DFAAWQRSQN
     DKFNYQLEYW RQQLESAPEL LELPTDYPRP AIQTFRGQRH SFIISGELTE KIKQLGQETH
     TTLFMVMFSA LSILLHRYSQ QEKIVIGSPV ANRHYPGTDE LIGFFVNTFA LLISLEDNPT
     VAELLPRVRE MVLSAYSHQD VPFEQVVEGL NVARSLSHSP LFQVMLVAEN APTQSIEIPG
     LCWSPLEIDG GTAKFDLTLM IAETDAGLQG KWEYNCDLFT ETTIHRFTEH FQNILLGMTS
     QPSPKISDLS LMSAGELQQI ISFGTSPINL ITDCIQELFE QQVAKFGDEI AVICNHQKIT
     YSELNAKANQ LAYHLKYLGV QPEIAVGICV YRSLYFIIAI LAILKAGGFY VPLDPTYPQE
     RLEFLIEDAQ IQVLLTQQQH IPQLPDLSIF CFDTDTANLG HYPTTNPVNQ STPENLAYVM
     YTSGSTGVPK GVCIPHRGVV RLVKDCNYID LSADESLLQA APIAFDASTF EIWGALLNGS
     RLVILSSQQP TLAEIAQAIT DYQITTLWLT AGLFHLMVDE HIESLKSVKQ LIAGGDVLSA
     VHINKLLQTH PECRVINGYG PTENTTFTCC HSVTDICQGN TVPIGRPINN TQVYILDKHL
     NPLPVGVPGE LYIAGDGLAR GYLNQPDLTA EKFIQHPFPT PHSPLPTPLY KTGDRTRYLP
     HGTIEYLGRL DNQVKIRGFR IELGEIEAVL NQHPAVKECV VITREKQLIA YFIPLDSTPD
     NLRDFLQERL PDYLIPHFFV SLESLPLTTN GKVDRQKLPA IEITSFPDGS IARTDIEAKL
     AEVWSSVLNL SQVGIYDNFF ALGGDSIVVI QLISRANQVG LKLSHKQIFQ HQTIAELAAV
     VISNESILPP QGMITGAVLM TPIQYWFFEQ ELVNQHHFNQ AVFLECSEKL QQQVLVDTIK
     YLLLHHDMLR CQFVSGDLFT QRRRGAERDI GGEIVELEDF PLVFCDLSGF NESEQNRVIQ
     DVAGEIQASL NIGDAPLLRV VHFDLGEVSK LLIVAHHLVV DGVSWRILLA DFQTVYQQVL
     VGKRIVLPAK TISFLSWSEK LHDYAQTEYL KEELTYWLSR NYTEVKLLPI DYSDGSNQVA
     DVETVTIKLS VEDTQGLLTE VPPVYNTQVN DVLLTAVTST ISNWINNPLV LVDLEGYGRN
     FPGEDIDISR TVGWFTAIYP CLLQKSSDDW GEMLKGIKEQ LRTVPNQGFN YGILRYLHNG
     EISEKLQNLP QAEISFNYLG QLDLGLDNGK FQWLPLPEIT TQDKQQTRRY AIEIIGFIRE
     GKLQFDWVYS RQQYQQKTIA QLANNFQQGL KEIINHCRLP NIGGYTPSDF ELGNLNQDTL
     DLVMGMISFE AEGVE
//