Skip Header

Contribute Send feedback
Read comments (?) or add your own

A0RXF7 (A0RXF7_CENSY) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 33. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Delta-aminolevulinic acid dehydratase RuleBase RU000515
EC=4.2.1.24 RuleBase RU000515
Gene names
Ordered Locus Names:CENSYa_1402
OrganismCenarchaeum symbiosum (strain A)
Taxonomic identifier414004 [NCBI]
Taxonomic lineageArchaea › Thaumarchaeota › Cenarchaeales › Cenarchaeaceae › Cenarchaeum

Protein attributes

Sequence length329 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

2 5-aminolevulinate = porphobilinogen + 2 H2O. RuleBase RU000515

Subunit structure

Homooctamer By similarity. PIRSR PIRSR001415-3 RuleBase RU000515

Sequence similarities

Belongs to the ALADH family. RuleBase RU004161

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site1941Schiff-base intermediate with substrate By similarity PIRSR PIRSR001415-1
Active site2471Schiff-base intermediate with substrate By similarity PIRSR PIRSR001415-1
Metal binding1191Zinc; catalytic By similarity PIRSR PIRSR001415-3
Metal binding1211Zinc; catalytic By similarity PIRSR PIRSR001415-3
Metal binding1291Zinc; catalytic By similarity PIRSR PIRSR001415-3
Metal binding2321Magnesium By similarity PIRSR PIRSR001415-5
Binding site2041Substrate 1 By similarity PIRSR PIRSR001415-2
Binding site2161Substrate 1 By similarity PIRSR PIRSR001415-2
Binding site2731Substrate 2 By similarity PIRSR PIRSR001415-2
Binding site3121Substrate 2 By similarity PIRSR PIRSR001415-2

Sequences

Sequence LengthMass (Da)Tools
A0RXF7 [UniParc].

Last modified January 9, 2007. Version 1.
Checksum: D0B78ABD5285BD90

FASTA32935,332
        10         20         30         40         50         60 
MTFPAVRLRR LRRSEGMRAL VRETSVSVDD LICPVFVQES GEQSSVGSMP GMERLPLSGL 

        70         80         90        100        110        120 
AAEIERISAL GIRAVMLFGI PENKDDEGSA ASQRDGIVQK AIPAVRDACK DMVIMADACL 

       130        140        150        160        170        180 
CHYTTSGHCG LVRDGIVDND SSLAALSRIA VSLAGAGADV ISPSAMMDGQ VAAIRSALDS 

       190        200        210        220        230        240 
AGHSGVSTMP HSAKHSSAFY APFRDAADCA PKFGDRRTYQ TPYTGSREPI REVAADIEEG 

       250        260        270        280        290        300 
ADIVMIKPAL AYLDLIAETR RRFDVPVAAY SVSGEYALVK AASMQGWMRE EDMVREILHS 

       310        320 
IKRAGADMIV TYFAKLAAGM IQNEGRRSI

« Hide

References

[1]"Genomic analysis of the uncultivated marine crenarchaeote Cenarchaeum symbiosum."
Hallam S.J., Konstantinidis K.T., Putnam N., Schleper C., Watanabe Y., Sugahara J., Preston C., de la Torre J., Richardson P.M., DeLong E.F.
Proc. Natl. Acad. Sci. U.S.A. 103:18296-18301(2006) [PubMed: 17114289] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: A.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		DP000238 Genomic DNA. Translation: ABK78024.1.

3D structure databases

ProteinModelPortalA0RXF7.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Phylogenomic databases

HOGENOMHBG285270.
OMAADLCFCE.

Family and domain databases

InterProIPR013785. Aldolase_TIM.
IPR001731. Porphobilinogen_synth.
[Graphical view]
Gene3DG3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
PANTHERPTHR11458. AlaD_dehydratase. 1 hit.
PfamPF00490. ALAD. 1 hit.
[Graphical view]
PIRSFPIRSF001415. Porphbilin_synth. 1 hit.
PRINTSPR00144. DALDHYDRTASE.
SMARTSM01004. ALAD. 1 hit.
[Graphical view]
PROSITEPS00169. D_ALA_DEHYDRATASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA0RXF7_CENSY
AccessionPrimary (citable) accession number: A0RXF7
Entry history
Integrated into UniProtKB/TrEMBL: January 9, 2007
Last sequence update: January 9, 2007
Last modified: January 25, 2012
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info