SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

A0RXB3

- GSA1_CENSY

UniProt

A0RXB3 - GSA1_CENSY

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Glutamate-1-semialdehyde 2,1-aminomutase 1

Gene
hemL1, CENSYa_1357
Organism
Cenarchaeum symbiosum (strain A)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

(S)-4-amino-5-oxopentanoate = 5-aminolevulinate.UniRule annotation

Cofactori

Pyridoxal phosphate By similarity.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. glutamate-1-semialdehyde 2,1-aminomutase activity Source: UniProtKB-HAMAP
  2. pyridoxal phosphate binding Source: InterPro
  3. transaminase activity Source: InterPro

GO - Biological processi

  1. protoporphyrinogen IX biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Porphyrin biosynthesis

Keywords - Ligandi

Pyridoxal phosphate

Enzyme and pathway databases

UniPathwayiUPA00251; UER00317.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate-1-semialdehyde 2,1-aminomutase 1 (EC:5.4.3.8)
Short name:
GSA 1
Alternative name(s):
Glutamate-1-semialdehyde aminotransferase 1
Short name:
GSA-AT 1
Gene namesi
Name:hemL1
Ordered Locus Names:CENSYa_1357
OrganismiCenarchaeum symbiosum (strain A)
Taxonomic identifieri414004 [NCBI]
Taxonomic lineageiArchaeaThaumarchaeotaCenarchaealesCenarchaeaceaeCenarchaeum
ProteomesiUP000000758: Chromosome

Subcellular locationi

Cytoplasm Reviewed prediction UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 421421Glutamate-1-semialdehyde 2,1-aminomutase 1UniRule annotationPRO_0000382393Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei258 – 2581N6-(pyridoxal phosphate)lysine By similarity

Structurei

3D structure databases

ProteinModelPortaliA0RXB3.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

HOGENOMiHOG000020210.
KOiK01845.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 2 hits.
HAMAPiMF_00375. HemL_aminotrans_3.
InterProiIPR004639. 4pyrrol_synth_GluAld_NH2Trfase.
IPR005814. Aminotrans_3.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PANTHERiPTHR11986. PTHR11986. 1 hit.
PfamiPF00202. Aminotran_3. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.

Sequencei

Sequence statusi: Complete.

A0RXB3-1 [UniParc]FASTAAdd to Basket

« Hide

MGSRGLFERA RKVIPSGVNS PVRYYAPYPF FAASASGGSI RDADGRKYTD    50
LCNGYGALLL GHGRGEVVRA VSAQLRRGTL FCVPTEQEVE LARLISGNYP 100
SMESTRLVNT GGEATMTAIR LARGFTKRDR IIKFDGCYHG AHGSVLVKAG 150
SGSAHLGIST SEGVPRGLAR QTTVIPYNDE AAFEGAAADD VAAVIVEPVM 200
GNMGVIPPKK GFLRLLRKLS SRLGMQLIFD ETITGFRLSA GGAQEAFGVR 250
PDITTLAKAL GGGLPIAAVG GKKNIMERLA PGGSVYEAST FAGNPVSVSA 300
ALASIRTINR IKGRLYPRLE RAAAALASSI ADDAADLGLD RQINRVASIF 350
QVFFTAEPVT DAASAKRADA ARFDKMFRAL LKNGVFVAPS QFEMASLSAA 400
HTVEDLRNVS AAYRTALGAA R 421
Length:421
Mass (Da):44,446
Last modified:September 1, 2009 - v2
Checksum:iBCE8564B16EC352D
GO

Sequence cautioni

The sequence ABK77980.1 differs from that shown. Reason: Erroneous initiation.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DP000238 Genomic DNA. Translation: ABK77980.1. Different initiation.
RefSeqiYP_876284.1. NC_014820.1.

Genome annotation databases

EnsemblBacteriaiABK77980; ABK77980; CENSYa_1357.
GeneIDi6371537.
KEGGicsy:CENSYa_1357.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DP000238 Genomic DNA. Translation: ABK77980.1 . Different initiation.
RefSeqi YP_876284.1. NC_014820.1.

3D structure databases

ProteinModelPortali A0RXB3.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABK77980 ; ABK77980 ; CENSYa_1357 .
GeneIDi 6371537.
KEGGi csy:CENSYa_1357.

Phylogenomic databases

HOGENOMi HOG000020210.
KOi K01845.

Enzyme and pathway databases

UniPathwayi UPA00251 ; UER00317 .

Family and domain databases

Gene3Di 3.40.640.10. 1 hit.
3.90.1150.10. 2 hits.
HAMAPi MF_00375. HemL_aminotrans_3.
InterProi IPR004639. 4pyrrol_synth_GluAld_NH2Trfase.
IPR005814. Aminotrans_3.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view ]
PANTHERi PTHR11986. PTHR11986. 1 hit.
Pfami PF00202. Aminotran_3. 1 hit.
[Graphical view ]
SUPFAMi SSF53383. SSF53383. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: A.

Entry informationi

Entry nameiGSA1_CENSY
AccessioniPrimary (citable) accession number: A0RXB3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 1, 2009
Last sequence update: September 1, 2009
Last modified: February 19, 2014
This is version 43 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi