A0RR66 (DCD_CAMFF) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Deoxycytidine triphosphate deaminase
Short name=dCTP deaminase
EC=3.5.4.13

Gene names

Name:	dcd
Ordered Locus Names:	CFF8240_1566

Organism

Campylobacter fetus subsp. fetus (strain 82-40) [Complete proteome] [HAMAP]

Taxonomic identifier

360106 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › delta/epsilon subdivisions › Epsilonproteobacteria › Campylobacterales › Campylobacteraceae › Campylobacter › Campylobacter fetus › Campylobacter fetus subsp. fetus

Protein attributes

Sequence length	186 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	dCTP + H2O = dUTP + NH3. HAMAP-Rule MF_00146
Pathway	Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 1/2. HAMAP-Rule MF_00146
Sequence similarities	Belongs to the dCTP deaminase family.

Ontologies

Keywords
Biological process	Nucleotide metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	dUMP biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway dUTP biosynthetic process Inferred from electronic annotation. Source: InterPro pyrimidine ribonucleotide biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular_function	dCTP deaminase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 186	186	Deoxycytidine triphosphate deaminase HAMAP-Rule MF_00146		PRO_1000009700

Sequences

	Sequence		Length	Mass (Da)
	A0RR66 [UniParc]. Last modified January 9, 2007. Version 1. Checksum: 59C4218F97A4EFD9	FASTA	186	20,669
	10 20 30 40 50 60 MGLKSDKWIR EQSIENQMIE PFCEENIGKG VVSYGLSSYG YDIRVGCEFK IFTNIGGTVV 70 80 90 100 110 120 DPKNFDEKNV VDFIGDICIV PPNSFALART VEYFKMPHDV LAICLGKSTY ARCGIIVNVT 130 140 150 160 170 180 PFEPGFNGHI TIEISNTTPL PAKIYANEGI AQVLFLQGDE PCETSYADKK GKYQDQEGIT LPRILK

References

[1]	"Sequence of Campylobacter fetus subsp. fetus 82-40." Fouts D.E., Nelson K.E. Submitted (NOV-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 82-40.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000487 Genomic DNA. Translation: ABK82585.1.
RefSeq	YP_892699.1. NC_008599.1.
3D structure databases
ProteinModelPortal	A0RR66.
ModBase	Search...
Protein-protein interaction databases
STRING	360106.CFF8240_1566.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABK82585; ABK82585; CFF8240_1566.
GeneID	4538902.
KEGG	cff:CFF8240_1566.
PATRIC	20037650. VBICamFet25865_1526.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0717.
HOGENOM	HOG000228600.
KO	K01494.
OMA	RSVLTVC.
ProtClustDB	PRK00416.
Enzyme and pathway databases
BioCyc	CFET360106:GHTH-1564-MONOMER.
UniPathway	UPA00610; UER00665.
Family and domain databases
HAMAP	MF_00146. dCTP_deaminase.
InterPro	IPR011962. dCTP_deam. IPR008180. dUTP_pyroPase. [Graphical view]
Pfam	PF00692. dUTPase. 1 hit. [Graphical view]
TIGRFAMs	TIGR02274. dCTP_deam. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DCD_CAMFF

Accession

Primary (citable) accession number: A0RR66

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	January 9, 2007
Last modified:	May 29, 2013
This is version 42 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program