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Protein

Phosphoglycerate kinase

Gene

pgk

Organism
Campylobacter fetus subsp. fetus (strain 82-40)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.UniRule annotation

Pathwayi: glycolysis

This protein is involved in step 2 of the subpathway that synthesizes pyruvate from D-glyceraldehyde 3-phosphate.UniRule annotation
Proteins known to be involved in the 5 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Phosphoglycerate kinase (pgk)
  3. 2,3-bisphosphoglycerate-independent phosphoglycerate mutase (gpmI)
  4. Enolase (eno)
  5. Pyruvate kinase (pyk)
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes pyruvate from D-glyceraldehyde 3-phosphate, the pathway glycolysis and in Carbohydrate degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei39SubstrateUniRule annotation1
Binding sitei121SubstrateUniRule annotation1
Binding sitei154SubstrateUniRule annotation1
Binding sitei207ATPUniRule annotation1
Binding sitei298ATP; via carbonyl oxygenUniRule annotation1
Binding sitei329ATPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi355 – 358ATPUniRule annotation4

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, Transferase
Biological processGlycolysis
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

UniPathwayiUPA00109; UER00185

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycerate kinaseUniRule annotation (EC:2.7.2.3UniRule annotation)
Gene namesi
Name:pgkUniRule annotation
Ordered Locus Names:CFF8240_1428
OrganismiCampylobacter fetus subsp. fetus (strain 82-40)
Taxonomic identifieri360106 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesCampylobacteraceaeCampylobacter
Proteomesi
  • UP000000760 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10002033231 – 401Phosphoglycerate kinaseAdd BLAST401

Proteomic databases

PRIDEiA0RQT4

Interactioni

Subunit structurei

Monomer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliA0RQT4
SMRiA0RQT4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni23 – 25Substrate bindingUniRule annotation3
Regioni62 – 65Substrate bindingUniRule annotation4

Sequence similaritiesi

Belongs to the phosphoglycerate kinase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000227107
KOiK00927
OMAiDMIFDIG
OrthoDBiPOG091H00YN

Family and domain databases

CDDicd00318 Phosphoglycerate_kinase, 1 hit
Gene3Di3.40.50.1260, 2 hits
HAMAPiMF_00145 Phosphoglyc_kinase, 1 hit
InterProiView protein in InterPro
IPR001576 Phosphoglycerate_kinase
IPR015824 Phosphoglycerate_kinase_N
IPR036043 Phosphoglycerate_kinase_sf
PANTHERiPTHR11406 PTHR11406, 1 hit
PfamiView protein in Pfam
PF00162 PGK, 1 hit
PIRSFiPIRSF000724 Pgk, 1 hit
PRINTSiPR00477 PHGLYCKINASE
SUPFAMiSSF53748 SSF53748, 1 hit

Sequencei

Sequence statusi: Complete.

A0RQT4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSEIISIKDI NFKSGSKVFV RCDFNTPMDE FYNITDDRRI RSAIPTIRYI
60 70 80 90 100
LDQGCSVILA SHLGRPKNGY EEKFSLLPVA KRLSRLIDRE IIFANDVVGN
110 120 130 140 150
DAKTKVAALK QGEVLLLENI RFEKGETKDD VALAKELSEY ANYYVNDAFG
160 170 180 190 200
VCHRAHSSVH AITKFYDEEH RAAGFLLIKE IEFARNLIKR PIRPFVAVVG
210 220 230 240 250
GSKVSGKLQA LTNLLPRVDK LIIGGGMAFT FLKAIGENIG NSLLEEDLIE
260 270 280 290 300
EATNILKKGR ELGVKIYLPV DVVAAQTFSA ESAIKYVSTQ EIPTGWMGLD
310 320 330 340 350
IGPASVRLFR EVLSDAQTIW WNGPMGVFEM DKFSKGSIKM SHAIAESFAT
360 370 380 390 400
TVVGGGDTAD VVERAGDADE MTFISTGGGA SLELIEGKEL PGVKVLLKAE

S
Length:401
Mass (Da):44,029
Last modified:January 9, 2007 - v1
Checksum:iE52CA4E45028BF0A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000487 Genomic DNA Translation: ABK82903.1
RefSeqiWP_011732202.1, NC_008599.1

Genome annotation databases

EnsemblBacteriaiABK82903; ABK82903; CFF8240_1428
KEGGicff:CFF8240_1428

Similar proteinsi

Entry informationi

Entry nameiPGK_CAMFF
AccessioniPrimary (citable) accession number: A0RQT4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: January 9, 2007
Last modified: May 23, 2018
This is version 75 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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