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A0RQC5 (AROA_CAMFF) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 46. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
3-phosphoshikimate 1-carboxyvinyltransferase
EC=2.5.1.19
Alternative name(s):
5-enolpyruvylshikimate-3-phosphate synthase
Short name=EPSP synthase
Short name=EPSPS
Gene names
Name:aroA
Ordered Locus Names:CFF8240_1252
OrganismCampylobacter fetus subsp. fetus (strain 82-40) [Complete proteome] [HAMAP]
Taxonomic identifier360106 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Epsilonproteobacteria › Campylobacterales › Campylobacteraceae › Campylobacter

Protein attributes

Sequence length425 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Phosphoenolpyruvate + 3-phosphoshikimate = phosphate + 5-O-(1-carboxyvinyl)-3-phosphoshikimate. HAMAP MF_00210

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 6/7. HAMAP MF_00210

Subunit structure

Monomer By similarity. HAMAP MF_00210

Subcellular location

Cytoplasm By similarity HAMAP MF_00210.

Sequence similarities

Belongs to the EPSP synthase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Cellular componentCytoplasm
   Molecular functionTransferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular function3-phosphoshikimate 1-carboxyvinyltransferase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 4254253-phosphoshikimate 1-carboxyvinyltransferase HAMAP MF_00210
PRO_1000099675

Sequences

Sequence LengthMass (Da)Tools
A0RQC5 [UniParc].

Last modified January 9, 2007. Version 1.
Checksum: BD0D752FEC38C7D8

FASTA42546,159
        10         20         30         40         50         60 
MIVEALNNPF DAEFNKVSSD KSISHRCAIF SLLSDKVSKI SNYLEAEDTM NSLKIIEKLG 

        70         80         90        100        110        120 
AKVEFKNGVY LITPPKKIVS PNAILECGNS GTAMRIFMGL LAGCDGFFVL SGDKYLNERP 

       130        140        150        160        170        180 
MKRVASPLMQ IGAKIDGRDC ANKAPLAIRG GELNYFAYNS SVASAQVKTA LILAGLCSAG 

       190        200        210        220        230        240 
CKFKEPELSR DHSERMLLGM GAQISQSGLE IEVKPLKGAY LKPLILDVPN DPSSCFFYAV 

       250        260        270        280        290        300 
AAAIIPGSKI IIKNILLNKT RIEAYKVLEK MGAKITYTKT SSTYEDIGDI CVQYSELKSV 

       310        320        330        340        350        360 
DVNQNISWLI DEAPALAIAF ACANGVSTLK NAKELRVKEC DRIAITVAAL KKCGIEAVEL 

       370        380        390        400        410        420 
EDGFSIKGGK PNSATIDSHG DHRIAMSFAI LGLKCGMNIE KSEFIATSFP KFSYFLRELG 


ARVED

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References

[1]"Sequence of Campylobacter fetus subsp. fetus 82-40."
Fouts D.E., Nelson K.E.
Submitted (NOV-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 82-40.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000487 Genomic DNA. Translation: ABK82992.1.
RefSeqYP_892408.1. NC_008599.1.

3D structure databases

ProteinModelPortalA0RQC5.
ModBaseSearch...

Protein-protein interaction databases

STRINGA0RQC5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4538627.
GenomeReviewsGene locus CFF8240_1252 in contig CP000487_GR.
KEGGcff:CFF8240_1252.
NMPDRfig|360106.5.peg.1204.
PATRIC20037024. VBICamFet25865_1225.
TIGRCFF8240_1252.

Phylogenomic databases

eggNOGCOG0128.
HOGENOMHBG646626.
OMAVVMVMAT.
ProtClustDBPRK02427.

Enzyme and pathway databases

BioCycCFET360106:CFF8240_1252-MONOMER.

Family and domain databases

HAMAPMF_00210. EPSP_synth.
[Tree]
InterProIPR001986. Enolpyruvate_Tfrase_dom.
IPR006264. EPSP_synthase.
IPR023193. EPSP_synthase_CS.
IPR013792. RNA3'P_cycl/enolpyr_Trfase_a/b.
[Graphical view]
Gene3DG3DSA:3.65.10.10. EPSP_synthase. 2 hits.
KOK00800.
PfamPF00275. EPSP_synthase. 1 hit.
[Graphical view]
PIRSFPIRSF000505. EPSPS. 1 hit.
SUPFAMSSF55205. RNA3'_cycl/enolpyr_transf_A/B. 1 hit.
TIGRFAMsTIGR01356. AroA. 1 hit.
PROSITEPS00104. EPSP_SYNTHASE_1. 1 hit.
PS00885. EPSP_SYNTHASE_2. False negative.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameAROA_CAMFF
AccessionPrimary (citable) accession number: A0RQC5
Entry history
Integrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: January 9, 2007
Last modified: December 14, 2011
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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