Reviewed, UniProtKB/Swiss-Prot A0RP96 (AROB_CAMFF)

Names and origin

Protein names

Recommended name:
    3-dehydroquinate synthase
    EC=4.2.3.4

Gene names

Name:	aroB
Ordered Locus Names:	CFF8240_0854

Organism

Campylobacter fetus subsp. fetus (strain 82-40) [Complete proteome] [HAMAP]

Taxonomic identifier

360106 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Epsilonproteobacteria › Campylobacterales › Campylobacteraceae › Campylobacter

Protein attributes

Sequence length	346 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate = 3-dehydroquinate + phosphate. HAMAP MF_00110
Cofactor	Divalent metal cations By similarity. NAD By similarity.
Pathway	Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 2/7. HAMAP MF_00110
Subunit structure	Monomer By similarity.
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the dehydroquinate synthase family.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis
Cellular component	Cytoplasm
Ligand	NAD
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	aromatic amino acid family biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	3-dehydroquinate synthase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 346	346	3-dehydroquinate synthase HAMAP MF_00110		PRO_1000117477

Sequences

	Sequence		Length	Mass (Da)
	A0RP96-1 [UniParc]. Last modified January 9, 2007. Version 1. Checksum: 5E441739176B5BC6	FASTA	346	38,771
	10 20 30 40 50 60 MKIDINLNDD NKNYSVFIDE LKNLKFKGKV AVITNSKVGG LYLGEILNLI DADEIFSVCI 70 80 90 100 110 120 PDGEQYKNLA MIEYILEQLF VSRLERNSTL IALGGGVISD MTGFAASIYE RGINFINIPT 130 140 150 160 170 180 TLLAQVDASV GGKTGVNNKF GKNLIGTFYQ PKAVYCETKF LNSLPNREFN AGMAEVIKMA 190 200 210 220 230 240 TMFDKDFFKF IQDNSVENSQ ILKQIIAKCV EIKAGVVAKD EKESGIRAVL NYGHTFAHVI 250 260 270 280 290 300 EMQTNYKKFL HGEAVAIGIN MANHLACKLG LLSKKDLDII EQTLIKFGLP TTYRISDEEV 310 320 330 340 FYDSFFLDKK SENKKIKFIL PNGIGSYALR NDIDKNSVLD ILRMFK

References

[1]	"Sequence of Campylobacter fetus subsp. fetus 82-40." Fouts D.E., Nelson K.E. Submitted (NOV-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000487 Genomic DNA. Translation: ABK82554.1.
RefSeq	YP_892029.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A0RP96.
Genome annotation databases
GeneID	4539063.
GenomeReviews	Gene locus CFF8240_0854 in contig CP000487_GR.
KEGG	cff:CFF8240_0854.
NMPDR	fig|360106.5.peg.813.
TIGR	CFF8240_0854.
Phylogenomic databases
OMA	MAANTIS.
Family and domain databases
HAMAP	MF_00110. [Tree]
InterPro	IPR016303. DHQ_synth. IPR002658. DHQ_synth_AroB. IPR016037. DHQ_synth_AroB_sub. [Graphical view]
PANTHER	PTHR21090:SF1. DHQ_synth_AroB. 1 hit.
Pfam	PF01761. DHQ_synthase. 1 hit. [Graphical view]
PIRSF	PIRSF001455. DHQ_synth. 1 hit.
TIGRFAMs	TIGR01357. aroB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

AROB_CAMFF

Accession

Primary (citable) accession number: A0RP96

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	January 9, 2007
Last modified:	November 3, 2009
This is version 25 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)