Reviewed, UniProtKB/Swiss-Prot A0RMP5 (NTPA_CAMFF)

Names and origin

Protein names

Recommended name:
    Nucleoside-triphosphatase
    EC=3.6.1.15
Alternative name(s):
    Nucleoside triphosphate phosphohydrolase
      Short name=NTPase

Gene names

Ordered Locus Names:

CFF8240_0274

Organism

Campylobacter fetus subsp. fetus (strain 82-40) [Complete proteome] [HAMAP]

Taxonomic identifier

360106 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Epsilonproteobacteria › Campylobacterales › Campylobacteraceae › Campylobacter

Protein attributes

Sequence length	204 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions By similarity.
Catalytic activity	NTP + H2O = NDP + phosphate. HAMAP MF_01405
Cofactor	Divalent cations By similarity.
Subunit structure	Homodimer By similarity.
Sequence similarities	Belongs to the HAM1 NTPase family.

Ontologies

Keywords
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	nucleoside-triphosphatase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 204	204	Nucleoside-triphosphatase HAMAP MF_01405		PRO_1000068411

Sequences

	Sequence		Length	Mass (Da)
	A0RMP5-1 [UniParc]. Last modified January 9, 2007. Version 1. Checksum: 2DE5247E4EFC42BC	FASTA	204	22,655
	10 20 30 40 50 60 MKIVLATNNK DKVKEIKAFY DGYEIYALNE ICEPFEIDET GSSFKENALI KATAVYAKLC 70 80 90 100 110 120 ALKLENEFIA LSDDSGISVE ALGFAPGIYS ARYSGKDATD ASNRKKLTCE LHKLRLKKSG 130 140 150 160 170 180 AFYTACIAVA SKFGNFSTHG FMYGTVIDEE RGDNGFGYDF MFMPDGFDGT IGQLDVKTKL 190 200 AISHRSKGLE LAKYILNSLE KYYK

References

[1]	"Sequence of Campylobacter fetus subsp. fetus 82-40." Fouts D.E., Nelson K.E. Submitted (NOV-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000487 Genomic DNA. Translation: ABK83193.1.
RefSeq	YP_891478.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	4538153.
GenomeReviews	Gene locus CFF8240_0274 in contig CP000487_GR.
KEGG	cff:CFF8240_0274.
NMPDR	fig|360106.5.peg.265.
TIGR	CFF8240_0274.
Phylogenomic databases
OMA	A0RMP5. VYTADWA.
Family and domain databases
HAMAP	MF_01405. [Tree]
InterPro	IPR002637. Ham1p-like. [Graphical view]
PANTHER	PTHR11067. Ham1p_like. 1 hit.
Pfam	PF01725. Ham1p_like. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

NTPA_CAMFF

Accession

Primary (citable) accession number: A0RMP5

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 5, 2008
Last sequence update:	January 9, 2007
Last modified:	June 16, 2009
This is version 16 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)