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Protein

Pyrophosphatase PpaX

Gene

ppaX

Organism
Bacillus thuringiensis (strain Al Hakam)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK/P. Might play a role in controlling the intracellular pyrophosphate pool.UniRule annotation

Catalytic activityi

Diphosphate + H2O = 2 phosphate.UniRule annotation

Cofactori

Mg2+UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei9NucleophileUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase
LigandMagnesium

Names & Taxonomyi

Protein namesi
Recommended name:
Pyrophosphatase PpaXUniRule annotation (EC:3.6.1.1UniRule annotation)
Gene namesi
Name:ppaXUniRule annotation
Ordered Locus Names:BALH_4653
OrganismiBacillus thuringiensis (strain Al Hakam)
Taxonomic identifieri412694 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group
Proteomesi
  • UP000000761 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000671871 – 216Pyrophosphatase PpaXAdd BLAST216

Structurei

3D structure databases

ProteinModelPortaliA0RKU8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the HAD-like hydrolase superfamily. PpaX family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000248344
KOiK06019
OMAiLLIFDWD

Family and domain databases

Gene3Di1.10.150.240, 1 hit
3.40.50.1000, 2 hits
HAMAPiMF_01250 Pyrophosphat_PpaX, 1 hit
InterProiView protein in InterPro
IPR036412 HAD-like_sf
IPR006439 HAD-SF_hydro_IA
IPR006549 HAD-SF_hydro_IIIA
IPR023214 HAD_sf
IPR023198 PGP-like_dom2
IPR023733 Pyrophosphatase_Ppax
PRINTSiPR00413 HADHALOGNASE
SUPFAMiSSF56784 SSF56784, 1 hit
TIGRFAMsiTIGR01549 HAD-SF-IA-v1, 1 hit
TIGR01509 HAD-SF-IA-v3, 1 hit
TIGR01662 HAD-SF-IIIA, 1 hit

Sequencei

Sequence statusi: Complete.

A0RKU8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKINTVLFDL DGTLINTNEL IISSFLHTLH TYYPNQYKRE DVLPFIGPSL
60 70 80 90 100
HDTFSKIDES KVEELITSYR QFNHDHHDEL VEEYETVYET VQELKKQGYK
110 120 130 140 150
VGIVTTKARQ TVEMGLKLSK LDEFFDVVVT IDDVEHVKPH PEPLQKALQL
160 170 180 190 200
LDAKPEEALM VGDNHHDIVG GQNAGTKTAA VSWTLKGRAY LEAYKPDFML
210
DKMSDLLPIL SDMNRS
Length:216
Mass (Da):24,721
Last modified:January 9, 2007 - v1
Checksum:iEEC91212D010A382
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000485 Genomic DNA Translation: ABK87841.1
RefSeqiWP_000700956.1, NC_008600.1

Genome annotation databases

EnsemblBacteriaiABK87841; ABK87841; BALH_4653
KEGGibtl:BALH_4653

Similar proteinsi

Entry informationi

Entry nameiPPAX_BACAH
AccessioniPrimary (citable) accession number: A0RKU8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: January 9, 2007
Last modified: March 28, 2018
This is version 67 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health