A0RJK0 (A0RJK0_BACAH) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Malate dehydrogenase EMBL ABK87393.1
EC=1.1.1.37 EMBL ABK87393.1

Gene names

Name:	mdh EMBL ABK87393.1
Ordered Locus Names:	BALH_4186 EMBL ABK87393.1

Organism

Bacillus thuringiensis (strain Al Hakam) [Complete proteome] [HAMAP] EMBL ABK87393.1

Taxonomic identifier

412694 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Bacilli › Bacillales › Bacillaceae › Bacillus › Bacillus cereus group › Bacillus thuringiensis

Protein attributes

Sequence length	434 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Cofactor	Divalent metal cations. Prefers magnesium or manganese By similarity. PIRSR PIRSR000106-3
Sequence similarities	Belongs to the malic enzymes family. RuleBase RU003427

Ontologies

Keywords
Ligand	Metal-binding RuleBase RU003427 PIRSR PIRSR000106-3
Molecular function	Oxidoreductase RuleBase RU003427 EMBL ABK87393.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	malate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	L-malate dehydrogenase activity Inferred from electronic annotation. Source: EC NAD binding Inferred from electronic annotation. Source: InterPro malate dehydrogenase (oxaloacetate-decarboxylating) activity Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	59	1	Proton donor By similarity PIRSR PIRSR000106-1
	Active site	114	1	Proton acceptor By similarity PIRSR PIRSR000106-1
	Metal binding	156	1	Divalent metal cation By similarity PIRSR PIRSR000106-3
	Metal binding	157	1	Divalent metal cation By similarity PIRSR PIRSR000106-3
	Metal binding	182	1	Divalent metal cation By similarity PIRSR PIRSR000106-3

Sequences

	Sequence		Length	Mass (Da)
	A0RJK0 [UniParc]. Last modified January 9, 2007. Version 1. Checksum: ADD10F9721690612	FASTA	434	46,606
	10 20 30 40 50 60 MFVVRPLGEI DISKNNLRRV DSLSTLREEA LHMHKVHQGK LETVSKVKVE NAKDLSLAYS 70 80 90 100 110 120 PGVAEPCKEI YDDKSKVYEY TMKGNMVAVV TDGTAVLGLG NIGPEASLPV MEGKAVLFKS 130 140 150 160 170 180 FAGVDAFPIA LNTNDVDKIV ETVKLMEPTF GGVNLEDIAA PNCFIIEERL KKETNIPIFH 190 200 210 220 230 240 DDQHGTAIVT VAGLVNALKL VGKKMSDIKV VANGAGAAGI AIIKLLYRYG VRDIIMCDRK 250 260 270 280 290 300 GAIYEGRPTG MNPVKDEVAK YTNKNRIEGS LADVVQGADV FIGVSAEGAL TEEMVRTMND 310 320 330 340 350 360 NAIIFAMANP VPEIMPELAK AAGAAVVGTG RSDFANQVNN VLAFPGIFRG ALDVHATQIN 370 380 390 400 410 420 EEMKMAAVQA IAELVAEDEL NADYIIPAPF DARVAPQVAA YVAKAAMETG VARRQVDPNE 430 VAEKTKQLAL IGKE

References

[1]

"The complete genome sequence of Bacillus thuringiensis Al Hakam." Challacombe J.F., Altherr M.R., Xie G., Bhotika S.S., Brown N., Bruce D., Campbell C.S., Campbell M.L., Chen J., Chertkov O., Cleland C., Dimitrijevic M., Doggett N.A., Fawcett J.J., Glavina T., Goodwin L.A., Green L.D., Han C.S. , Hill K.K., Hitchcock P., Jackson P.J., Keim P., Kewalramani A.R., Longmire J., Lucas S., Malfatti S., Martinez D., McMurry K., Meincke L.J., Misra M., Moseman B.L., Mundt M., Munk A.C., Okinaka R.T., Parson-Quintana B., Reilly L.P., Richardson P., Robinson D.L., Saunders E., Tapia R., Tesmer J.G., Thayer N., Thompson L.S., Tice H., Ticknor L.O., Wills P.L., Gilna P., Brettin T.S. J. Bacteriol. 189:3680-3681(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Al Hakam EMBL ABK87393.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000485 Genomic DNA. Translation: ABK87393.1.
RefSeq	YP_896900.1. NC_008600.1.
3D structure databases
ProteinModelPortal	A0RJK0.
SMR	A0RJK0. Positions 24-407.
ModBase	Search...
Protein-protein interaction databases
STRING	412694.BALH_4186.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABK87393; ABK87393; BALH_4186.
GeneID	4544288.
KEGG	btl:BALH_4186.
PATRIC	19001282. VBIBacThu63319_4637.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0281.
HOGENOM	HOG000132447.
KO	K00027.
OMA	TIINEEM.
ProtClustDB	CLSK2485177.
Enzyme and pathway databases
BioCyc	BTHU412694:GH1W-3974-MONOMER.
Family and domain databases
Gene3D	3.40.50.10380. 1 hit. 3.40.50.720. 1 hit.
InterPro	IPR015884. Malic_enzyme_CS. IPR012301. Malic_N. IPR012302. Malic_NAD-bd. IPR001891. Malic_OxRdtase. IPR016040. NAD(P)-bd_dom. [Graphical view]
Pfam	PF00390. malic. 1 hit. PF03949. Malic_M. 1 hit. [Graphical view]
PIRSF	PIRSF000106. ME. 1 hit.
PRINTS	PR00072. MALOXRDTASE.
SMART	SM00919. Malic_M. 1 hit. [Graphical view]
PROSITE	PS00331. MALIC_ENZYMES. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A0RJK0_BACAH

Accession

Primary (citable) accession number: A0RJK0

Entry history

Integrated into UniProtKB/TrEMBL:	January 9, 2007
Last sequence update:	January 9, 2007
Last modified:	May 1, 2013
This is version 53 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)