Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

A0RJK0

- A0RJK0_BACAH

UniProt

A0RJK0 - A0RJK0_BACAH

Protein
Submitted name:

Malate dehydrogenase

Gene

mdh

Organism
Bacillus thuringiensis (strain Al Hakam)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 62 (01 Oct 2014)
      Sequence version 1 (09 Jan 2007)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Cofactori

    Divalent metal cations. Prefers magnesium or manganese.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei59 – 591Proton donorUniRule annotation
    Active sitei114 – 1141Proton acceptorUniRule annotation
    Metal bindingi156 – 1561Divalent metal cationUniRule annotation
    Metal bindingi157 – 1571Divalent metal cationUniRule annotation
    Metal bindingi182 – 1821Divalent metal cationUniRule annotation

    GO - Molecular functioni

    1. L-malate dehydrogenase activity Source: UniProtKB-EC
    2. malate dehydrogenase (decarboxylating) (NAD+) activity Source: InterPro
    3. metal ion binding Source: UniProtKB-KW
    4. NAD binding Source: InterPro

    GO - Biological processi

    1. malate metabolic process Source: InterPro

    Keywords - Molecular functioni

    OxidoreductaseUniRule annotationImported

    Keywords - Ligandi

    Metal-bindingUniRule annotation

    Enzyme and pathway databases

    BioCyciBTHU412694:GH1W-4088-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Malate dehydrogenaseImported (EC:1.1.1.37Imported)
    Gene namesi
    Name:mdhImported
    Ordered Locus Names:BALH_4186Imported
    OrganismiBacillus thuringiensis (strain Al Hakam)Imported
    Taxonomic identifieri412694 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group
    ProteomesiUP000000761: Chromosome

    Interactioni

    Protein-protein interaction databases

    STRINGi412694.BALH_4186.

    Structurei

    3D structure databases

    ProteinModelPortaliA0RJK0.
    SMRiA0RJK0. Positions 24-407.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the malic enzymes family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0281.
    HOGENOMiHOG000132447.
    KOiK00027.
    OMAiKIEVTPK.
    OrthoDBiEOG6QCD9W.

    Family and domain databases

    Gene3Di3.40.50.10380. 1 hit.
    3.40.50.720. 1 hit.
    InterProiIPR015884. Malic_enzyme_CS.
    IPR012301. Malic_N_dom.
    IPR012302. Malic_NAD-bd.
    IPR001891. Malic_OxRdtase.
    IPR016040. NAD(P)-bd_dom.
    [Graphical view]
    PfamiPF00390. malic. 1 hit.
    PF03949. Malic_M. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000106. ME. 1 hit.
    PRINTSiPR00072. MALOXRDTASE.
    SMARTiSM00919. Malic_M. 1 hit.
    [Graphical view]
    PROSITEiPS00331. MALIC_ENZYMES. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A0RJK0-1 [UniParc]FASTAAdd to Basket

    « Hide

    MFVVRPLGEI DISKNNLRRV DSLSTLREEA LHMHKVHQGK LETVSKVKVE    50
    NAKDLSLAYS PGVAEPCKEI YDDKSKVYEY TMKGNMVAVV TDGTAVLGLG 100
    NIGPEASLPV MEGKAVLFKS FAGVDAFPIA LNTNDVDKIV ETVKLMEPTF 150
    GGVNLEDIAA PNCFIIEERL KKETNIPIFH DDQHGTAIVT VAGLVNALKL 200
    VGKKMSDIKV VANGAGAAGI AIIKLLYRYG VRDIIMCDRK GAIYEGRPTG 250
    MNPVKDEVAK YTNKNRIEGS LADVVQGADV FIGVSAEGAL TEEMVRTMND 300
    NAIIFAMANP VPEIMPELAK AAGAAVVGTG RSDFANQVNN VLAFPGIFRG 350
    ALDVHATQIN EEMKMAAVQA IAELVAEDEL NADYIIPAPF DARVAPQVAA 400
    YVAKAAMETG VARRQVDPNE VAEKTKQLAL IGKE 434
    Length:434
    Mass (Da):46,606
    Last modified:January 9, 2007 - v1
    Checksum:iADD10F9721690612
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000485 Genomic DNA. Translation: ABK87393.1.
    RefSeqiYP_896900.1. NC_008600.1.

    Genome annotation databases

    EnsemblBacteriaiABK87393; ABK87393; BALH_4186.
    GeneIDi4544288.
    KEGGibtl:BALH_4186.
    PATRICi19001282. VBIBacThu63319_4637.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000485 Genomic DNA. Translation: ABK87393.1 .
    RefSeqi YP_896900.1. NC_008600.1.

    3D structure databases

    ProteinModelPortali A0RJK0.
    SMRi A0RJK0. Positions 24-407.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 412694.BALH_4186.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABK87393 ; ABK87393 ; BALH_4186 .
    GeneIDi 4544288.
    KEGGi btl:BALH_4186.
    PATRICi 19001282. VBIBacThu63319_4637.

    Phylogenomic databases

    eggNOGi COG0281.
    HOGENOMi HOG000132447.
    KOi K00027.
    OMAi KIEVTPK.
    OrthoDBi EOG6QCD9W.

    Enzyme and pathway databases

    BioCyci BTHU412694:GH1W-4088-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.10380. 1 hit.
    3.40.50.720. 1 hit.
    InterProi IPR015884. Malic_enzyme_CS.
    IPR012301. Malic_N_dom.
    IPR012302. Malic_NAD-bd.
    IPR001891. Malic_OxRdtase.
    IPR016040. NAD(P)-bd_dom.
    [Graphical view ]
    Pfami PF00390. malic. 1 hit.
    PF03949. Malic_M. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000106. ME. 1 hit.
    PRINTSi PR00072. MALOXRDTASE.
    SMARTi SM00919. Malic_M. 1 hit.
    [Graphical view ]
    PROSITEi PS00331. MALIC_ENZYMES. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Al HakamImported.

    Entry informationi

    Entry nameiA0RJK0_BACAH
    AccessioniPrimary (citable) accession number: A0RJK0
    Entry historyi
    Integrated into UniProtKB/TrEMBL: January 9, 2007
    Last sequence update: January 9, 2007
    Last modified: October 1, 2014
    This is version 62 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3