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A0RHN9

- FMT_BACAH

UniProt

A0RHN9 - FMT_BACAH

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Protein
Methionyl-tRNA formyltransferase
Gene
fmt, BALH_3497
Organism
Bacillus thuringiensis (strain Al Hakam)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by: (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP By similarity.UniRule annotation

Catalytic activityi

10-formyltetrahydrofolate + L-methionyl-tRNA(fMet) = tetrahydrofolate + N-formylmethionyl-tRNA(fMet).UniRule annotation

GO - Molecular functioni

  1. methionyl-tRNA formyltransferase activity Source: UniProtKB-HAMAP
  2. methyltransferase activity Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Transferase

Keywords - Biological processi

Protein biosynthesis

Enzyme and pathway databases

BioCyciBTHU412694:GH1W-3425-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Methionyl-tRNA formyltransferase (EC:2.1.2.9)
Gene namesi
Name:fmt
Ordered Locus Names:BALH_3497
OrganismiBacillus thuringiensis (strain Al Hakam)
Taxonomic identifieri412694 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group
ProteomesiUP000000761: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 314314Methionyl-tRNA formyltransferaseUniRule annotation
PRO_1000020018Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi412694.BALH_3497.

Structurei

3D structure databases

ProteinModelPortaliA0RHN9.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni110 – 1134Tetrahydrofolate (THF) binding By similarity

Sequence similaritiesi

Belongs to the Fmt family.

Phylogenomic databases

eggNOGiCOG0223.
HOGENOMiHOG000261177.
KOiK00604.
OMAiQRFKIYE.
OrthoDBiEOG6B09WV.

Family and domain databases

Gene3Di3.10.25.10. 1 hit.
3.40.50.170. 1 hit.
HAMAPiMF_00182. Formyl_trans.
InterProiIPR005794. Fmt.
IPR005793. Formyl_trans_C.
IPR002376. Formyl_transf_N.
IPR011034. Formyl_transferase_C-like.
IPR001555. GART_AS.
IPR015518. Met_tRNA_Form_TA-like.
[Graphical view]
PANTHERiPTHR11138. PTHR11138. 1 hit.
PfamiPF02911. Formyl_trans_C. 1 hit.
PF00551. Formyl_trans_N. 1 hit.
[Graphical view]
SUPFAMiSSF50486. SSF50486. 1 hit.
SSF53328. SSF53328. 1 hit.
TIGRFAMsiTIGR00460. fmt. 1 hit.
PROSITEiPS00373. GART. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A0RHN9-1 [UniParc]FASTAAdd to Basket

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MIKVVFMGTP DFSVPVLRRL IEDGYDVIGV VTQPDRPVGR KKVLTPTPVK    50
VEAEKHGIPV LQPLRIREKD EYEKVLALEP DLIVTAAFGQ IVPNEILEAP 100
KYGCINVHAS LLPELRGGAP IHYAIMEGKE KTGITIMYMV EKLDAGDILT 150
QVEVEIEERE TTGSLFDKLS EAGAHLLSKT VPLLIQGKLE PIKQNEEEVT 200
FAYNIKREQE KIDWTKTGEE VYNHIRGLNP WPVAYTTLAG QVVKVWWGEK 250
VPVTKSAEAG TIVAIEEDGF VVATGNETGV KITELQPSGK KRMSCSQFLR 300
GTKPEIGTKL GENA 314
Length:314
Mass (Da):34,736
Last modified:January 9, 2007 - v1
Checksum:i8E81D02492DABEE2
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000485 Genomic DNA. Translation: ABK86732.1.
RefSeqiYP_896239.1. NC_008600.1.

Genome annotation databases

EnsemblBacteriaiABK86732; ABK86732; BALH_3497.
GeneIDi4542709.
KEGGibtl:BALH_3497.
PATRICi18999745. VBIBacThu63319_3872.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000485 Genomic DNA. Translation: ABK86732.1 .
RefSeqi YP_896239.1. NC_008600.1.

3D structure databases

ProteinModelPortali A0RHN9.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 412694.BALH_3497.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABK86732 ; ABK86732 ; BALH_3497 .
GeneIDi 4542709.
KEGGi btl:BALH_3497.
PATRICi 18999745. VBIBacThu63319_3872.

Phylogenomic databases

eggNOGi COG0223.
HOGENOMi HOG000261177.
KOi K00604.
OMAi QRFKIYE.
OrthoDBi EOG6B09WV.

Enzyme and pathway databases

BioCyci BTHU412694:GH1W-3425-MONOMER.

Family and domain databases

Gene3Di 3.10.25.10. 1 hit.
3.40.50.170. 1 hit.
HAMAPi MF_00182. Formyl_trans.
InterProi IPR005794. Fmt.
IPR005793. Formyl_trans_C.
IPR002376. Formyl_transf_N.
IPR011034. Formyl_transferase_C-like.
IPR001555. GART_AS.
IPR015518. Met_tRNA_Form_TA-like.
[Graphical view ]
PANTHERi PTHR11138. PTHR11138. 1 hit.
Pfami PF02911. Formyl_trans_C. 1 hit.
PF00551. Formyl_trans_N. 1 hit.
[Graphical view ]
SUPFAMi SSF50486. SSF50486. 1 hit.
SSF53328. SSF53328. 1 hit.
TIGRFAMsi TIGR00460. fmt. 1 hit.
PROSITEi PS00373. GART. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Al Hakam.

Entry informationi

Entry nameiFMT_BACAH
AccessioniPrimary (citable) accession number: A0RHN9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: January 9, 2007
Last modified: May 14, 2014
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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