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A0RET0 (UPPP4_BACAH) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 54. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Undecaprenyl-diphosphatase 4

EC=3.6.1.27
Alternative name(s):
Bacitracin resistance protein 4
Undecaprenyl pyrophosphate phosphatase 4
Gene names
Name:uppP4
Ordered Locus Names:BALH_2434
OrganismBacillus thuringiensis (strain Al Hakam) [Complete proteome] [HAMAP]
Taxonomic identifier412694 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group

Protein attributes

Sequence length259 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin By similarity. HAMAP-Rule MF_01006

Catalytic activity

Ditrans,octacis-undecaprenyl diphosphate + H2O = ditrans,octacis-undecaprenyl phosphate + phosphate. HAMAP-Rule MF_01006

Subcellular location

Cell membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01006.

Miscellaneous

Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.

Sequence similarities

Belongs to the UppP family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 259259Undecaprenyl-diphosphatase 4 HAMAP-Rule MF_01006
PRO_0000290687

Regions

Transmembrane1 – 2121Helical; Potential
Transmembrane39 – 5921Helical; Potential
Transmembrane71 – 9121Helical; Potential
Transmembrane99 – 11921Helical; Potential
Transmembrane133 – 15321Helical; Potential
Transmembrane173 – 19321Helical; Potential
Transmembrane208 – 22821Helical; Potential
Transmembrane239 – 25921Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
A0RET0 [UniParc].

Last modified January 9, 2007. Version 1.
Checksum: 7E4301B612EB6332

FASTA25929,214
        10         20         30         40         50         60 
MNWLEAFILG IIQGLTEFLP ISSTGHLYLG RHLFQLDEAG LFLDTMLHIG TLLAVFIYYK 

        70         80         90        100        110        120 
KEFIYLIKNP FSKLMLLLIV GTIPAVVIGL LFKDFFEDIS KTGITIGWEF LVTGFFLYMA 

       130        140        150        160        170        180 
DKQKNGRKKM DDITYKDAFI IGSFQAAAIF PAISRSGMTI VAALWRKLDR ETAAYFSFLL 

       190        200        210        220        230        240 
STPAIVGAII LQFADVFQGK AESISNTSLI VGTLSAAFFG YIAVSWMIQY LKRHSLKVFA 

       250 
YYVWGLGIII ITLQYTHVF 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000485 Genomic DNA. Translation: ABK85723.1.
RefSeqYP_895230.1. NC_008600.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING412694.BALH_2434.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABK85723; ABK85723; BALH_2434.
GeneID4542985.
KEGGbtl:BALH_2434.
PATRIC18997451. VBIBacThu63319_2725.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1968.
HOGENOMHOG000218357.
KOK06153.
OMAWEFLATG.
OrthoDBEOG6QP13M.
ProtClustDBPRK00281.

Enzyme and pathway databases

BioCycBTHU412694:GH1W-2415-MONOMER.

Family and domain databases

HAMAPMF_01006. Undec_diphosphatase.
InterProIPR003824. UppP.
[Graphical view]
PfamPF02673. BacA. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameUPPP4_BACAH
AccessionPrimary (citable) accession number: A0RET0
Entry history
Integrated into UniProtKB/Swiss-Prot: June 12, 2007
Last sequence update: January 9, 2007
Last modified: February 19, 2014
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families