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A0RD76

- A0RD76_BACAH

UniProt

A0RD76 - A0RD76_BACAH

Protein

Alanine racemase

Gene

BALH_1850

Organism
Bacillus thuringiensis (strain Al Hakam)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 64 (01 Oct 2014)
      Sequence version 1 (09 Jan 2007)
      Previous versions | rss
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    Functioni

    Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

    Catalytic activityi

    L-alanine = D-alanine.UniRule annotationSAAS annotation

    Cofactori

    Pyridoxal phosphate.UniRule annotationSAAS annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei58 – 581Proton acceptor; specific for D-alanineUniRule annotation
    Binding sitei156 – 1561SubstrateUniRule annotation
    Active sitei286 – 2861Proton acceptor; specific for L-alanineUniRule annotation
    Binding sitei334 – 3341Substrate; via amide nitrogenUniRule annotation

    GO - Molecular functioni

    1. alanine racemase activity Source: UniProtKB-HAMAP
    2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. D-alanine biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    IsomeraseUniRule annotationSAAS annotationImported

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciBTHU412694:GH1W-1861-MONOMER.
    UniPathwayiUPA00042; UER00497.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
    Gene namesi
    Ordered Locus Names:BALH_1850Imported
    OrganismiBacillus thuringiensis (strain Al Hakam)Imported
    Taxonomic identifieri412694 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group
    ProteomesiUP000000761: Chromosome

    PTM / Processingi

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei58 – 581N6-(pyridoxal phosphate)lysineUniRule annotation

    Interactioni

    Protein-protein interaction databases

    STRINGi412694.BALH_1850.

    Structurei

    3D structure databases

    ProteinModelPortaliA0RD76.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the alanine racemase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0787.
    HOGENOMiHOG000031444.
    KOiK01775.
    OMAiLWQLEAI.
    OrthoDBiEOG6PP9NJ.

    Family and domain databases

    Gene3Di2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPiMF_01201. Ala_racemase.
    InterProiIPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR020622. Ala_racemase_pyridoxalP-BS.
    IPR029066. PLP-binding_barrel.
    [Graphical view]
    PfamiPF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view]
    PRINTSiPR00992. ALARACEMASE.
    SMARTiSM01005. Ala_racemase_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsiTIGR00492. alr. 1 hit.
    PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A0RD76-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKREIEWNAI IELGVRPMSL KYGRDTIVEV DLNAVKHNVK EFKKRVNDEN    50
    IAMMAAVKAN GYGHGAVEVA KAAIEAGINQ LAIAFVDEAI ELREAGINVP 100
    ILILGYTSVA AAEEAIQYDV MMTVYRSEDL QGINEIANRL QKKAQIQVKI 150
    DTGMSRIGLQ EEEVKPFLEE LKRMEYVEVV GMFTHYSTAD EIDKSYTNMQ 200
    TSLFEKAVNT AKELGIHIPY IHSSNSAGSM ELSNTFQNMV RVGIGIYGMY 250
    PSKEVNHSVV SLQPALSLKS KVAHIKHAKK NRGVSYGNTY VTTGEEWIAT 300
    VPIGYADGYN RQLSNKGHAL INGVRVPVIG RVCMDQLMLD VSKAMPVQVG 350
    DEVVFYGKQG EENIAVEEIA DMLGTINYEV TCMLDRRIPR VYKENNETTA 400
    VVNILRKN 408
    Length:408
    Mass (Da):45,424
    Last modified:January 9, 2007 - v1
    Checksum:iBAB1D8690DE21522
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000485 Genomic DNA. Translation: ABK85169.1.
    RefSeqiYP_894676.1. NC_008600.1.

    Genome annotation databases

    EnsemblBacteriaiABK85169; ABK85169; BALH_1850.
    GeneIDi4545500.
    KEGGibtl:BALH_1850.
    PATRICi18996154. VBIBacThu63319_2079.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000485 Genomic DNA. Translation: ABK85169.1 .
    RefSeqi YP_894676.1. NC_008600.1.

    3D structure databases

    ProteinModelPortali A0RD76.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 412694.BALH_1850.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABK85169 ; ABK85169 ; BALH_1850 .
    GeneIDi 4545500.
    KEGGi btl:BALH_1850.
    PATRICi 18996154. VBIBacThu63319_2079.

    Phylogenomic databases

    eggNOGi COG0787.
    HOGENOMi HOG000031444.
    KOi K01775.
    OMAi LWQLEAI.
    OrthoDBi EOG6PP9NJ.

    Enzyme and pathway databases

    UniPathwayi UPA00042 ; UER00497 .
    BioCyci BTHU412694:GH1W-1861-MONOMER.

    Family and domain databases

    Gene3Di 2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPi MF_01201. Ala_racemase.
    InterProi IPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR020622. Ala_racemase_pyridoxalP-BS.
    IPR029066. PLP-binding_barrel.
    [Graphical view ]
    Pfami PF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view ]
    PRINTSi PR00992. ALARACEMASE.
    SMARTi SM01005. Ala_racemase_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsi TIGR00492. alr. 1 hit.
    PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Al HakamImported.

    Entry informationi

    Entry nameiA0RD76_BACAH
    AccessioniPrimary (citable) accession number: A0RD76
    Entry historyi
    Integrated into UniProtKB/TrEMBL: January 9, 2007
    Last sequence update: January 9, 2007
    Last modified: October 1, 2014
    This is version 64 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3