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A0RD76

- A0RD76_BACAH

UniProt

A0RD76 - A0RD76_BACAH

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Protein

Alanine racemase

Gene

BALH_1850

Organism
Bacillus thuringiensis (strain Al Hakam)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotationSAAS annotation

Cofactori

Pyridoxal phosphate.UniRule annotationSAAS annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei58 – 581Proton acceptor; specific for D-alanineUniRule annotation
Binding sitei156 – 1561SubstrateUniRule annotation
Active sitei286 – 2861Proton acceptor; specific for L-alanineUniRule annotation
Binding sitei334 – 3341Substrate; via amide nitrogenUniRule annotation

GO - Molecular functioni

  1. alanine racemase activity Source: UniProtKB-HAMAP
  2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-alanine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotation

Keywords - Ligandi

Pyridoxal phosphateUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciBTHU412694:GH1W-1861-MONOMER.
UniPathwayiUPA00042; UER00497.

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
Ordered Locus Names:BALH_1850Imported
OrganismiBacillus thuringiensis (strain Al Hakam)Imported
Taxonomic identifieri412694 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group
ProteomesiUP000000761: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei58 – 581N6-(pyridoxal phosphate)lysineUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi412694.BALH_1850.

Structurei

3D structure databases

ProteinModelPortaliA0RD76.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the alanine racemase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0787.
HOGENOMiHOG000031444.
KOiK01775.
OMAiLWQLEAI.
OrthoDBiEOG6PP9NJ.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.
PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A0RD76-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKREIEWNAI IELGVRPMSL KYGRDTIVEV DLNAVKHNVK EFKKRVNDEN
60 70 80 90 100
IAMMAAVKAN GYGHGAVEVA KAAIEAGINQ LAIAFVDEAI ELREAGINVP
110 120 130 140 150
ILILGYTSVA AAEEAIQYDV MMTVYRSEDL QGINEIANRL QKKAQIQVKI
160 170 180 190 200
DTGMSRIGLQ EEEVKPFLEE LKRMEYVEVV GMFTHYSTAD EIDKSYTNMQ
210 220 230 240 250
TSLFEKAVNT AKELGIHIPY IHSSNSAGSM ELSNTFQNMV RVGIGIYGMY
260 270 280 290 300
PSKEVNHSVV SLQPALSLKS KVAHIKHAKK NRGVSYGNTY VTTGEEWIAT
310 320 330 340 350
VPIGYADGYN RQLSNKGHAL INGVRVPVIG RVCMDQLMLD VSKAMPVQVG
360 370 380 390 400
DEVVFYGKQG EENIAVEEIA DMLGTINYEV TCMLDRRIPR VYKENNETTA

VVNILRKN
Length:408
Mass (Da):45,424
Last modified:January 9, 2007 - v1
Checksum:iBAB1D8690DE21522
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000485 Genomic DNA. Translation: ABK85169.1.
RefSeqiYP_894676.1. NC_008600.1.

Genome annotation databases

EnsemblBacteriaiABK85169; ABK85169; BALH_1850.
GeneIDi4545500.
KEGGibtl:BALH_1850.
PATRICi18996154. VBIBacThu63319_2079.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000485 Genomic DNA. Translation: ABK85169.1 .
RefSeqi YP_894676.1. NC_008600.1.

3D structure databases

ProteinModelPortali A0RD76.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 412694.BALH_1850.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABK85169 ; ABK85169 ; BALH_1850 .
GeneIDi 4545500.
KEGGi btl:BALH_1850.
PATRICi 18996154. VBIBacThu63319_2079.

Phylogenomic databases

eggNOGi COG0787.
HOGENOMi HOG000031444.
KOi K01775.
OMAi LWQLEAI.
OrthoDBi EOG6PP9NJ.

Enzyme and pathway databases

UniPathwayi UPA00042 ; UER00497 .
BioCyci BTHU412694:GH1W-1861-MONOMER.

Family and domain databases

Gene3Di 2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPi MF_01201. Ala_racemase.
InterProi IPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view ]
Pfami PF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view ]
PRINTSi PR00992. ALARACEMASE.
SMARTi SM01005. Ala_racemase_C. 1 hit.
[Graphical view ]
SUPFAMi SSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsi TIGR00492. alr. 1 hit.
PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Al HakamImported.

Entry informationi

Entry nameiA0RD76_BACAH
AccessioniPrimary (citable) accession number: A0RD76
Entry historyi
Integrated into UniProtKB/TrEMBL: January 9, 2007
Last sequence update: January 9, 2007
Last modified: October 29, 2014
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3